BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

134 related articles for article (PubMed ID: 17276985)

  • 21. Mechanisms of camptothecin resistance in yeast DNA topoisomerase I mutants.
    Knab AM; Fertala J; Bjornsti MA
    J Biol Chem; 1993 Oct; 268(30):22322-30. PubMed ID: 8226741
    [TBL] [Abstract][Full Text] [Related]  

  • 22. A single mutation in the 729 residue modulates human DNA topoisomerase IB DNA binding and drug resistance.
    Losasso C; Cretaio E; Fiorani P; D'Annessa I; Chillemi G; Benedetti P
    Nucleic Acids Res; 2008 Oct; 36(17):5635-44. PubMed ID: 18772225
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Yeast Saccharomyces cerevisiae as a model system to study the cytotoxic activity of the antitumor drug camptothecin.
    Bjornsti MA; Knab AM; Benedetti P
    Cancer Chemother Pharmacol; 1994; 34 Suppl():S1-5. PubMed ID: 8070016
    [TBL] [Abstract][Full Text] [Related]  

  • 24. A specific transcriptional response of yeast cells to camptothecin dependent on the Swi4 and Mbp1 factors.
    Lotito L; Russo A; Bueno S; Chillemi G; Fogli MV; Capranico G
    Eur J Pharmacol; 2009 Jan; 603(1-3):29-36. PubMed ID: 19094980
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Structural insight of DNA topoisomerases I from camptothecin-producing plants revealed by molecular dynamics simulations.
    Sirikantaramas S; Meeprasert A; Rungrotmongkol T; Fuji H; Hoshino T; Sudo H; Yamazaki M; Saito K
    Phytochemistry; 2015 May; 113():50-6. PubMed ID: 25733498
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Camptothecin resistance from a single mutation changing glycine 363 of human DNA topoisomerase I to cysteine.
    Benedetti P; Fiorani P; Capuani L; Wang JC
    Cancer Res; 1993 Sep; 53(18):4343-8. PubMed ID: 8395982
    [TBL] [Abstract][Full Text] [Related]  

  • 27. A camptothecin-resistant DNA topoisomerase I mutant exhibits altered sensitivities to other DNA topoisomerase poisons.
    Knab AM; Fertala J; Bjornsti MA
    J Biol Chem; 1995 Mar; 270(11):6141-8. PubMed ID: 7890748
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Alterations in the catalytic activity of yeast DNA topoisomerase I result in cell cycle arrest and cell death.
    Megonigal MD; Fertala J; Bjornsti MA
    J Biol Chem; 1997 May; 272(19):12801-8. PubMed ID: 9139740
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The camptothecin-resistant topoisomerase I mutant F361S is cross-resistant to antitumor rebeccamycin derivatives. A model for topoisomerase I inhibition by indolocarbazoles.
    Bailly C; Carrasco C; Hamy F; Vezin H; Prudhomme M; Saleem A; Rubin E
    Biochemistry; 1999 Jul; 38(27):8605-11. PubMed ID: 10393535
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The human DNA topoisomerase I mutant Gly717Asp: Higher religation rate is not always associated with camptothecin resistance.
    Wang Z; D'Annessa I; Tesauro C; Ottaviani A; Soren BC; Dasari JB; Messina B; Thareparambil A; Fiorani P
    Arch Biochem Biophys; 2019 Mar; 663():165-172. PubMed ID: 30653963
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Increased camptothecin toxicity induced in mammalian cells expressing Saccharomyces cerevisiae DNA topoisomerase I.
    Hann C; Evans DL; Fertala J; Benedetti P; Bjornsti MA; Hall DJ
    J Biol Chem; 1998 Apr; 273(14):8425-33. PubMed ID: 9525954
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Mutations in topoisomerase I as a self-resistance mechanism coevolved with the production of the anticancer alkaloid camptothecin in plants.
    Sirikantaramas S; Yamazaki M; Saito K
    Proc Natl Acad Sci U S A; 2008 May; 105(18):6782-6. PubMed ID: 18443285
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Effect of CPT on the DNA cleavage/religation reaction mediated by calf thymus Topoisomerase I: evidence of an inhibition of DNA religation. Inhibition of Topoisomerase I-mediated DNA religation by CPT.
    Carboni MC; Coderoni S
    Mol Biol Rep; 1994-1995; 20(3):129-33. PubMed ID: 7565652
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Evidence that DNA topoisomerase I is necessary for the cytotoxic effects of camptothecin.
    Eng WK; Faucette L; Johnson RK; Sternglanz R
    Mol Pharmacol; 1988 Dec; 34(6):755-60. PubMed ID: 2849043
    [TBL] [Abstract][Full Text] [Related]  

  • 35. SCT1 mutants suppress the camptothecin sensitivity of yeast cells expressing wild-type DNA topoisomerase I.
    Kauh EA; Bjornsti MA
    Proc Natl Acad Sci U S A; 1995 Jul; 92(14):6299-303. PubMed ID: 7603986
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The role of lysine 532 in the catalytic mechanism of human topoisomerase I.
    Interthal H; Quigley PM; Hol WG; Champoux JJ
    J Biol Chem; 2004 Jan; 279(4):2984-92. PubMed ID: 14594810
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Characterization of an altered DNA catalysis of a camptothecin-resistant eukaryotic topoisomerase I.
    Gromova II; Kjeldsen E; Svejstrup JQ; Alsner J; Christiansen K; Westergaard O
    Nucleic Acids Res; 1993 Feb; 21(3):593-600. PubMed ID: 8382801
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The different cleavage DNA sequence specificity explains the camptothecin resistance of the human topoisomerase I Glu418Lys mutant.
    Fiorani P; Chillemi G; Losasso C; Castelli S; Desideri A
    Nucleic Acids Res; 2006; 34(18):5093-100. PubMed ID: 16990249
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Covalent and noncovalent DNA binding by mutants of vaccinia DNA topoisomerase I.
    Morham SG; Shuman S
    J Biol Chem; 1992 Aug; 267(22):15984-92. PubMed ID: 1322412
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Global transcription regulation by DNA topoisomerase I in exponentially growing Saccharomyces cerevisiae cells: activation of telomere-proximal genes by TOP1 deletion.
    Lotito L; Russo A; Chillemi G; Bueno S; Cavalieri D; Capranico G
    J Mol Biol; 2008 Mar; 377(2):311-22. PubMed ID: 18272174
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.