181 related articles for article (PubMed ID: 17279612)
1. Electrostatic contributions to binding of transition state analogues can be very different from the corresponding contributions to catalysis: phenolates binding to the oxyanion hole of ketosteroid isomerase.
Warshel A; Sharma PK; Chu ZT; Aqvist J
Biochemistry; 2007 Feb; 46(6):1466-76. PubMed ID: 17279612
[TBL] [Abstract][Full Text] [Related]
2. Testing electrostatic complementarity in enzyme catalysis: hydrogen bonding in the ketosteroid isomerase oxyanion hole.
Kraut DA; Sigala PA; Pybus B; Liu CW; Ringe D; Petsko GA; Herschlag D
PLoS Biol; 2006 Apr; 4(4):e99. PubMed ID: 16602823
[TBL] [Abstract][Full Text] [Related]
3. Ketosteroid isomerase provides further support for the idea that enzymes work by electrostatic preorganization.
Kamerlin SC; Sharma PK; Chu ZT; Warshel A
Proc Natl Acad Sci U S A; 2010 Mar; 107(9):4075-80. PubMed ID: 20150513
[TBL] [Abstract][Full Text] [Related]
4. Using unnatural amino acids to probe the energetics of oxyanion hole hydrogen bonds in the ketosteroid isomerase active site.
Natarajan A; Schwans JP; Herschlag D
J Am Chem Soc; 2014 May; 136(21):7643-54. PubMed ID: 24787954
[TBL] [Abstract][Full Text] [Related]
5. Testing geometrical discrimination within an enzyme active site: constrained hydrogen bonding in the ketosteroid isomerase oxyanion hole.
Sigala PA; Kraut DA; Caaveiro JM; Pybus B; Ruben EA; Ringe D; Petsko GA; Herschlag D
J Am Chem Soc; 2008 Oct; 130(41):13696-708. PubMed ID: 18808119
[TBL] [Abstract][Full Text] [Related]
6. Evaluating the catalytic contribution from the oxyanion hole in ketosteroid isomerase.
Schwans JP; Sunden F; Gonzalez A; Tsai Y; Herschlag D
J Am Chem Soc; 2011 Dec; 133(50):20052-5. PubMed ID: 22053826
[TBL] [Abstract][Full Text] [Related]
7. A Preorganized Electric Field Leads to Minimal Geometrical Reorientation in the Catalytic Reaction of Ketosteroid Isomerase.
Wu Y; Fried SD; Boxer SG
J Am Chem Soc; 2020 Jun; 142(22):9993-9998. PubMed ID: 32378409
[TBL] [Abstract][Full Text] [Related]
8. A Critical Test of the Electrostatic Contribution to Catalysis with Noncanonical Amino Acids in Ketosteroid Isomerase.
Wu Y; Boxer SG
J Am Chem Soc; 2016 Sep; 138(36):11890-5. PubMed ID: 27545569
[TBL] [Abstract][Full Text] [Related]
9. The catalytic power of ketosteroid isomerase investigated by computer simulation.
Feierberg I; Aqvist J
Biochemistry; 2002 Dec; 41(52):15728-35. PubMed ID: 12501201
[TBL] [Abstract][Full Text] [Related]
10. Determining the catalytic role of remote substrate binding interactions in ketosteroid isomerase.
Schwans JP; Kraut DA; Herschlag D
Proc Natl Acad Sci U S A; 2009 Aug; 106(34):14271-5. PubMed ID: 19706511
[TBL] [Abstract][Full Text] [Related]
11. Molecular dynamics and quantum chemical studies on the catalytic mechanism of Delta5-3-ketosteroid isomerase: the catalytic diad versus the cooperative hydrogen bond mechanism.
Park H; Merz KM
J Am Chem Soc; 2003 Jan; 125(4):901-11. PubMed ID: 12537487
[TBL] [Abstract][Full Text] [Related]
12. Charge Density in Enzyme Active Site as a Descriptor of Electrostatic Preorganization.
Fuller J; Wilson TR; Eberhart ME; Alexandrova AN
J Chem Inf Model; 2019 May; 59(5):2367-2373. PubMed ID: 30793899
[TBL] [Abstract][Full Text] [Related]
13. Proton affinity of the oxyanion hole in the active site of ketosteroid isomerase.
Childs W; Boxer SG
Biochemistry; 2010 Mar; 49(12):2725-31. PubMed ID: 20143849
[TBL] [Abstract][Full Text] [Related]
14. Evaluating the potential for halogen bonding in the oxyanion hole of ketosteroid isomerase using unnatural amino acid mutagenesis.
Kraut DA; Churchill MJ; Dawson PE; Herschlag D
ACS Chem Biol; 2009 Apr; 4(4):269-73. PubMed ID: 19260691
[TBL] [Abstract][Full Text] [Related]
15. Contribution of a low-barrier hydrogen bond to catalysis is not significant in ketosteroid isomerase.
Jang DS; Choi G; Cha HJ; Shin S; Hong BH; Lee HJ; Lee HC; Choi KY
Mol Cells; 2015 May; 38(5):409-15. PubMed ID: 25947291
[TBL] [Abstract][Full Text] [Related]
16. Structure and enzymology of Delta5-3-ketosteroid isomerase.
Ha NC; Choi G; Choi KY; Oh BH
Curr Opin Struct Biol; 2001 Dec; 11(6):674-8. PubMed ID: 11751047
[TBL] [Abstract][Full Text] [Related]
17. Evaluation of the Catalytic Contribution from a Positioned General Base in Ketosteroid Isomerase.
Lamba V; Yabukarski F; Pinney M; Herschlag D
J Am Chem Soc; 2016 Aug; 138(31):9902-9. PubMed ID: 27410422
[TBL] [Abstract][Full Text] [Related]
18. Structural double-mutant cycle analysis of a hydrogen bond network in ketosteroid isomerase from Pseudomonas putida biotype B.
Jang DS; Cha HJ; Cha SS; Hong BH; Ha NC; Lee JY; Oh BH; Lee HS; Choi KY
Biochem J; 2004 Sep; 382(Pt 3):967-73. PubMed ID: 15228388
[TBL] [Abstract][Full Text] [Related]
19. Extreme electric fields power catalysis in the active site of ketosteroid isomerase.
Fried SD; Bagchi S; Boxer SG
Science; 2014 Dec; 346(6216):1510-4. PubMed ID: 25525245
[TBL] [Abstract][Full Text] [Related]
20. Crystal structure and enzyme mechanism of Delta 5-3-ketosteroid isomerase from Pseudomonas testosteroni.
Cho HS; Choi G; Choi KY; Oh BH
Biochemistry; 1998 Jun; 37(23):8325-30. PubMed ID: 9622484
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]