BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 17287337)

  • 1. Therapeutic anticancer efficacy of a synthetic diazonamide analog in the absence of overt toxicity.
    Williams NS; Burgett AW; Atkins AS; Wang X; Harran PG; McKnight SL
    Proc Natl Acad Sci U S A; 2007 Feb; 104(7):2074-9. PubMed ID: 17287337
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Diazonamide A and a synthetic structural analog: disruptive effects on mitosis and cellular microtubules and analysis of their interactions with tubulin.
    Cruz-Monserrate Z; Vervoort HC; Bai R; Newman DJ; Howell SB; Los G; Mullaney JT; Williams MD; Pettit GR; Fenical W; Hamel E
    Mol Pharmacol; 2003 Jun; 63(6):1273-80. PubMed ID: 12761336
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Diazonamide toxins reveal an unexpected function for ornithine delta-amino transferase in mitotic cell division.
    Wang G; Shang L; Burgett AW; Harran PG; Wang X
    Proc Natl Acad Sci U S A; 2007 Feb; 104(7):2068-73. PubMed ID: 17287350
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity.
    Wieczorek M; Tcherkezian J; Bernier C; Prota AE; Chaaban S; Rolland Y; Godbout C; Hancock MA; Arezzo JC; Ocal O; Rocha C; Olieric N; Hall A; Ding H; Bramoullé A; Annis MG; Zogopoulos G; Harran PG; Wilkie TM; Brekken RA; Siegel PM; Steinmetz MO; Shore GC; Brouhard GJ; Roulston A
    Sci Transl Med; 2016 Nov; 8(365):365ra159. PubMed ID: 27856798
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chemistry and biology of diazonamide A: second total synthesis and biological investigations.
    Nicolaou KC; Hao J; Reddy MV; Rao PB; Rassias G; Snyder SA; Huang X; Chen DY; Brenzovich WE; Giuseppone N; O'Brate A; Giannakakou P
    J Am Chem Soc; 2004 Oct; 126(40):12897-906. PubMed ID: 15469287
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interaction of diazonamide A with tubulin.
    Bai R; Cruz-Monserrate Z; Fenical W; Pettit GR; Hamel E
    Arch Biochem Biophys; 2020 Feb; 680():108217. PubMed ID: 31830440
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Towards modern anticancer agents that interact with tubulin.
    La Regina G; Coluccia A; Naccarato V; Silvestri R
    Eur J Pharm Sci; 2019 Apr; 131():58-68. PubMed ID: 30690185
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanisms of action and resistance to tubulin-binding agents.
    Dumontet C
    Expert Opin Investig Drugs; 2000 Apr; 9(4):779-88. PubMed ID: 11060709
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tolerated doses in zebrafish of cytochalasins and jasplakinolide for comparison with tolerated doses in mice in the evaluation of pre-clinical activity of microfilament-directed agents in tumor model systems in vivo.
    Trendowski M; Wong V; Wellington K; Hatfield S; Fondy TP
    In Vivo; 2014; 28(6):1021-31. PubMed ID: 25398795
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tubulin: a target for antineoplastic drugs into the cancer cells but also in the peripheral nervous system.
    Canta A; Chiorazzi A; Cavaletti G
    Curr Med Chem; 2009; 16(11):1315-24. PubMed ID: 19355888
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dolastatin 15 binds in the vinca domain of tubulin as demonstrated by Hummel-Dreyer chromatography.
    Cruz-Monserrate Z; Mullaney JT; Harran PG; Pettit GR; Hamel E
    Eur J Biochem; 2003 Sep; 270(18):3822-8. PubMed ID: 12950266
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanisms of action of and resistance to antitubulin agents: microtubule dynamics, drug transport, and cell death.
    Dumontet C; Sikic BI
    J Clin Oncol; 1999 Mar; 17(3):1061-70. PubMed ID: 10071301
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Taxanes in cancer treatment: Activity, chemoresistance and its overcoming.
    Mosca L; Ilari A; Fazi F; Assaraf YG; Colotti G
    Drug Resist Updat; 2021 Jan; 54():100742. PubMed ID: 33429249
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Natural products as antimitotic agents.
    Dall'Acqua S
    Curr Top Med Chem; 2014; 14(20):2272-85. PubMed ID: 25434355
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Microtubule Targeting Agents as Cancer Chemotherapeutics: An Overview of Molecular Hybrids as Stabilizing and Destabilizing Agents.
    Tangutur AD; Kumar D; Krishna KV; Kantevari S
    Curr Top Med Chem; 2017; 17(22):2523-2537. PubMed ID: 28056738
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Microtubulin binding sites as target for developing anticancer agents.
    Islam MN; Iskander MN
    Mini Rev Med Chem; 2004 Dec; 4(10):1077-104. PubMed ID: 15579115
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel aspects of natural and modified vinca alkaloids.
    Duflos A; Kruczynski A; Barret JM
    Curr Med Chem Anticancer Agents; 2002 Jan; 2(1):55-70. PubMed ID: 12678751
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Anticancer therapy with novel tubulin-interacting drugs.
    Kavallaris M; Verrills NM; Hill BT
    Drug Resist Updat; 2001 Dec; 4(6):392-401. PubMed ID: 12030786
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Natural products as new antimitotic compounds for anticancer drug development.
    Paier CRK; Maranhão SS; Carneiro TR; Lima LM; Rocha DD; Santos RDS; Farias KM; Moraes-Filho MO; Pessoa C
    Clinics (Sao Paulo); 2018 Dec; 73(suppl 1):e813s. PubMed ID: 30540125
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Advances in vinca-alkaloids: Navelbine.
    Marty M; Extra JM; Espie M; Leandri S; Besenval M; Krikorian A
    Nouv Rev Fr Hematol (1978); 1989; 31(2):77-84. PubMed ID: 2671933
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.