351 related articles for article (PubMed ID: 17314092)
1. Cdc6 ATPase activity regulates ORC x Cdc6 stability and the selection of specific DNA sequences as origins of DNA replication.
Speck C; Stillman B
J Biol Chem; 2007 Apr; 282(16):11705-14. PubMed ID: 17314092
[TBL] [Abstract][Full Text] [Related]
2. The structure of ORC-Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6.
Feng X; Noguchi Y; Barbon M; Stillman B; Speck C; Li H
Nat Commun; 2021 Jun; 12(1):3883. PubMed ID: 34162887
[TBL] [Abstract][Full Text] [Related]
3. In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2-7 hexamer dimerization.
Evrin C; Fernández-Cid A; Zech J; Herrera MC; Riera A; Clarke P; Brill S; Lurz R; Speck C
Nucleic Acids Res; 2013 Mar; 41(5):3162-72. PubMed ID: 23376927
[TBL] [Abstract][Full Text] [Related]
4. Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Yuan Z; Schneider S; Dodd T; Riera A; Bai L; Yan C; Magdalou I; Ivanov I; Stillman B; Li H; Speck C
Proc Natl Acad Sci U S A; 2020 Jul; 117(30):17747-17756. PubMed ID: 32669428
[TBL] [Abstract][Full Text] [Related]
5. An ORC/Cdc6/MCM2-7 complex is formed in a multistep reaction to serve as a platform for MCM double-hexamer assembly.
Fernández-Cid A; Riera A; Tognetti S; Herrera MC; Samel S; Evrin C; Winkler C; Gardenal E; Uhle S; Speck C
Mol Cell; 2013 May; 50(4):577-88. PubMed ID: 23603117
[TBL] [Abstract][Full Text] [Related]
6. Cdc6 ATPase activity disengages Cdc6 from the pre-replicative complex to promote DNA replication.
Chang F; Riera A; Evrin C; Sun J; Li H; Speck C; Weinreich M
Elife; 2015 Aug; 4():. PubMed ID: 26305410
[TBL] [Abstract][Full Text] [Related]
7. ATPase-dependent cooperative binding of ORC and Cdc6 to origin DNA.
Speck C; Chen Z; Li H; Stillman B
Nat Struct Mol Biol; 2005 Nov; 12(11):965-71. PubMed ID: 16228006
[TBL] [Abstract][Full Text] [Related]
8. Sequential ATP hydrolysis by Cdc6 and ORC directs loading of the Mcm2-7 helicase.
Randell JC; Bowers JL; Rodríguez HK; Bell SP
Mol Cell; 2006 Jan; 21(1):29-39. PubMed ID: 16387651
[TBL] [Abstract][Full Text] [Related]
9. DNA replication origins retain mobile licensing proteins.
Sánchez H; McCluskey K; van Laar T; van Veen E; Asscher FM; Solano B; Diffley JFX; Dekker NH
Nat Commun; 2021 Mar; 12(1):1908. PubMed ID: 33772005
[TBL] [Abstract][Full Text] [Related]
10. Dynamics of DNA binding of replication initiation proteins during de novo formation of pre-replicative complexes in Xenopus egg extracts.
Waga S; Zembutsu A
J Biol Chem; 2006 Apr; 281(16):10926-34. PubMed ID: 16497662
[TBL] [Abstract][Full Text] [Related]
11. A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.
Schmidt JM; Yang R; Kumar A; Hunker O; Seebacher J; Bleichert F
Nat Commun; 2022 Feb; 13(1):1059. PubMed ID: 35217664
[TBL] [Abstract][Full Text] [Related]
12. Analysis of mutant origin recognition complex with reduced ATPase activity in vivo and in vitro.
Takehara M; Makise M; Takenaka H; Asano T; Mizushima T
Biochem J; 2008 Aug; 413(3):535-43. PubMed ID: 18393942
[TBL] [Abstract][Full Text] [Related]
13. Origin licensing requires ATP binding and hydrolysis by the MCM replicative helicase.
Coster G; Frigola J; Beuron F; Morris EP; Diffley JF
Mol Cell; 2014 Sep; 55(5):666-77. PubMed ID: 25087873
[TBL] [Abstract][Full Text] [Related]
14. MCM interference during licensing of DNA replication in Xenopus egg extracts-Possible Role of a C-terminal region of MCM3.
Mimura S; Kubota Y; Takisawa H
Cell Cycle; 2018; 17(4):492-505. PubMed ID: 29261034
[TBL] [Abstract][Full Text] [Related]
15. Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1.
Yuan Z; Riera A; Bai L; Sun J; Nandi S; Spanos C; Chen ZA; Barbon M; Rappsilber J; Stillman B; Speck C; Li H
Nat Struct Mol Biol; 2017 Mar; 24(3):316-324. PubMed ID: 28191893
[TBL] [Abstract][Full Text] [Related]
16. Regulation of replication origin licensing by ORC phosphorylation reveals a two-step mechanism for Mcm2-7 ring closing.
Amasino AL; Gupta S; Friedman LJ; Gelles J; Bell SP
Proc Natl Acad Sci U S A; 2023 Jul; 120(29):e2221484120. PubMed ID: 37428921
[TBL] [Abstract][Full Text] [Related]
17. Two subunits of human ORC are dispensable for DNA replication and proliferation.
Shibata E; Kiran M; Shibata Y; Singh S; Kiran S; Dutta A
Elife; 2016 Dec; 5():. PubMed ID: 27906128
[TBL] [Abstract][Full Text] [Related]
18. A helicase-tethered ORC flip enables bidirectional helicase loading.
Gupta S; Friedman LJ; Gelles J; Bell SP
Elife; 2021 Dec; 10():. PubMed ID: 34882090
[TBL] [Abstract][Full Text] [Related]
19. The dynamics of eukaryotic replication initiation: origin specificity, licensing, and firing at the single-molecule level.
Duzdevich D; Warner MD; Ticau S; Ivica NA; Bell SP; Greene EC
Mol Cell; 2015 May; 58(3):483-94. PubMed ID: 25921072
[TBL] [Abstract][Full Text] [Related]
20. Cyclin A-dependent kinase activity affects chromatin binding of ORC, Cdc6, and MCM in egg extracts of Xenopus laevis.
Findeisen M; El-Denary M; Kapitza T; Graf R; Strausfeld U
Eur J Biochem; 1999 Sep; 264(2):415-26. PubMed ID: 10491086
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
