88 related articles for article (PubMed ID: 17290608)
1. [Gamma-Schisandrin inhibits production of amyloid beta-protein 42 in M146L cells].
Liu W; Yu R; Wu JH; Luo HM
Yao Xue Xue Bao; 2006 Dec; 41(12):1136-40. PubMed ID: 17290608
[TBL] [Abstract][Full Text] [Related]
2. Reduction of Aβ Generation by Schisandrin B through Restraining Beta-Secretase 1 Transcription and Translation.
Li Z; Liu XC; Li R; Chang J
Med Sci Monit; 2018 Feb; 24():1219-1224. PubMed ID: 29487280
[TBL] [Abstract][Full Text] [Related]
3. Biochemical characterization of the gamma-secretase activity that produces beta-amyloid peptides.
Zhang L; Song L; Terracina G; Liu Y; Pramanik B; Parker E
Biochemistry; 2001 Apr; 40(16):5049-55. PubMed ID: 11305921
[TBL] [Abstract][Full Text] [Related]
4. CTF1-51, a truncated carboxyl-terminal fragment of amyloid precursor protein, suppresses the effects of Aβ42-lowering γ-secretase modulators.
Watahiki H; Yagishita S; Futai E; Ishiura S
Neurosci Lett; 2012 Sep; 526(2):96-9. PubMed ID: 22940081
[TBL] [Abstract][Full Text] [Related]
5. Synthetic ceramide analogues increase amyloid-β 42 production by modulating γ-secretase activity.
Takasugi N; Sasaki T; Shinohara M; Iwatsubo T; Tomita T
Biochem Biophys Res Commun; 2015 Feb; 457(2):194-9. PubMed ID: 25545059
[TBL] [Abstract][Full Text] [Related]
6. Geranylgeranyl pyrophosphate stimulates gamma-secretase to increase the generation of Abeta and APP-CTFgamma.
Zhou Y; Suram A; Venugopal C; Prakasam A; Lin S; Su Y; Li B; Paul SM; Sambamurti K
FASEB J; 2008 Jan; 22(1):47-54. PubMed ID: 17666454
[TBL] [Abstract][Full Text] [Related]
7. Phenylpropanoids from cinnamon bark reduced β-amyloid production by the inhibition of β-secretase in Chinese hamster ovarian cells stably expressing amyloid precursor protein.
Kang YJ; Seo DG; Park SY
Nutr Res; 2016 Nov; 36(11):1277-1284. PubMed ID: 27865616
[TBL] [Abstract][Full Text] [Related]
8. The A673T mutation in the amyloid precursor protein reduces the production of β-amyloid protein from its β-carboxyl terminal fragment in cells.
Kokawa A; Ishihara S; Fujiwara H; Nobuhara M; Iwata M; Ihara Y; Funamoto S
Acta Neuropathol Commun; 2015 Nov; 3():66. PubMed ID: 26531305
[TBL] [Abstract][Full Text] [Related]
9. Schisandrin B protects rat cortical neurons against Abeta1-42-induced neurotoxicity.
Wang B; Wang XM
Pharmazie; 2009 Jul; 64(7):450-4. PubMed ID: 19694182
[TBL] [Abstract][Full Text] [Related]
10. Design and synthesis of an aminopiperidine series of γ-secretase modulators.
Kobayashi T; Iwama S; Fusano A; Kato Y; Ikeda A; Teranishi Y; Nishihara A; Tobe M
Bioorg Med Chem Lett; 2014 Jan; 24(1):378-81. PubMed ID: 24269163
[TBL] [Abstract][Full Text] [Related]
11. TASTPM mice expressing amyloid precursor protein and presenilin-1 mutant transgenes are sensitive to γ-secretase modulation and amyloid-β₄₂ lowering by GSM-10h.
Hussain I; Harrison DC; Hawkins J; Chapman T; Marshall I; Facci L; Ahmed S; Brackenborough K; Skaper SD; Mead TL; Smith BB; Giblin GM; Hall A; Gonzalez MI; Richardson JC
Neurodegener Dis; 2011; 8(1-2):15-24. PubMed ID: 20689247
[TBL] [Abstract][Full Text] [Related]
12. Autosomal-dominant Alzheimer's disease mutations at the same codon of amyloid precursor protein differentially alter Aβ production.
Suárez-Calvet M; Belbin O; Pera M; Badiola N; Magrané J; Guardia-Laguarta C; Muñoz L; Colom-Cadena M; Clarimón J; Lleó A
J Neurochem; 2014 Jan; 128(2):330-9. PubMed ID: 24117942
[TBL] [Abstract][Full Text] [Related]
13. Retrograde transport of γ-secretase from endosomes to the trans-Golgi network regulates Aβ42 production.
Kanatsu K; Hori Y; Ebinuma I; Chiu YW; Tomita T
J Neurochem; 2018 Oct; 147(1):110-123. PubMed ID: 29851073
[TBL] [Abstract][Full Text] [Related]
14. Begacestat (GSI-953): a novel, selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase for the treatment of Alzheimer's disease.
Martone RL; Zhou H; Atchison K; Comery T; Xu JZ; Huang X; Gong X; Jin M; Kreft A; Harrison B; Mayer SC; Aschmies S; Gonzales C; Zaleska MM; Riddell DR; Wagner E; Lu P; Sun SC; Sonnenberg-Reines J; Oganesian A; Adkins K; Leach MW; Clarke DW; Huryn D; Abou-Gharbia M; Magolda R; Bard J; Frick G; Raje S; Forlow SB; Balliet C; Burczynski ME; Reinhart PH; Wan HI; Pangalos MN; Jacobsen JS
J Pharmacol Exp Ther; 2009 Nov; 331(2):598-608. PubMed ID: 19671883
[TBL] [Abstract][Full Text] [Related]
15. Combining an amyloid-beta (Aβ) cleaving enzyme inhibitor with a γ-secretase modulator results in an additive reduction of Aβ production.
Strömberg K; Eketjäll S; Georgievska B; Tunblad K; Eliason K; Olsson F; Radesäter AC; Klintenberg R; Arvidsson PI; von Berg S; Fälting J; Cowburn RF; Dabrowski M
FEBS J; 2015 Jan; 282(1):65-73. PubMed ID: 25303711
[TBL] [Abstract][Full Text] [Related]
16. Specific Triazine Herbicides Induce Amyloid-β42 Production.
Portelius E; Durieu E; Bodin M; Cam M; Pannee J; Leuxe C; Mabondzo A; Oumata N; Galons H; Lee JY; Chang YT; Stϋber K; Koch P; Fontaine G; Potier MC; Manousopoulou A; Garbis SD; Covaci A; Van Dam D; De Deyn P; Karg F; Flajolet M; Omori C; Hata S; Suzuki T; Blennow K; Zetterberg H; Meijer L
J Alzheimers Dis; 2016 Oct; 54(4):1593-1605. PubMed ID: 27589520
[TBL] [Abstract][Full Text] [Related]
17. Down-regulation amyloid beta-protein 42 production by interfering with transcript of presenilin 1 gene with siRNA.
Luo HM; Deng H; Xiao F; Gao Q; Weng W; Zhang PF; Li XG
Acta Pharmacol Sin; 2004 Dec; 25(12):1613-8. PubMed ID: 15569405
[TBL] [Abstract][Full Text] [Related]
18. [Quchiling water extract inhibits secretion of beta-amyloid protein by M146L cell].
Xiao F; Luo H; Yu R; Li X; Gao Q; Zhang P; Weng W
Zhong Yao Cai; 2005 Jun; 28(6):497-9. PubMed ID: 16209268
[TBL] [Abstract][Full Text] [Related]
19. Lactacystin decreases amyloid-beta peptide production by inhibiting beta-secretase activity.
Kienlen-Campard P; Feyt C; Huysseune S; de Diesbach P; N'Kuli F; Courtoy PJ; Octave JN
J Neurosci Res; 2006 Nov; 84(6):1311-22. PubMed ID: 16941495
[TBL] [Abstract][Full Text] [Related]
20. Pharmacological characterization of the novel γ-secretase modulator AS2715348, a potential therapy for Alzheimer's disease, in rodents and nonhuman primates.
Mitani Y; Akashiba H; Saita K; Yarimizu J; Uchino H; Okabe M; Asai M; Yamasaki S; Nozawa T; Ishikawa N; Shitaka Y; Ni K; Matsuoka N
Neuropharmacology; 2014 Apr; 79():412-9. PubMed ID: 24373902
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]