BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

804 related articles for article (PubMed ID: 17289593)

  • 1. Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase.
    Kubicek S; O'Sullivan RJ; August EM; Hickey ER; Zhang Q; Teodoro ML; Rea S; Mechtler K; Kowalski JA; Homon CA; Kelly TA; Jenuwein T
    Mol Cell; 2007 Feb; 25(3):473-81. PubMed ID: 17289593
    [TBL] [Abstract][Full Text] [Related]  

  • 2. IVMBIX-01294, an inhibitor of the histone methyltransferase EHMT2, disrupts histone H3 lysine 9 (H3K9) dimethylation in the cleavage-stage porcine embryo.
    Park KE; Johnson CM; Cabot RA
    Reprod Fertil Dev; 2012; 24(6):813-21. PubMed ID: 22781932
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effect of BIX-01294 on H3K9me2 levels and the imprinted gene Snrpn in mouse embryonic fibroblast cells.
    Chen P; Yao JF; Huang RF; Zheng FF; Jiang XH; Chen X; Chen J; Li M; Huang HF; Jiang YP; Huang YF; Yang XY
    Biosci Rep; 2015 Aug; 35(5):. PubMed ID: 26285804
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sequence specificity and role of proximal amino acids of the histone H3 tail on catalysis of murine G9A lysine 9 histone H3 methyltransferase.
    Chin HG; Pradhan M; Estève PO; Patnaik D; Evans TC; Pradhan S
    Biochemistry; 2005 Oct; 44(39):12998-3006. PubMed ID: 16185068
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Histone lysine methyltransferase G9a is a novel epigenetic target for the treatment of hepatocellular carcinoma.
    Yokoyama M; Chiba T; Zen Y; Oshima M; Kusakabe Y; Noguchi Y; Yuki K; Koide S; Tara S; Saraya A; Aoyama K; Mimura N; Miyagi S; Inoue M; Wakamatsu T; Saito T; Ogasawara S; Suzuki E; Ooka Y; Tawada A; Otsuka M; Miyazaki M; Yokosuka O; Iwama A
    Oncotarget; 2017 Mar; 8(13):21315-21326. PubMed ID: 28423509
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Beneficial effects of diazepin-quinazolin-amine derivative (BIX-01294) on preimplantation development and molecular characteristics of cloned mouse embryos.
    Huang Y; Jiang X; Yu M; Huang R; Yao J; Li M; Zheng F; Yang X
    Reprod Fertil Dev; 2017 Jun; 29(6):1260-1269. PubMed ID: 27477633
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Methylation of a histone mimic within the histone methyltransferase G9a regulates protein complex assembly.
    Sampath SC; Marazzi I; Yap KL; Sampath SC; Krutchinsky AN; Mecklenbräuker I; Viale A; Rudensky E; Zhou MM; Chait BT; Tarakhovsky A
    Mol Cell; 2007 Aug; 27(4):596-608. PubMed ID: 17707231
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Histone methyltransferase G9a and H3K9 dimethylation inhibit the self-renewal of glioma cancer stem cells.
    Tao H; Li H; Su Y; Feng D; Wang X; Zhang C; Ma H; Hu Q
    Mol Cell Biochem; 2014 Sep; 394(1-2):23-30. PubMed ID: 24833465
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Catalytic properties and kinetic mechanism of human recombinant Lys-9 histone H3 methyltransferase SUV39H1: participation of the chromodomain in enzymatic catalysis.
    Chin HG; Patnaik D; Estève PO; Jacobsen SE; Pradhan S
    Biochemistry; 2006 Mar; 45(10):3272-84. PubMed ID: 16519522
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Functional dynamics of H3K9 methylation during meiotic prophase progression.
    Tachibana M; Nozaki M; Takeda N; Shinkai Y
    EMBO J; 2007 Jul; 26(14):3346-59. PubMed ID: 17599069
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hypoxic stress induces dimethylated histone H3 lysine 9 through histone methyltransferase G9a in mammalian cells.
    Chen H; Yan Y; Davidson TL; Shinkai Y; Costa M
    Cancer Res; 2006 Sep; 66(18):9009-16. PubMed ID: 16982742
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genome-wide and locus-specific DNA hypomethylation in G9a deficient mouse embryonic stem cells.
    Ikegami K; Iwatani M; Suzuki M; Tachibana M; Shinkai Y; Tanaka S; Greally JM; Yagi S; Hattori N; Shiota K
    Genes Cells; 2007 Jan; 12(1):1-11. PubMed ID: 17212651
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294.
    Chang Y; Zhang X; Horton JR; Upadhyay AK; Spannhoff A; Liu J; Snyder JP; Bedford MT; Cheng X
    Nat Struct Mol Biol; 2009 Mar; 16(3):312-7. PubMed ID: 19219047
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum.
    Malmquist NA; Moss TA; Mecheri S; Scherf A; Fuchter MJ
    Proc Natl Acad Sci U S A; 2012 Oct; 109(41):16708-13. PubMed ID: 23011794
    [TBL] [Abstract][Full Text] [Related]  

  • 15. G9a-mediated histone methylation regulates cadmium-induced male fertility damage in pubertal mice.
    Li M; Liu C; Yang L; Zhang L; Chen C; He M; Lu Y; Feng W; Pi H; Zhang Y; Zhong M; Yu Z; Zhou Z
    Toxicol Lett; 2016 Jun; 252():11-21. PubMed ID: 27060504
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional role of G9a-induced histone methylation in small heterodimer partner-mediated transcriptional repression.
    Boulias K; Talianidis I
    Nucleic Acids Res; 2004; 32(20):6096-103. PubMed ID: 15550569
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Chromatin flow cytometry identifies changes in epigenetic cell states.
    Obier N; Müller AM
    Cells Tissues Organs; 2010; 191(3):167-74. PubMed ID: 19776550
    [TBL] [Abstract][Full Text] [Related]  

  • 18. G9a/GLP histone lysine dimethyltransferase complex activity in the hippocampus and the entorhinal cortex is required for gene activation and silencing during memory consolidation.
    Gupta-Agarwal S; Franklin AV; Deramus T; Wheelock M; Davis RL; McMahon LL; Lubin FD
    J Neurosci; 2012 Apr; 32(16):5440-53. PubMed ID: 22514307
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of H3K9 histone methyltransferase G9a attenuates renal fibrosis and retains klotho expression.
    Irifuku T; Doi S; Sasaki K; Doi T; Nakashima A; Ueno T; Yamada K; Arihiro K; Kohno N; Masaki T
    Kidney Int; 2016 Jan; 89(1):147-57. PubMed ID: 26444031
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A continuous protein methyltransferase (G9a) assay for enzyme activity measurement and inhibitor screening.
    Dhayalan A; Dimitrova E; Rathert P; Jeltsch A
    J Biomol Screen; 2009 Oct; 14(9):1129-33. PubMed ID: 19734436
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 41.