BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

494 related articles for article (PubMed ID: 17308097)

  • 1. A Src/Abl kinase inhibitor, SKI-606, blocks breast cancer invasion, growth, and metastasis in vitro and in vivo.
    Jallal H; Valentino ML; Chen G; Boschelli F; Ali S; Rabbani SA
    Cancer Res; 2007 Feb; 67(4):1580-8. PubMed ID: 17308097
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SKI-606 decreases growth and motility of colorectal cancer cells by preventing pp60(c-Src)-dependent tyrosine phosphorylation of beta-catenin and its nuclear signaling.
    Coluccia AM; Benati D; Dekhil H; De Filippo A; Lan C; Gambacorti-Passerini C
    Cancer Res; 2006 Feb; 66(4):2279-86. PubMed ID: 16489032
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SKI-606, a 4-anilino-3-quinolinecarbonitrile dual inhibitor of Src and Abl kinases, is a potent antiproliferative agent against chronic myelogenous leukemia cells in culture and causes regression of K562 xenografts in nude mice.
    Golas JM; Arndt K; Etienne C; Lucas J; Nardin D; Gibbons J; Frost P; Ye F; Boschelli DH; Boschelli F
    Cancer Res; 2003 Jan; 63(2):375-81. PubMed ID: 12543790
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SKI-606, a Src/Abl inhibitor with in vivo activity in colon tumor xenograft models.
    Golas JM; Lucas J; Etienne C; Golas J; Discafani C; Sridharan L; Boghaert E; Arndt K; Ye F; Boschelli DH; Li F; Titsch C; Huselton C; Chaudhary I; Boschelli F
    Cancer Res; 2005 Jun; 65(12):5358-64. PubMed ID: 15958584
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PH006, a novel and selective Src kinase inhibitor, suppresses human breast cancer growth and metastasis in vitro and in vivo.
    Ma JG; Huang H; Chen SM; Chen Y; Xin XL; Lin LP; Ding J; Liu H; Meng LH
    Breast Cancer Res Treat; 2011 Nov; 130(1):85-96. PubMed ID: 21181437
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Upregulation and activation of PKC alpha by ErbB2 through Src promotes breast cancer cell invasion that can be blocked by combined treatment with PKC alpha and Src inhibitors.
    Tan M; Li P; Sun M; Yin G; Yu D
    Oncogene; 2006 Jun; 25(23):3286-95. PubMed ID: 16407820
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of non-receptor and receptor tyrosine kinases (TKs) in the antitumor action of alpha-difluoromethylornithine (DFMO) in breast cancer cells.
    Xu H; Washington S; Verderame MF; Manni A
    Breast Cancer Res Treat; 2008 Nov; 112(2):255-61. PubMed ID: 18097746
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Denbinobin suppresses breast cancer metastasis through the inhibition of Src-mediated signaling pathways.
    Chen PH; Peng CY; Pai HC; Teng CM; Chen CC; Yang CR
    J Nutr Biochem; 2011 Aug; 22(8):732-40. PubMed ID: 21062671
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Apigenin inhibits HGF-promoted invasive growth and metastasis involving blocking PI3K/Akt pathway and beta 4 integrin function in MDA-MB-231 breast cancer cells.
    Lee WJ; Chen WK; Wang CJ; Lin WL; Tseng TH
    Toxicol Appl Pharmacol; 2008 Jan; 226(2):178-91. PubMed ID: 17961621
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Persistent Cdk2 inactivation drives growth arrest of BCR-ABL-expressing cells in response to dual inhibitor of SRC and ABL kinases SKI606.
    Mancini M; Brusa G; Zuffa E; Corrado P; Martinelli G; Grafone T; Barbieri E; Santucci MA
    Leuk Res; 2007 Jul; 31(7):979-87. PubMed ID: 17129604
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Silencing of transforming growth factor-beta1 in situ by RNA interference for breast cancer: implications for proliferation and migration in vitro and metastasis in vivo.
    Moore LD; Isayeva T; Siegal GP; Ponnazhagan S
    Clin Cancer Res; 2008 Aug; 14(15):4961-70. PubMed ID: 18676771
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ki26894, a novel transforming growth factor-beta type I receptor kinase inhibitor, inhibits in vitro invasion and in vivo bone metastasis of a human breast cancer cell line.
    Ehata S; Hanyu A; Fujime M; Katsuno Y; Fukunaga E; Goto K; Ishikawa Y; Nomura K; Yokoo H; Shimizu T; Ogata E; Miyazono K; Shimizu K; Imamura T
    Cancer Sci; 2007 Jan; 98(1):127-33. PubMed ID: 17129361
    [TBL] [Abstract][Full Text] [Related]  

  • 13. TrkA overexpression enhances growth and metastasis of breast cancer cells.
    Lagadec C; Meignan S; Adriaenssens E; Foveau B; Vanhecke E; Romon R; Toillon RA; Oxombre B; Hondermarck H; Le Bourhis X
    Oncogene; 2009 May; 28(18):1960-70. PubMed ID: 19330021
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of Smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells.
    Azuma H; Ehata S; Miyazaki H; Watabe T; Maruyama O; Imamura T; Sakamoto T; Kiyama S; Kiyama Y; Ubai T; Inamoto T; Takahara S; Itoh Y; Otsuki Y; Katsuoka Y; Miyazono K; Horie S
    J Natl Cancer Inst; 2005 Dec; 97(23):1734-46. PubMed ID: 16333029
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Signal therapy of human pancreatic cancer and NF1-deficient breast cancer xenograft in mice by a combination of PP1 and GL-2003, anti-PAK1 drugs (Tyr-kinase inhibitors).
    Hirokawa Y; Levitzki A; Lessene G; Baell J; Xiao Y; Zhu H; Maruta H
    Cancer Lett; 2007 Jan; 245(1-2):242-51. PubMed ID: 16540233
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of rho-associated kinase signaling prevents breast cancer metastasis to human bone.
    Liu S; Goldstein RH; Scepansky EM; Rosenblatt M
    Cancer Res; 2009 Nov; 69(22):8742-51. PubMed ID: 19887617
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of tumor cell growth, invasion, and metastasis by EXEL-2880 (XL880, GSK1363089), a novel inhibitor of HGF and VEGF receptor tyrosine kinases.
    Qian F; Engst S; Yamaguchi K; Yu P; Won KA; Mock L; Lou T; Tan J; Li C; Tam D; Lougheed J; Yakes FM; Bentzien F; Xu W; Zaks T; Wooster R; Greshock J; Joly AH
    Cancer Res; 2009 Oct; 69(20):8009-16. PubMed ID: 19808973
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effect of Src kinase inhibition on metastasis and tumor angiogenesis in human pancreatic cancer.
    Ischenko I; Guba M; Yezhelyev M; Papyan A; Schmid G; Green T; Fennell M; Jauch KW; Bruns CJ
    Angiogenesis; 2007; 10(3):167-82. PubMed ID: 17486419
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Suppression of distant pulmonary metastasis of MDA-MB 435 human breast carcinoma established in mammary fat pads of nude mice by retroviral-mediated TIMP-2 gene transfer.
    Lee YK; So IS; Lee SC; Lee JH; Lee CW; Kim WM; Park MK; Lee ST; Park DY; Shin DY; Park CU; Kim YS
    J Gene Med; 2005 Feb; 7(2):145-57. PubMed ID: 15546163
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SKI-606 (bosutinib), a novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells.
    Vultur A; Buettner R; Kowolik C; Liang W; Smith D; Boschelli F; Jove R
    Mol Cancer Ther; 2008 May; 7(5):1185-94. PubMed ID: 18483306
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.