BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

239 related articles for article (PubMed ID: 17258766)

  • 1. Maturation of shark single-domain (IgNAR) antibodies: evidence for induced-fit binding.
    Stanfield RL; Dooley H; Verdino P; Flajnik MF; Wilson IA
    J Mol Biol; 2007 Mar; 367(2):358-72. PubMed ID: 17258766
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structure of a shark single-domain antibody V region in complex with lysozyme.
    Stanfield RL; Dooley H; Flajnik MF; Wilson IA
    Science; 2004 Sep; 305(5691):1770-3. PubMed ID: 15319492
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rapid isolation of IgNAR variable single-domain antibody fragments from a shark synthetic library.
    Shao CY; Secombes CJ; Porter AJ
    Mol Immunol; 2007 Jan; 44(4):656-65. PubMed ID: 16500706
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dissection of the IgNAR V domain: molecular scanning and orthologue database mining define novel IgNAR hallmarks and affinity maturation mechanisms.
    Fennell BJ; Darmanin-Sheehan A; Hufton SE; Calabro V; Wu L; Müller MR; Cao W; Gill D; Cunningham O; Finlay WJ
    J Mol Biol; 2010 Jul; 400(2):155-70. PubMed ID: 20450918
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure of a shark IgNAR antibody variable domain and modeling of an early-developmental isotype.
    Streltsov VA; Carmichael JA; Nuttall SD
    Protein Sci; 2005 Nov; 14(11):2901-9. PubMed ID: 16199666
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Diversity and repertoire of IgW and IgM VH families in the newborn nurse shark.
    Rumfelt LL; Lohr RL; Dooley H; Flajnik MF
    BMC Immunol; 2004 May; 5():8. PubMed ID: 15132758
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Selection and characterization of naturally occurring single-domain (IgNAR) antibody fragments from immunized sharks by phage display.
    Dooley H; Flajnik MF; Porter AJ
    Mol Immunol; 2003 Sep; 40(1):25-33. PubMed ID: 12909128
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural insights and biomedical potential of IgNAR scaffolds from sharks.
    Zielonka S; Empting M; Grzeschik J; Könning D; Barelle CJ; Kolmar H
    MAbs; 2015; 7(1):15-25. PubMed ID: 25523873
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Isolation and characterization of an IgNAR variable domain specific for the human mitochondrial translocase receptor Tom70.
    Nuttall SD; Krishnan UV; Doughty L; Pearson K; Ryan MT; Hoogenraad NJ; Hattarki M; Carmichael JA; Irving RA; Hudson PJ
    Eur J Biochem; 2003 Sep; 270(17):3543-54. PubMed ID: 12919318
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dimerisation strategies for shark IgNAR single domain antibody fragments.
    Simmons DP; Abregu FA; Krishnan UV; Proll DF; Streltsov VA; Doughty L; Hattarki MK; Nuttall SD
    J Immunol Methods; 2006 Aug; 315(1-2):171-84. PubMed ID: 16962608
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selection and affinity maturation of IgNAR variable domains targeting Plasmodium falciparum AMA1.
    Nuttall SD; Humberstone KS; Krishnan UV; Carmichael JA; Doughty L; Hattarki M; Coley AM; Casey JL; Anders RF; Foley M; Irving RA; Hudson PJ
    Proteins; 2004 Apr; 55(1):187-97. PubMed ID: 14997552
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vitro improvement of a shark IgNAR antibody by Qbeta replicase mutation and ribosome display mimics in vivo affinity maturation.
    Kopsidas G; Roberts AS; Coia G; Streltsov VA; Nuttall SD
    Immunol Lett; 2006 Nov; 107(2):163-8. PubMed ID: 17069896
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transcriptomic analysis of immunoglobulin novel antigen receptor (IgNAR) heavy chain constant domains of brownbanded bamboo shark (Chiloscyllium punctatum).
    De Silva DPN; Tan E; Mizuno N; Hosoya S; Reza MS; Watabe S; Kinoshita S; Asakawa S
    Fish Shellfish Immunol; 2019 Jan; 84():370-376. PubMed ID: 30291985
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The generation and selection of single-domain, v region libraries from nurse sharks.
    Flajnik MF; Dooley H
    Methods Mol Biol; 2009; 562():71-82. PubMed ID: 19554288
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Augmented Binary Substitution: Single-pass CDR germ-lining and stabilization of therapeutic antibodies.
    Townsend S; Fennell BJ; Apgar JR; Lambert M; McDonnell B; Grant J; Wade J; Franklin E; Foy N; Ní Shúilleabháin D; Fields C; Darmanin-Sheehan A; King A; Paulsen JE; Hickling TP; Tchistiakova L; Cunningham O; Finlay WJ
    Proc Natl Acad Sci U S A; 2015 Dec; 112(50):15354-9. PubMed ID: 26621728
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Monoclonal antibodies for the identification and purification of vNAR domains and IgNAR immunoglobulins from the horn shark Heterodontus francisci.
    Juarez K; Dubberke G; Lugo P; Koch-Nolte F; Buck F; Haag F; Licea A
    Hybridoma (Larchmt); 2011 Aug; 30(4):323-9. PubMed ID: 21851231
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural analysis, selection, and ontogeny of the shark new antigen receptor (IgNAR): identification of a new locus preferentially expressed in early development.
    Diaz M; Stanfield RL; Greenberg AS; Flajnik MF
    Immunogenetics; 2002 Oct; 54(7):501-12. PubMed ID: 12389098
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structure of anti-Hen egg white lysozyme antibody (HyHEL-10) Fv-antigen complex. Local structural changes in the protein antigen and water-mediated interactions of Fv-antigen and light chain-heavy chain interfaces.
    Kondo H; Shiroishi M; Matsushima M; Tsumoto K; Kumagai I
    J Biol Chem; 1999 Sep; 274(39):27623-31. PubMed ID: 10488102
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Recombinant shark natural antibodies to thyroglobulin.
    Schluter SF; Jensen I; Ramsland PA; Marchalonis JJ
    J Mol Recognit; 2005; 18(5):404-12. PubMed ID: 15954089
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins.
    Feige MJ; Gräwert MA; Marcinowski M; Hennig J; Behnke J; Ausländer D; Herold EM; Peschek J; Castro CD; Flajnik M; Hendershot LM; Sattler M; Groll M; Buchner J
    Proc Natl Acad Sci U S A; 2014 Jun; 111(22):8155-60. PubMed ID: 24830426
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.