These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 17311914)

  • 1. Crystal structure of the T877A human androgen receptor ligand-binding domain complexed to cyproterone acetate provides insight for ligand-induced conformational changes and structure-based drug design.
    Bohl CE; Wu Z; Miller DD; Bell CE; Dalton JT
    J Biol Chem; 2007 May; 282(18):13648-55. PubMed ID: 17311914
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The androgen receptor T877A mutant recruits LXXLL and FXXLF peptides differently than wild-type androgen receptor in a time-resolved fluorescence resonance energy transfer assay.
    Ozers MS; Marks BD; Gowda K; Kupcho KR; Ervin KM; De Rosier T; Qadir N; Eliason HC; Riddle SM; Shekhani MS
    Biochemistry; 2007 Jan; 46(3):683-95. PubMed ID: 17223690
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone.
    Sack JS; Kish KF; Wang C; Attar RM; Kiefer SE; An Y; Wu GY; Scheffler JE; Salvati ME; Krystek SR; Weinmann R; Einspahr HM
    Proc Natl Acad Sci U S A; 2001 Apr; 98(9):4904-9. PubMed ID: 11320241
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutation of the androgen receptor at amino acid 708 (Gly-->Ala) abolishes partial agonist activity of steroidal antiandrogens.
    Terouanne B; Nirdé P; Rabenoelina F; Bourguet W; Sultan C; Auzou G
    Mol Pharmacol; 2003 Apr; 63(4):791-8. PubMed ID: 12644579
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential modulation of androgen receptor transcriptional activity by the nuclear receptor co-repressor (N-CoR).
    Berrevoets CA; Umar A; Trapman J; Brinkmann AO
    Biochem J; 2004 May; 379(Pt 3):731-8. PubMed ID: 14744261
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural basis for the glucocorticoid response in a mutant human androgen receptor (AR(ccr)) derived from an androgen-independent prostate cancer.
    Matias PM; Carrondo MA; Coelho R; Thomaz M; Zhao XY; Wegg A; Crusius K; Egner U; Donner P
    J Med Chem; 2002 Mar; 45(7):1439-46. PubMed ID: 11906285
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human androgen receptor gene ligand-binding-domain mutations leading to disrupted interaction between the N- and C-terminal domains.
    Jääskeläinen J; Deeb A; Schwabe JW; Mongan NP; Martin H; Hughes IA
    J Mol Endocrinol; 2006 Apr; 36(2):361-8. PubMed ID: 16595706
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural features discriminate androgen receptor N/C terminal and coactivator interactions.
    Askew EB; Minges JT; Hnat AT; Wilson EM
    Mol Cell Endocrinol; 2012 Jan; 348(2):403-10. PubMed ID: 21664945
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A partially open conformation of an androgen receptor ligand-binding domain with drug-resistance mutations.
    Doamekpor SK; Peng P; Xu R; Ma L; Tong Y; Tong L
    Acta Crystallogr F Struct Biol Commun; 2023 Apr; 79(Pt 4):95-104. PubMed ID: 36995121
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Study of the impact of the T877A mutation on ligand-induced helix-12 positioning of the androgen receptor resulted in design and synthesis of novel antiandrogens.
    Zhou J; Liu B; Geng G; Wu JH
    Proteins; 2010 Feb; 78(3):623-37. PubMed ID: 19787772
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Study of novel androgen receptor V770 variant in androgen insensitivity syndrome patients reveals the transitional state of the androgen receptor ligand binding domain homodimer.
    Helsen C; Rocca MS; Nguyen TT; Eerlings R; Lee XY; De Block S; Vinanzi C; Di Millo F; Giagulli V; Voet A; Ferlin A; Claessens F
    Protein Sci; 2023 Apr; 32(4):e4599. PubMed ID: 36806291
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sequences in the ligand-binding domains of the human androgen and progesterone receptors which determine their distinct ligand identities.
    Vivat V; Gofflo D; Garcia T; Wurtz JM; Bourguet W; Philibert D; Gronemeyer H
    J Mol Endocrinol; 1997 Apr; 18(2):147-60. PubMed ID: 9134501
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Learning from estrogen receptor antagonism: structure-based identification of novel antiandrogens effective against multiple clinically relevant androgen receptor mutants.
    Liu B; Geng G; Lin R; Ren C; Wu JH
    Chem Biol Drug Des; 2012 Mar; 79(3):300-12. PubMed ID: 22151347
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modulation of androgen receptor activation function 2 by testosterone and dihydrotestosterone.
    Askew EB; Gampe RT; Stanley TB; Faggart JL; Wilson EM
    J Biol Chem; 2007 Aug; 282(35):25801-16. PubMed ID: 17591767
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural basis for accommodation of nonsteroidal ligands in the androgen receptor.
    Bohl CE; Miller DD; Chen J; Bell CE; Dalton JT
    J Biol Chem; 2005 Nov; 280(45):37747-54. PubMed ID: 16129672
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evidence that chlormadinone acetate exhibits antiandrogenic activity in androgen-dependent cell line.
    Térouanne B; Paris F; Servant N; Georget V; Sultan C
    Mol Cell Endocrinol; 2002 Dec; 198(1-2):143-7. PubMed ID: 12573824
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Systematic structure-function analysis of androgen receptor Leu701 mutants explains the properties of the prostate cancer mutant L701H.
    van de Wijngaart DJ; Molier M; Lusher SJ; Hersmus R; Jenster G; Trapman J; Dubbink HJ
    J Biol Chem; 2010 Feb; 285(7):5097-105. PubMed ID: 20007693
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Impaired helix 12 dynamics due to proline 892 substitutions in the androgen receptor are associated with complete androgen insensitivity.
    Elhaji YA; Stoica I; Dennis S; Purisima EO; Lumbroso R; Beitel LK; Trifiro MA
    Hum Mol Genet; 2006 Mar; 15(6):921-31. PubMed ID: 16449235
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An investigation into CAG repeat length variation and N/C terminal interactions in the T877A mutant androgen receptor found in prostate cancer.
    Southwell J; Chowdhury SF; Gottlieb B; Beitel LK; Lumbroso R; Purisima EO; Trifiro M
    J Steroid Biochem Mol Biol; 2008 Jul; 111(1-2):138-46. PubMed ID: 18619542
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Broadened ligand responsiveness of androgen receptor mutants obtained by random amino acid substitution of H874 and mutation hot spot T877 in prostate cancer.
    Steketee K; Timmerman L; Ziel-van der Made AC; Doesburg P; Brinkmann AO; Trapman J
    Int J Cancer; 2002 Jul; 100(3):309-17. PubMed ID: 12115546
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.