These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

121 related articles for article (PubMed ID: 17289388)

  • 1. Evaluation of the anti-hepatitis C virus effect of novel potent, selective, and orally bioavailable JNK and VEGFR kinase inhibitors.
    Raboisson P; Lenz O; Lin TI; Surleraux D; Chakravarty S; Scholliers A; Vermeiren K; Delouvroy F; Verbinnen T; Simmen K
    Bioorg Med Chem Lett; 2007 Apr; 17(7):1843-9. PubMed ID: 17289388
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Studies on acyl pyrrolidine inhibitors of HCV RNA-dependent RNA polymerase to identify a molecule with replicon antiviral activity.
    Burton G; Ku TW; Carr TJ; Kiesow T; Sarisky RT; Lin-Goerke J; Hofmann GA; Slater MJ; Haigh D; Dhanak D; Johnson VK; Parry NR; Thommes P
    Bioorg Med Chem Lett; 2007 Apr; 17(7):1930-3. PubMed ID: 17270443
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of the aryl linker and the aromatic substituent on the anti-HCV activities of aryl diketoacid (ADK) analogues.
    Kim J; Kim KS; Lee HS; Park KS; Park SY; Kang SY; Lee SJ; Park HS; Kim DE; Chong Y
    Bioorg Med Chem Lett; 2008 Aug; 18(16):4661-5. PubMed ID: 18644717
    [TBL] [Abstract][Full Text] [Related]  

  • 4. HCV NS5B polymerase inhibitors 3: Synthesis and in vitro activity of 3-(1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl)-4-hydroxy-2H-quinolizin-2-one derivatives.
    Wang G; Zhang L; Wu X; Das D; Ruhrmund D; Hooi L; Misialek S; Ravi Rajagopalan PT; Buckman BO; Kossen K; Seiwert SD; Beigelman L
    Bioorg Med Chem Lett; 2009 Aug; 19(15):4484-7. PubMed ID: 19497737
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HCV NS5B polymerase inhibitors 2: Synthesis and in vitro activity of (1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl) azolo[1,5-a]pyridine and azolo[1,5-a]pyrimidine derivatives.
    Wang G; Lei H; Wang X; Das D; Hong J; Mackinnon CH; Coulter TS; Montalbetti CA; Mears R; Gai X; Bailey SE; Ruhrmund D; Hooi L; Misialek S; Rajagopalan PT; Cheng RK; Barker JJ; Felicetti B; Schönfeld DL; Stoycheva A; Buckman BO; Kossen K; Seiwert SD; Beigelman L
    Bioorg Med Chem Lett; 2009 Aug; 19(15):4480-3. PubMed ID: 19500983
    [TBL] [Abstract][Full Text] [Related]  

  • 6. HCV NS5B polymerase inhibitors 1: Synthesis and in vitro activity of 2-(1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl)-1-hydroxynaphthalene derivatives.
    Wang G; He Y; Sun J; Das D; Hu M; Huang J; Ruhrmund D; Hooi L; Misialek S; Ravi Rajagopalan PT; Stoycheva A; Buckman BO; Kossen K; Seiwert SD; Beigelman L
    Bioorg Med Chem Lett; 2009 Aug; 19(15):4476-9. PubMed ID: 19502055
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 1,5-Benzodiazepine inhibitors of HCV NS5B polymerase.
    McGowan D; Nyanguile O; Cummings MD; Vendeville S; Vandyck K; Van den Broeck W; Boutton CW; De Bondt H; Quirynen L; Amssoms K; Bonfanti JF; Last S; Rombauts K; Tahri A; Hu L; Delouvroy F; Vermeiren K; Vandercruyssen G; Van der Helm L; Cleiren E; Mostmans W; Lory P; Pille G; Van Emelen K; Fanning G; Pauwels F; Lin TI; Simmen K; Raboisson P
    Bioorg Med Chem Lett; 2009 May; 19(9):2492-6. PubMed ID: 19342234
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Substituted benzothiadizine inhibitors of Hepatitis C virus polymerase.
    Shaw AN; Tedesco R; Bambal R; Chai D; Concha NO; Darcy MG; Dhanak D; Duffy KJ; Fitch DM; Gates A; Johnston VK; Keenan RM; Lin-Goerke J; Liu N; Sarisky RT; Wiggall KJ; Zimmerman MN
    Bioorg Med Chem Lett; 2009 Aug; 19(15):4350-3. PubMed ID: 19515564
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphorous acid analogs of novel P2-P4 macrocycles as inhibitors of HCV-NS3 protease.
    Pompei M; Francesco ME; Koch U; Liverton NJ; Summa V
    Bioorg Med Chem Lett; 2009 May; 19(9):2574-8. PubMed ID: 19328685
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 3-heterocyclyl quinolone inhibitors of the HCV NS5B polymerase.
    Kumar DV; Rai R; Brameld KA; Riggs J; Somoza JR; Rajagopalan R; Janc JW; Xia YM; Ton TL; Hu H; Lehoux I; Ho JD; Young WB; Hart B; Green MJ
    Bioorg Med Chem Lett; 2012 Jan; 22(1):300-4. PubMed ID: 22119470
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 6-Hydrazinopurine 2'-methyl ribonucleosides and their 5'-monophosphate prodrugs as potent hepatitis C virus inhibitors.
    Gunic E; Chow S; Rong F; Ramasamy K; Raney A; Li DY; Huang J; Hamatake RK; Hong Z; Girardet JL
    Bioorg Med Chem Lett; 2007 May; 17(9):2456-8. PubMed ID: 17331718
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hepatitis C NS5B polymerase inhibitors: 4,4-Dialkyl-1-hydroxy-3-oxo-3,4-dihydronaphthalene-3-yl benzothiadiazine derivatives.
    Hutchinson DK; Rosenberg T; Klein LL; Bosse TD; Larson DP; He W; Jiang WW; Kati WM; Kohlbrenner WE; Liu Y; Masse SV; Middleton T; Molla A; Montgomery DA; Beno DW; Stewart KD; Stoll VS; Kempf DJ
    Bioorg Med Chem Lett; 2008 Jul; 18(14):3887-90. PubMed ID: 18599294
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design and synthesis of indole, 2,3-dihydro-indole, and 3,4-dihydro-2H-quinoline-1-carbothioic acid amide derivatives as novel HCV inhibitors.
    Kang IJ; Wang LW; Hsu SJ; Lee CC; Lee YC; Wu YS; Hsu TA; Yueh A; Chao YS; Chern JH
    Bioorg Med Chem Lett; 2009 Aug; 19(15):4134-8. PubMed ID: 19539472
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The application of phosphoramidate ProTide technology to the potent anti-HCV compound 4'-azidocytidine (R1479).
    McGuigan C; Kelleher MR; Perrone P; Mulready S; Luoni G; Daverio F; Rajyaguru S; Le Pogam S; Najera I; Martin JA; Klumpp K; Smith DB
    Bioorg Med Chem Lett; 2009 Aug; 19(15):4250-4. PubMed ID: 19505826
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological activity of heteroaryl 3-(1,1-dioxo-2H-(1,2,4)-benzothiadizin-3-yl)-4-hydroxy-2(1H)-quinolinone derivatives as hepatitis C virus NS5B polymerase inhibitors.
    Tedesco R; Chai D; Darcy MG; Dhanak D; Fitch DM; Gates A; Johnston VK; Keenan RM; Lin-Goerke J; Sarisky RT; Shaw AN; Valko KL; Wiggall KJ; Zimmerman MN; Duffy KJ
    Bioorg Med Chem Lett; 2009 Aug; 19(15):4354-8. PubMed ID: 19505821
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure-based design, synthesis, and biological evaluation of 1,1-dioxoisothiazole and benzo[b]thiophene-1,1-dioxide derivatives as novel inhibitors of hepatitis C virus NS5B polymerase.
    Kim SH; Tran MT; Ruebsam F; Xiang AX; Ayida B; McGuire H; Ellis D; Blazel J; Tran CV; Murphy DE; Webber SE; Zhou Y; Shah AM; Tsan M; Showalter RE; Patel R; Gobbi A; LeBrun LA; Bartkowski DM; Nolan TG; Norris DA; Sergeeva MV; Kirkovsky L; Zhao Q; Han Q; Kissinger CR
    Bioorg Med Chem Lett; 2008 Jul; 18(14):4181-5. PubMed ID: 18554907
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Induced oxidative stress and activated expression of manganese superoxide dismutase during hepatitis C virus replication: role of JNK, p38 MAPK and AP-1.
    Qadri I; Iwahashi M; Capasso JM; Hopken MW; Flores S; Schaack J; Simon FR
    Biochem J; 2004 Mar; 378(Pt 3):919-28. PubMed ID: 14670077
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cyclic monophosphate prodrugs of base-modified 2'-C-methyl ribonucleosides as potent inhibitors of hepatitis C virus RNA replication.
    Gunic E; Girardet JL; Ramasamy K; Stoisavljevic-Petkov V; Chow S; Yeh LT; Hamatake RK; Raney A; Hong Z
    Bioorg Med Chem Lett; 2007 May; 17(9):2452-5. PubMed ID: 17331721
    [TBL] [Abstract][Full Text] [Related]  

  • 19. C-6 aryl substituted 4-quinolone-3-carboxylic acids as inhibitors of hepatitis C virus.
    Chen YL; Zacharias J; Vince R; Geraghty RJ; Wang Z
    Bioorg Med Chem; 2012 Aug; 20(15):4790-800. PubMed ID: 22748708
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The use of chemical double-mutant cycles in biomolecular recognition studies: application to HCV NS3 protease inhibitors.
    Kawai SH; Bailey MD; Halmos T; Forgione P; Laplante SR; Llinàs-Brunet M; Naud J; Goudreau N
    ChemMedChem; 2008 Nov; 3(11):1654-7. PubMed ID: 18942693
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 7.