These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

123 related articles for article (PubMed ID: 17298046)

  • 1. Synthesis and preliminary evaluation of 18F- or 11C-labeled bicyclic nucleoside analogues as potential probes for imaging varicella-zoster virus thymidine kinase gene expression using positron emission tomography.
    Chitneni SK; Deroose CM; Balzarini J; Gijsbers R; Celen SJ; de Groot TJ; Debyser Z; Mortelmans L; Verbruggen AM; Bormans GM
    J Med Chem; 2007 Mar; 50(5):1041-9. PubMed ID: 17298046
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A p-[18F]fluoroethoxyphenyl bicyclic nucleoside analogue as a potential positron emission tomography imaging agent for varicella-zoster virus thymidine kinase gene expression.
    Chitneni SK; Deroose CM; Balzarini J; Gijsbers R; Celen S; Debyser Z; Mortelmans L; Verbruggen AM; Bormans GM
    J Med Chem; 2007 Dec; 50(26):6627-37. PubMed ID: 18047266
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Preliminary validation of varicella zoster virus thymidine kinase as a novel reporter gene for PET.
    Deroose CM; Chitneni SK; Gijsbers R; Vermaelen P; Ibrahimi A; Balzarini J; Baekelandt V; Verbruggen A; Nuyts J; Debyser Z; Bormans GM; Mortelmans L
    Nucl Med Biol; 2012 Nov; 39(8):1266-74. PubMed ID: 22981986
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and biological evaluation of an 123I-labeled bicyclic nucleoside analogue (BCNA) as potential SPECT tracer for VZV-tk reporter gene imaging.
    Chitneni SK; Deroose CM; Fonge H; Gijsbers R; Dyubankova N; Balzarini J; Debyser Z; Mortelmans L; Verbruggen AM; Bormans GM
    Bioorg Med Chem Lett; 2007 Jun; 17(12):3458-62. PubMed ID: 17446073
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and evaluation of [18F] labeled pyrimidine nucleosides for positron emission tomography imaging of herpes simplex virus 1 thymidine kinase gene expression.
    Pillarsetty N; Cai S; Ageyeva L; Finn RD; Blasberg RG
    J Med Chem; 2006 Aug; 49(17):5377-81. PubMed ID: 16913728
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 5-[18F]Fluoroalkyl pyrimidine nucleosides: probes for positron emission tomography imaging of herpes simplex virus type 1 thymidine kinase gene expression.
    Chacko AM; Blankemeyer E; Lieberman BP; Qu W; Kung HF
    Nucl Med Biol; 2009 Jan; 36(1):29-38. PubMed ID: 19181266
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bicyclic pyrimidine nucleoside analogues (BCNAs) as highly selective and potent inhibitors of varicella-zoster virus replication.
    Balzarini J; McGuigan C
    J Antimicrob Chemother; 2002 Jul; 50(1):5-9. PubMed ID: 12096000
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Imaging of HSV-tk Reporter gene expression: comparison between [18F]FEAU, [18F]FFEAU, and other imaging probes.
    Miyagawa T; Gogiberidze G; Serganova I; Cai S; Balatoni JA; Thaler HT; Ageyeva L; Pillarsetty N; Finn RD; Blasberg RG
    J Nucl Med; 2008 Apr; 49(4):637-48. PubMed ID: 18344433
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lack of susceptibility of bicyclic nucleoside analogs, highly potent inhibitors of varicella-zoster virus, to the catabolic action of thymidine phosphorylase and dihydropyrimidine dehydrogenase.
    Balzarini J; Sienaert R; Liekens S; Van Kuilenburg A; Carangio A; Esnouf R; De Clercq E; McGuigan C
    Mol Pharmacol; 2002 May; 61(5):1140-5. PubMed ID: 11961132
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutations distal to the substrate site can affect varicella zoster virus thymidine kinase activity: implications for drug design.
    El Omari K; Liekens S; Bird LE; Balzarini J; Stammers DK
    Mol Pharmacol; 2006 Jun; 69(6):1891-6. PubMed ID: 16556772
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and evaluation of 2'-deoxy-2'-18F-fluoro-5-fluoro-1-beta-D-arabinofuranosyluracil as a potential PET imaging agent for suicide gene expression.
    Alauddin MM; Shahinian A; Park R; Tohme M; Fissekis JD; Conti PS
    J Nucl Med; 2004 Dec; 45(12):2063-9. PubMed ID: 15585483
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inactivity of the bicyclic pyrimidine nucleoside analogues against simian varicella virus (SVV) does not correlate with their substrate activity for SVV-encoded thymidine kinase.
    Sienaert R; Andrei G; Snoeck R; De Clercq E; McGuigan C; Balzarini J
    Biochem Biophys Res Commun; 2004 Mar; 315(4):877-83. PubMed ID: 14985094
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Preparation and biological evaluation of 2-amino-6-[18F]fluoro-9-(4-hydroxy-3-hydroxy-methylbutyl) purine (6-[18F]FPCV) as a novel PET probe for imaging HSV1-tk reporter gene expression.
    Cai H; Yin D; Zhang L; Yang X; Xu X; Liu W; Zheng X; Zhang H; Wang J; Xu Y; Cheng D; Zheng M; Han Y; Wu M; Wang Y
    Nucl Med Biol; 2007 Aug; 34(6):717-25. PubMed ID: 17707813
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Varicella-zoster virus thymidine kinase gene and antiherpetic pyrimidine nucleoside analogues in a combined gene/chemotherapy treatment for cancer.
    Degrève B; Andrei G; Izquierdo M; Piette J; Morin K; Knaus EE; Wiebe LI; Basrah I; Walker RT; De Clercq E; Balzarini J
    Gene Ther; 1997 Oct; 4(10):1107-14. PubMed ID: 9415318
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evaluation of novel phosphoramidate ProTides of the 2'-fluoro derivatives of a potent anti-varicella zoster virus bicyclic nucleoside analogue.
    Derudas M; Quintiliani M; Brancale A; Andrei G; Snoeck R; Balzarini J; McGuigan C
    Antivir Chem Chemother; 2010 Oct; 21(1):15-31. PubMed ID: 21045257
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular-genetic PET imaging using an HSV1-tk mutant reporter gene with enhanced specificity to acycloguanosine nucleoside analogs.
    Najjar AM; Nishii R; Maxwell DS; Volgin A; Mukhopadhyay U; Bornmann WG; Tong W; Alauddin M; Gelovani JG
    J Nucl Med; 2009 Mar; 50(3):409-16. PubMed ID: 19223410
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Quantitative kinetics of [124I]FIAU in cat and man.
    Jacobs A; Bräunlich I; Graf R; Lercher M; Sakaki T; Voges J; Hesselmann V; Brandau W; Wienhard K; Heiss WD
    J Nucl Med; 2001 Mar; 42(3):467-75. PubMed ID: 11337525
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of 1-(2-deoxy-beta-D-ribofuranosyl)-2,4-difluoro-5-substituted-benzenes: "thymine replacement" analogs of thymidine for evaluation as anticancer and antiviral agents.
    Wang ZX; Duan W; Wiebe LI; Balzarini J; De Clercq E; Knaus EE
    Nucleosides Nucleotides Nucleic Acids; 2001; 20(1-2):41-58. PubMed ID: 11303562
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparison of radiolabeled nucleoside probes (FIAU, FHBG, and FHPG) for PET imaging of HSV1-tk gene expression.
    Tjuvajev JG; Doubrovin M; Akhurst T; Cai S; Balatoni J; Alauddin MM; Finn R; Bornmann W; Thaler H; Conti PS; Blasberg RG
    J Nucl Med; 2002 Aug; 43(8):1072-83. PubMed ID: 12163634
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Highly potent and selective inhibition of varicella-zoster virus replication by bicyclic furo[2,3-d]pyrimidine nucleoside analogues.
    De Clercq E
    Med Res Rev; 2003 May; 23(3):253-74. PubMed ID: 12647310
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.