These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 1730674)

  • 21. Probing the role of parasite-specific, distant structural regions on communication and catalysis in the bifunctional thymidylate synthase-dihydrofolate reductase from Plasmodium falciparum.
    Dasgupta T; Anderson KS
    Biochemistry; 2008 Feb; 47(5):1336-45. PubMed ID: 18189414
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Human dihydrofolate reductase: reduction of alternative substrates, pH effects, and inhibition by deazafolates.
    Williams EA; Morrison JF
    Biochemistry; 1992 Jul; 31(29):6801-11. PubMed ID: 1637816
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Expression of bovine heart fructose 6-phosphate,2-kinase:fructose 2,6-bisphosphatase and determination of the role of the carboxyl terminus by mutagenesis.
    Abe Y; Minami Y; Li Y; Nguyen C; Uyeda K
    Biochemistry; 1995 Feb; 34(8):2553-9. PubMed ID: 7873535
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Probing the role of two hydrophobic active site residues in the human dihydrofolate reductase by site-directed mutagenesis.
    Schweitzer BI; Srimatkandada S; Gritsman H; Sheridan R; Venkataraghavan R; Bertino JR
    J Biol Chem; 1989 Dec; 264(34):20786-95. PubMed ID: 2684985
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Conformation coupled enzyme catalysis: single-molecule and transient kinetics investigation of dihydrofolate reductase.
    Antikainen NM; Smiley RD; Benkovic SJ; Hammes GG
    Biochemistry; 2005 Dec; 44(51):16835-43. PubMed ID: 16363797
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Coupling interactions of distal residues enhance dihydrofolate reductase catalysis: mutational effects on hydride transfer rates.
    Rajagopalan PT; Lutz S; Benkovic SJ
    Biochemistry; 2002 Oct; 41(42):12618-28. PubMed ID: 12379104
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Purification and properties of dihydrofolate reductase from cultured mammalian cells.
    Gauldie J; Marshall L; Hillcoat BL
    Biochem J; 1973 Jun; 133(2):349-56. PubMed ID: 4723779
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Disruption of the crossover helix impairs dihydrofolate reductase activity in the bifunctional enzyme TS-DHFR from Cryptosporidium hominis.
    Vargo MA; Martucci WE; Anderson KS
    Biochem J; 2009 Feb; 417(3):757-64. PubMed ID: 18851711
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Molecular characterization of dihydrofolate reductase in relation to antifolate resistance in Plasmodium vivax.
    Leartsakulpanich U; Imwong M; Pukrittayakamee S; White NJ; Snounou G; Sirawaraporn W; Yuthavong Y
    Mol Biochem Parasitol; 2002 Jan; 119(1):63-73. PubMed ID: 11755187
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Kinetic characterization of dihydrofolate reductase from Drosophila melanogaster.
    Rancourt SL; Walker VK
    Biochem Cell Biol; 1990 Sep; 68(9):1075-82. PubMed ID: 2124130
    [TBL] [Abstract][Full Text] [Related]  

  • 31. A 19-base pair deletion polymorphism in dihydrofolate reductase is associated with increased unmetabolized folic acid in plasma and decreased red blood cell folate.
    Kalmbach RD; Choumenkovitch SF; Troen AP; Jacques PF; D'Agostino R; Selhub J
    J Nutr; 2008 Dec; 138(12):2323-7. PubMed ID: 19022952
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Effects of point mutations in a hinge region on the stability, folding, and enzymatic activity of Escherichia coli dihydrofolate reductase.
    Ahrweiler PM; Frieden C
    Biochemistry; 1991 Aug; 30(31):7801-9. PubMed ID: 1868058
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Role of lysine-54 in determining cofactor specificity and binding in human dihydrofolate reductase.
    Huang S; Appleman R; Tan XH; Thompson PD; Blakley RL; Sheridan RP; Venkataraghavan R; Freisheim JH
    Biochemistry; 1990 Sep; 29(35):8063-9. PubMed ID: 2124504
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Invariant amino acid replacement affects the dihydrofolate reductase function and its gene expression.
    Murzina NV; Gudkov AT
    Protein Eng; 1990 Aug; 3(8):709-12. PubMed ID: 2217143
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Conformational change of dihydrofolate reductase near the active site after thiol modification: detected by limited proteolysis.
    Li ZY; Zhou JM
    Biochim Biophys Acta; 2000 Aug; 1481(1):37-44. PubMed ID: 10962090
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Coupling effects of distal loops on structural stability and enzymatic activity of Escherichia coli dihydrofolate reductase revealed by deletion mutants.
    Horiuchi Y; Ohmae E; Tate S; Gekko K
    Biochim Biophys Acta; 2010 Apr; 1804(4):846-55. PubMed ID: 20045086
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A fully active variant of dihydrofolate reductase with a circularly permuted sequence.
    Buchwalder A; Szadkowski H; Kirschner K
    Biochemistry; 1992 Feb; 31(6):1621-30. PubMed ID: 1737018
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Effects of conversion of phenylalanine-31 to leucine on the function of human dihydrofolate reductase.
    Prendergast NJ; Appleman JR; Delcamp TJ; Blakley RL; Freisheim JH
    Biochemistry; 1989 May; 28(11):4645-50. PubMed ID: 2765506
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Dihydrofolate reductase from Kaposi's sarcoma-associated herpesvirus.
    Cinquina CC; Grogan E; Sun R; Lin SF; Beardsley GP; Miller G
    Virology; 2000 Mar; 268(1):201-17. PubMed ID: 10683342
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The tail wagging the dog: insights into catalysis in R67 dihydrofolate reductase.
    Kamath G; Howell EE; Agarwal PK
    Biochemistry; 2010 Oct; 49(42):9078-88. PubMed ID: 20795731
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.