BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

323 related articles for article (PubMed ID: 17286393)

  • 1. Potent antitubulin tumor cell cytotoxins based on 3-aroyl indazoles.
    Duan JX; Cai X; Meng F; Lan L; Hart C; Matteucci M
    J Med Chem; 2007 Mar; 50(5):1001-6. PubMed ID: 17286393
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 7-Aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents.
    Chang JY; Hsieh HP; Chang CY; Hsu KS; Chiang YF; Chen CM; Kuo CC; Liou JP
    J Med Chem; 2006 Nov; 49(23):6656-9. PubMed ID: 17154496
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 4- and 5-aroylindoles as novel classes of potent antitubulin agents.
    Liou JP; Wu CY; Hsieh HP; Chang CY; Chen CM; Kuo CC; Chang JY
    J Med Chem; 2007 Sep; 50(18):4548-52. PubMed ID: 17685504
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
    Chang JY; Yang MF; Chang CY; Chen CM; Kuo CC; Liou JP
    J Med Chem; 2006 Oct; 49(21):6412-5. PubMed ID: 17034147
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sulfonate derivatives of naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-anthracenone as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A; Schmidt P; Baasner S; Böhm KJ; Müller K; Gerlach M; Günther EG; Unger E; Prinz H
    J Med Chem; 2007 Nov; 50(24):6059-66. PubMed ID: 17973361
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.
    Romagnoli R; Baraldi PG; Pavani MG; Tabrizi MA; Preti D; Fruttarolo F; Piccagli L; Jung MK; Hamel E; Borgatti M; Gambari R
    J Med Chem; 2006 Jun; 49(13):3906-15. PubMed ID: 16789746
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A; Schmidt P; Baasner S; Böhm KJ; Müller K; Gerlach M; Günther EG; Unger E; Prinz H
    J Med Chem; 2006 Dec; 49(26):7816-25. PubMed ID: 17181164
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 10-(2-oxo-2-phenylethylidene)-10H-anthracen-9-ones as highly active antimicrotubule agents: synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Prinz H; Schmidt P; Böhm KJ; Baasner S; Müller K; Unger E; Gerlach M; Günther EG
    J Med Chem; 2009 Mar; 52(5):1284-94. PubMed ID: 19220018
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studies.
    La Regina G; Edler MC; Brancale A; Kandil S; Coluccia A; Piscitelli F; Hamel E; De Martino G; Matesanz R; Díaz JF; Scovassi AI; Prosperi E; Lavecchia A; Novellino E; Artico M; Silvestri R
    J Med Chem; 2007 Jun; 50(12):2865-74. PubMed ID: 17497841
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [4-(imidazol-1-yl)thiazol-2-yl]phenylamines. A novel class of highly potent colchicine site binding tubulin inhibitors: synthesis and cytotoxic activity on selected human cancer cell lines.
    Mahboobi S; Sellmer A; Höcher H; Eichhorn E; Bär T; Schmidt M; Maier T; Stadlwieser JF; Beckers TL
    J Med Chem; 2006 Sep; 49(19):5769-76. PubMed ID: 16970401
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 2-amino-3,4,5-trimethoxybenzophenones as potent tubulin polymerization inhibitors.
    Chuang HY; Chang JY; Lai MJ; Kuo CC; Lee HY; Hsieh HP; Chen YJ; Chen LT; Pan WY; Liou JP
    ChemMedChem; 2011 Mar; 6(3):450-6. PubMed ID: 21360819
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agents.
    O'Boyle NM; Carr M; Greene LM; Bergin O; Nathwani SM; McCabe T; Lloyd DG; Zisterer DM; Meegan MJ
    J Med Chem; 2010 Dec; 53(24):8569-84. PubMed ID: 21080725
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, biological evaluation and molecular docking studies of resveratrol derivatives possessing curcumin moiety as potent antitubulin agents.
    Ruan BF; Lu X; Li TT; Tang JF; Wei Y; Wang XL; Zheng SL; Yao RS; Zhu HL
    Bioorg Med Chem; 2012 Jan; 20(2):1113-21. PubMed ID: 22189271
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.
    Romagnoli R; Baraldi PG; Carrion MD; Lopez Cara C; Preti D; Fruttarolo F; Pavani MG; Tabrizi MA; Tolomeo M; Grimaudo S; Di Cristina A; Balzarini J; Hadfield JA; Brancale A; Hamel E
    J Med Chem; 2007 May; 50(9):2273-7. PubMed ID: 17419607
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents.
    Reddy GR; Kuo CC; Tan UK; Coumar MS; Chang CY; Chiang YK; Lai MJ; Yeh JY; Wu SY; Chang JY; Liou JP; Hsieh HP
    J Med Chem; 2008 Dec; 51(24):8163-7. PubMed ID: 19053773
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and antitumor activity of benzils related to combretastatin A-4.
    Mousset C; Giraud A; Provot O; Hamze A; Bignon J; Liu JM; Thoret S; Dubois J; Brion JD; Alami M
    Bioorg Med Chem Lett; 2008 Jun; 18(11):3266-71. PubMed ID: 18477509
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regioselective Suzuki coupling of dihaloheteroaromatic compounds as a rapid strategy to synthesize potent rigid combretastatin analogues.
    Theeramunkong S; Caldarelli A; Massarotti A; Aprile S; Caprioglio D; Zaninetti R; Teruggi A; Pirali T; Grosa G; Tron GC; Genazzani AA
    J Med Chem; 2011 Jul; 54(14):4977-86. PubMed ID: 21696175
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors. Part 2. The impact of bridging groups at position C-2.
    Lee HY; Chang JY; Nien CY; Kuo CC; Shih KH; Wu CH; Chang CY; Lai WY; Liou JP
    J Med Chem; 2011 Dec; 54(24):8517-25. PubMed ID: 22060033
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Integration of ligand and structure-based virtual screening for the identification of the first dual targeting agent for heat shock protein 90 (Hsp90) and tubulin.
    Knox AJ; Price T; Pawlak M; Golfis G; Flood CT; Fayne D; Williams DC; Meegan MJ; Lloyd DG
    J Med Chem; 2009 Apr; 52(8):2177-80. PubMed ID: 19331414
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New antitubulin derivatives in the combretastatin A4 series: synthesis and biological evaluation.
    Borrel C; Thoret S; Cachet X; Guénard D; Tillequin F; Koch M; Michel S
    Bioorg Med Chem; 2005 Jun; 13(11):3853-64. PubMed ID: 15863010
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.