BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 17298440)

  • 1. The propeptide of cruzipain--a potent selective inhibitor of the trypanosomal enzymes cruzipain and brucipain, and of the human enzyme cathepsin F.
    Reis FC; Costa TF; Sulea T; Mezzetti A; Scharfstein J; Brömme D; Ménard R; Lima AP
    FEBS J; 2007 Mar; 274(5):1224-34. PubMed ID: 17298440
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Potency and selectivity of the cathepsin L propeptide as an inhibitor of cysteine proteases.
    Carmona E; Dufour E; Plouffe C; Takebe S; Mason P; Mort JS; Ménard R
    Biochemistry; 1996 Jun; 35(25):8149-57. PubMed ID: 8679567
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structure of human procathepsin X: a cysteine protease with the proregion covalently linked to the active site cysteine.
    Sivaraman J; Nägler DK; Zhang R; Ménard R; Cygler M
    J Mol Biol; 2000 Jan; 295(4):939-51. PubMed ID: 10656802
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Full-length cDNA of human cathepsin F predicts the presence of a cystatin domain at the N-terminus of the cysteine protease zymogen.
    Nägler DK; Sulea T; Ménard R
    Biochem Biophys Res Commun; 1999 Apr; 257(2):313-8. PubMed ID: 10198209
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Potency and selectivity of inhibition of cathepsin K, L and S by their respective propeptides.
    Guay J; Falgueyret JP; Ducret A; Percival MD; Mancini JA
    Eur J Biochem; 2000 Oct; 267(20):6311-8. PubMed ID: 11012686
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Biotin-labelled peptidyl diazomethane inhibitors derived from the substrate-like sequence of cystatin: targeting of the active site of cruzipain, the major cysteine proteinase of Trypanosoma cruzi.
    Lalmanach G; Mayer R; Serveau C; Scharfstein J; Gauthier F
    Biochem J; 1996 Sep; 318 ( Pt 2)(Pt 2):395-9. PubMed ID: 8809025
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The occluding loop in cathepsin B defines the pH dependence of inhibition by its propeptide.
    Quraishi O; Nägler DK; Fox T; Sivaraman J; Cygler M; Mort JS; Storer AC
    Biochemistry; 1999 Apr; 38(16):5017-23. PubMed ID: 10213604
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The crystal structure of human procathepsin K.
    LaLonde JM; Zhao B; Janson CA; D'Alessio KJ; McQueney MS; Orsini MJ; Debouck CM; Smith WW
    Biochemistry; 1999 Jan; 38(3):862-9. PubMed ID: 9893980
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New peptidic cysteine protease inhibitors derived from the electrophilic alpha-amino acid aziridine-2,3-dicarboxylic acid.
    Schirmeister T
    J Med Chem; 1999 Feb; 42(4):560-72. PubMed ID: 10052963
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Production and characterization of two variants of human cystatin SA encoded by two alleles at the CST2 locus of the type 2 cystatin gene family.
    Saitoh E; Minaguchi K; Ishibashi O
    Arch Biochem Biophys; 1998 Apr; 352(2):199-206. PubMed ID: 9587407
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discrimination of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, and mammalian cathepsins B and L, by a pH-inducible fluorogenic substrate of trypanosomal cysteine proteinases.
    Serveau C; Lalmanach G; Hirata I; Scharfstein J; Juliano MA; Gauthier F
    Eur J Biochem; 1999 Jan; 259(1-2):275-80. PubMed ID: 9914503
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cysteine protease isoforms from Trypanosoma cruzi, cruzipain 2 and cruzain, present different substrate preference and susceptibility to inhibitors.
    Lima AP; dos Reis FC; Serveau C; Lalmanach G; Juliano L; Ménard R; Vernet T; Thomas DY; Storer AC; Scharfstein J
    Mol Biochem Parasitol; 2001 Apr; 114(1):41-52. PubMed ID: 11356512
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Importance of the second binding loop and the C-terminal end of cystatin B (stefin B) for inhibition of cysteine proteinases.
    Pol E; Björk I
    Biochemistry; 1999 Aug; 38(32):10519-26. PubMed ID: 10441148
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural basis for specificity of papain-like cysteine protease proregions toward their cognate enzymes.
    Groves MR; Coulombe R; Jenkins J; Cygler M
    Proteins; 1998 Sep; 32(4):504-14. PubMed ID: 9726419
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential effect toward inhibition of papain and cathepsin C by recombinant human salivary cystatin SN and its variants produced by a baculovirus system.
    Tseng CC; Tseng CP; Levine MJ; Bobek LA
    Arch Biochem Biophys; 2000 Aug; 380(1):133-40. PubMed ID: 10900142
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Investigation of the substrate specificity of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, through the use of cystatin-derived substrates and inhibitors.
    Serveau C; Lalmanach G; Juliano MA; Scharfstein J; Juliano L; Gauthier F
    Biochem J; 1996 Feb; 313 ( Pt 3)(Pt 3):951-6. PubMed ID: 8611180
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bombyx cysteine proteinase inhibitor (BCPI) homologous to propeptide regions of cysteine proteinases is a strong, selective inhibitor of cathepsin L-like cysteine proteinases.
    Kurata M; Yamamoto Y; Watabe S; Makino Y; Ogawa K; Takahashi SY
    J Biochem; 2001 Dec; 130(6):857-63. PubMed ID: 11726287
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The propeptide of Fasciola hepatica cathepsin L is a potent and selective inhibitor of the mature enzyme.
    Roche L; Tort J; Dalton JP
    Mol Biochem Parasitol; 1999 Jan; 98(2):271-7. PubMed ID: 10080395
    [No Abstract]   [Full Text] [Related]  

  • 19. The slow-binding inhibition of cathepsin K by its propeptide.
    Billington CJ; Mason P; Magny MC; Mort JS
    Biochem Biophys Res Commun; 2000 Oct; 276(3):924-9. PubMed ID: 11027570
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structure of the wild-type human procathepsin B at 2.5 A resolution reveals the native active site of a papain-like cysteine protease zymogen.
    Podobnik M; Kuhelj R; Turk V; Turk D
    J Mol Biol; 1997 Sep; 271(5):774-88. PubMed ID: 9299326
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.