BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 17296554)

  • 1. Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity.
    Ihara M; Yamasaki N; Hagiwara A; Tanigaki A; Kitano A; Hikawa R; Tomimoto H; Noda M; Takanashi M; Mori H; Hattori N; Miyakawa T; Kinoshita M
    Neuron; 2007 Feb; 53(4):519-33. PubMed ID: 17296554
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Expression of Lewy body protein septin 4 in postmortem brain of Parkinson's disease and control subjects.
    Shehadeh L; Mitsi G; Adi N; Bishopric N; Papapetropoulos S
    Mov Disord; 2009 Jan; 24(2):204-10. PubMed ID: 18951507
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chronic overload of SEPT4, a parkin substrate that aggregates in Parkinson's disease, causes behavioral alterations but not neurodegeneration in mice.
    Ageta-Ishihara N; Yamakado H; Morita T; Hattori S; Takao K; Miyakawa T; Takahashi R; Kinoshita M
    Mol Brain; 2013 Aug; 6():35. PubMed ID: 23938054
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Association of the cytoskeletal GTP-binding protein Sept4/H5 with cytoplasmic inclusions found in Parkinson's disease and other synucleinopathies.
    Ihara M; Tomimoto H; Kitayama H; Morioka Y; Akiguchi I; Shibasaki H; Noda M; Kinoshita M
    J Biol Chem; 2003 Jun; 278(26):24095-102. PubMed ID: 12695511
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Authentically phosphorylated α-synuclein at Ser129 accelerates neurodegeneration in a rat model of familial Parkinson's disease.
    Sato H; Arawaka S; Hara S; Fukushima S; Koga K; Koyama S; Kato T
    J Neurosci; 2011 Nov; 31(46):16884-94. PubMed ID: 22090514
    [TBL] [Abstract][Full Text] [Related]  

  • 6. AAV1/2-induced overexpression of A53T-α-synuclein in the substantia nigra results in degeneration of the nigrostriatal system with Lewy-like pathology and motor impairment: a new mouse model for Parkinson's disease.
    Ip CW; Klaus LC; Karikari AA; Visanji NP; Brotchie JM; Lang AE; Volkmann J; Koprich JB
    Acta Neuropathol Commun; 2017 Feb; 5(1):11. PubMed ID: 28143577
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Climbing the scaffolds of Parkinson's disease pathogenesis.
    Spencer B; Crews L; Masliah E
    Neuron; 2007 Feb; 53(4):469-70. PubMed ID: 17296545
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease.
    Chen L; Feany MB
    Nat Neurosci; 2005 May; 8(5):657-63. PubMed ID: 15834418
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Proteinase K-resistant alpha-synuclein is deposited in presynapses in human Lewy body disease and A53T alpha-synuclein transgenic mice.
    Tanji K; Mori F; Mimura J; Itoh K; Kakita A; Takahashi H; Wakabayashi K
    Acta Neuropathol; 2010 Aug; 120(2):145-54. PubMed ID: 20339856
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synphilin-1-binding protein NUB1 is colocalized with nonfibrillar, proteinase K-resistant α-synuclein in presynapses in Lewy body disease.
    Tanji K; Mori F; Kito K; Kakita A; Mimura J; Itoh K; Takahashi H; Kamitani T; Wakabayashi K
    J Neuropathol Exp Neurol; 2011 Oct; 70(10):879-89. PubMed ID: 21937912
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Down syndrome candidate dual-specificity tyrosine phosphorylation-regulated kinase 1A phosphorylates the neurodegeneration-related septin 4.
    Sitz JH; Baumgärtel K; Hämmerle B; Papadopoulos C; Hekerman P; Tejedor FJ; Becker W; Lutz B
    Neuroscience; 2008 Dec; 157(3):596-605. PubMed ID: 18938227
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nuclear and neuritic distribution of serine-129 phosphorylated alpha-synuclein in transgenic mice.
    Schell H; Hasegawa T; Neumann M; Kahle PJ
    Neuroscience; 2009 Jun; 160(4):796-804. PubMed ID: 19272424
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Early synaptic dysfunction induced by α-synuclein in a rat model of Parkinson's disease.
    Phan JA; Stokholm K; Zareba-Paslawska J; Jakobsen S; Vang K; Gjedde A; Landau AM; Romero-Ramos M
    Sci Rep; 2017 Jul; 7(1):6363. PubMed ID: 28743955
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanisms underlying extensive Ser129-phosphorylation in α-synuclein aggregates.
    Arawaka S; Sato H; Sasaki A; Koyama S; Kato T
    Acta Neuropathol Commun; 2017 Jun; 5(1):48. PubMed ID: 28619113
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MicroRNA expressing profiles in A53T mutant alpha-synuclein transgenic mice and Parkinsonian.
    Mo M; Xiao Y; Huang S; Cen L; Chen X; Zhang L; Luo Q; Li S; Yang X; Lin X; Xu P
    Oncotarget; 2017 Jan; 8(1):15-28. PubMed ID: 27965467
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Age-dependent effects of A53T alpha-synuclein on behavior and dopaminergic function.
    Oaks AW; Frankfurt M; Finkelstein DI; Sidhu A
    PLoS One; 2013; 8(4):e60378. PubMed ID: 23560093
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dopamine transporter-mediated cytotoxicity of 6-hydroxydopamine in vitro depends on expression of mutant alpha-synucleins related to Parkinson's disease.
    Lehmensiek V; Tan EM; Liebau S; Lenk T; Zettlmeisl H; Schwarz J; Storch A
    Neurochem Int; 2006 Apr; 48(5):329-40. PubMed ID: 16406146
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Extracellular α-synuclein enters dopaminergic cells by modulating flotillin-1-assisted dopamine transporter endocytosis.
    Kobayashi J; Hasegawa T; Sugeno N; Yoshida S; Akiyama T; Fujimori K; Hatakeyama H; Miki Y; Tomiyama A; Kawata Y; Fukuda M; Kawahata I; Yamakuni T; Ezura M; Kikuchi A; Baba T; Takeda A; Kanzaki M; Wakabayashi K; Okano H; Aoki M
    FASEB J; 2019 Sep; 33(9):10240-10256. PubMed ID: 31211923
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The role of Ser129 phosphorylation of α-synuclein in neurodegeneration of Parkinson's disease: a review of in vivo models.
    Sato H; Kato T; Arawaka S
    Rev Neurosci; 2013; 24(2):115-23. PubMed ID: 23314528
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Locomotor hyperactivity and alterations in dopamine neurotransmission are associated with overexpression of A53T mutant human alpha-synuclein in mice.
    Unger EL; Eve DJ; Perez XA; Reichenbach DK; Xu Y; Lee MK; Andrews AM
    Neurobiol Dis; 2006 Feb; 21(2):431-43. PubMed ID: 16230020
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.