385 related articles for article (PubMed ID: 17258905)
1. Design, synthesis, and biological evaluation of substituted 2-alkylthio-1,5-diarylimidazoles as selective COX-2 inhibitors.
Navidpour L; Shadnia H; Shafaroodi H; Amini M; Dehpour AR; Shafiee A
Bioorg Med Chem; 2007 Mar; 15(5):1976-82. PubMed ID: 17258905
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis, and biological evaluation of substituted 3-alkylthio-4,5-diaryl-4H-1,2,4-triazoles as selective COX-2 inhibitors.
Navidpour L; Shafaroodi H; Abdi K; Amini M; Ghahremani MH; Dehpour AR; Shafiee A
Bioorg Med Chem; 2006 Apr; 14(8):2507-17. PubMed ID: 16337127
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis, and biological evaluation of 6-substituted-3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: a novel class of diarylheterocyclic selective cyclooxygenase-2 inhibitors.
Praveen Rao PN; Amini M; Li H; Habeeb AG; Knaus EE
J Med Chem; 2003 Nov; 46(23):4872-82. PubMed ID: 14584938
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and structure-activity relationship of a new series of COX-2 selective inhibitors: 1,5-diarylimidazoles.
Almansa C; Alfón J; de Arriba AF; Cavalcanti FL; Escamilla I; Gómez LA; Miralles A; Soliva R; Bartrolí J; Carceller E; Merlos M; García-Rafanell J
J Med Chem; 2003 Jul; 46(16):3463-75. PubMed ID: 12877584
[TBL] [Abstract][Full Text] [Related]
5. Synthesis, anti-inflammatory activity and COX-1/COX-2 inhibition of novel substituted cyclic imides. Part 1: Molecular docking study.
Abdel-Aziz AA; ElTahir KE; Asiri YA
Eur J Med Chem; 2011 May; 46(5):1648-55. PubMed ID: 21388719
[TBL] [Abstract][Full Text] [Related]
6. 1,2-Diarylimidazoles as potent, cyclooxygenase-2 selective, and orally active antiinflammatory agents.
Khanna IK; Weier RM; Yu Y; Xu XD; Koszyk FJ; Collins PW; Koboldt CM; Veenhuizen AW; Perkins WE; Casler JJ; Masferrer JL; Zhang YY; Gregory SA; Seibert K; Isakson PC
J Med Chem; 1997 May; 40(11):1634-47. PubMed ID: 9171873
[TBL] [Abstract][Full Text] [Related]
7. Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 2. 1,3,4- and 1,2,4-thiadiazole series.
Song Y; Connor DT; Sercel AD; Sorenson RJ; Doubleday R; Unangst PC; Roth BD; Beylin VG; Gilbertsen RB; Chan K; Schrier DJ; Guglietta A; Bornemeier DA; Dyer RD
J Med Chem; 1999 Apr; 42(7):1161-9. PubMed ID: 10197960
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis, and biological evaluation of 1,3-diarylprop-2-en-1-ones : a novel class of cyclooxygenase-2 inhibitors.
Zarghi A; Arfaee S; Rao PN; Knaus EE
Bioorg Med Chem; 2006 Apr; 14(8):2600-5. PubMed ID: 16356730
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis, and biological evaluation of N-acetyl-2-(or 3-)carboxymethylbenzenesulfonamides as cyclooxygenase isozyme inhibitors.
Chen QH; Rao PN; Knaus EE
Bioorg Med Chem; 2005 Aug; 13(15):4694-703. PubMed ID: 15914011
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis, and biological evaluation of linear 1-(4-, 3- or 2-methylsulfonylphenyl)-2-phenylacetylenes: a novel class of cyclooxygenase-2 inhibitors.
Chen QH; Rao PN; Knaus EE
Bioorg Med Chem; 2005 Dec; 13(23):6425-34. PubMed ID: 16099663
[TBL] [Abstract][Full Text] [Related]
11. Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 1. Thiazolone and oxazolone series.
Song Y; Connor DT; Doubleday R; Sorenson RJ; Sercel AD; Unangst PC; Roth BD; Gilbertsen RB; Chan K; Schrier DJ; Guglietta A; Bornemeier DA; Dyer RD
J Med Chem; 1999 Apr; 42(7):1151-60. PubMed ID: 10197959
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis, and anti-inflammatory evaluation of a series of novel amino acid-binding 1,5-diarylpyrazole derivatives.
Li MH; Yin LL; Cai MJ; Zhang WY; Huang Y; Wang X; Zhu XZ; Shen JK
Acta Pharmacol Sin; 2005 Jul; 26(7):865-72. PubMed ID: 15960895
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
Rao PN; Chen QH; Knaus EE
J Med Chem; 2006 Mar; 49(5):1668-83. PubMed ID: 16509583
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and biological evaluation of linear phenylethynylbenzenesulfonamide regioisomers as cyclooxygenase-1/-2 (COX-1/-2) inhibitors.
Anana R; Rao PN; Chen QH; Knaus EE
Bioorg Med Chem; 2006 Aug; 14(15):5259-65. PubMed ID: 16635574
[TBL] [Abstract][Full Text] [Related]
15. Design and synthesis of acyclic triaryl (Z)-olefins: a novel class of cyclooxygenase-2 (COX-2) inhibitors.
Uddin MJ; Rao PN; Knaus EE
Bioorg Med Chem; 2004 Nov; 12(22):5929-40. PubMed ID: 15498669
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis and pharmacological evaluation of 4-[2-alkylthio-5(4)-(4-substitutedphenyl)imidazole-4(5)yl]benzenesulfonamides as selective COX-2 inhibitors.
Salimi M; Ghahremani MH; Naderi N; Amini M; Salimi E; Amanlou M; Abdi K; Salehi R; Shafiee A
Acta Pharmacol Sin; 2007 Aug; 28(8):1254-60. PubMed ID: 17640491
[TBL] [Abstract][Full Text] [Related]
17. Synthesis of celecoxib analogs that possess a N-hydroxypyrid-2(1H)one 5-lipoxygenase pharmacophore: biological evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
Chowdhury MA; Abdellatif KR; Dong Y; Das D; Suresh MR; Knaus EE
Bioorg Med Chem Lett; 2008 Dec; 18(23):6138-41. PubMed ID: 18945614
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and biological evaluation of 1,3-diphenylprop-2-en-1-ones possessing a methanesulfonamido or an azido pharmacophore as cyclooxygenase-1/-2 inhibitors.
Zarghi A; Zebardast T; Hakimion F; Shirazi FH; Rao PN; Knaus EE
Bioorg Med Chem; 2006 Oct; 14(20):7044-50. PubMed ID: 16798002
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and biological evaluation of a novel class of rofecoxib analogues as dual inhibitors of cyclooxygenases (COXs) and lipoxygenases (LOXs).
Chen QH; Rao PN; Knaus EE
Bioorg Med Chem; 2006 Dec; 14(23):7898-909. PubMed ID: 16904331
[TBL] [Abstract][Full Text] [Related]
20. Design and synthesis of (Z)-1,2-diphenyl-1-(4-methanesulfonamidophenyl)alk-1-enes and (Z)-1-(4-azidophenyl)-1,2-diphenylalk-1-enes: novel inhibitors of cyclooxygenase-2 (COX-2) with anti-inflammatory and analgesic activity.
Uddin MJ; Praveen Rao PN; Knaus EE
Bioorg Med Chem; 2005 Jan; 13(2):417-24. PubMed ID: 15598562
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
