These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
129 related articles for article (PubMed ID: 17314102)
1. MADD/DENN splice variant of the IG20 gene is a negative regulator of caspase-8 activation. Knockdown enhances TRAIL-induced apoptosis of cancer cells. Mulherkar N; Prasad KV; Prabhakar BS J Biol Chem; 2007 Apr; 282(16):11715-21. PubMed ID: 17314102 [TBL] [Abstract][Full Text] [Related]
2. IG20 (MADD splice variant-5), a proapoptotic protein, interacts with DR4/DR5 and enhances TRAIL-induced apoptosis by increasing recruitment of FADD and caspase-8 to the DISC. Ramaswamy M; Efimova EV; Martinez O; Mulherkar NU; Singh SP; Prabhakar BS Oncogene; 2004 Aug; 23(36):6083-94. PubMed ID: 15208670 [TBL] [Abstract][Full Text] [Related]
3. Contrasting effects of IG20 and its splice isoforms, MADD and DENN-SV, on tumor necrosis factor alpha-induced apoptosis and activation of caspase-8 and -3. Al-Zoubi AM; Efimova EV; Kaithamana S; Martinez O; El-Idrissi Mel-A; Dogan RE; Prabhakar BS J Biol Chem; 2001 Dec; 276(50):47202-11. PubMed ID: 11577081 [TBL] [Abstract][Full Text] [Related]
4. Down-modulation of expression, or dephosphorylation, of IG20/MADD in tumor necrosis factor-related apoptosis-inducing ligand-resistant thyroid cancer cells makes them susceptible to treatment with this ligand. Li LC; Jayarama S; Pilli T; Qian L; Pacini F; Prabhakar BS Thyroid; 2013 Jan; 23(1):70-8. PubMed ID: 22998497 [TBL] [Abstract][Full Text] [Related]
5. MADD/DENN splice variant of the IG20 gene is necessary and sufficient for cancer cell survival. Mulherkar N; Ramaswamy M; Mordi DC; Prabhakar BS Oncogene; 2006 Oct; 25(47):6252-61. PubMed ID: 16682944 [TBL] [Abstract][Full Text] [Related]
6. Role of IG20 splice variants in TRAIL resistance. Prabhakar BS; Mulherkar N; Prasad KV Clin Cancer Res; 2008 Jan; 14(2):347-51. PubMed ID: 18223207 [TBL] [Abstract][Full Text] [Related]
7. MADD, a splice variant of IG20, is indispensable for MAPK activation and protection against apoptosis upon tumor necrosis factor-alpha treatment. Kurada BRVVSN; Li LC; Mulherkar N; Subramanian M; Prasad KV; Prabhakar BS J Biol Chem; 2009 May; 284(20):13533-13541. PubMed ID: 19289468 [TBL] [Abstract][Full Text] [Related]
8. IG20, in contrast to DENN-SV, (MADD splice variants) suppresses tumor cell survival, and enhances their susceptibility to apoptosis and cancer drugs. Efimova EV; Al-Zoubi AM; Martinez O; Kaithamana S; Lu S; Arima T; Prabhakar BS Oncogene; 2004 Feb; 23(5):1076-87. PubMed ID: 14716293 [TBL] [Abstract][Full Text] [Related]
9. IG20, a MADD splice variant, increases cell susceptibility to gamma-irradiation and induces soluble mediators that suppress tumor cell growth. Efimova E; Martinez O; Lokshin A; Arima T; Prabhakar BS Cancer Res; 2003 Dec; 63(24):8768-76. PubMed ID: 14695193 [TBL] [Abstract][Full Text] [Related]
10. Akt-phosphorylated mitogen-activated kinase-activating death domain protein (MADD) inhibits TRAIL-induced apoptosis by blocking Fas-associated death domain (FADD) association with death receptor 4. Li P; Jayarama S; Ganesh L; Mordi D; Carr R; Kanteti P; Hay N; Prabhakar BS J Biol Chem; 2010 Jul; 285(29):22713-22. PubMed ID: 20484047 [TBL] [Abstract][Full Text] [Related]
11. MADD knock-down enhances doxorubicin and TRAIL induced apoptosis in breast cancer cells. Turner A; Li LC; Pilli T; Qian L; Wiley EL; Setty S; Christov K; Ganesh L; Maker AV; Li P; Kanteti P; Das Gupta TK; Prabhakar BS PLoS One; 2013; 8(2):e56817. PubMed ID: 23457619 [TBL] [Abstract][Full Text] [Related]
12. Regulation of apoptosis and caspase-8 expression in neuroblastoma cells by isoforms of the IG20 gene. Li LC; Sheng JR; Mulherkar N; Prabhakar BS; Meriggioli MN Cancer Res; 2008 Sep; 68(18):7352-61. PubMed ID: 18794122 [TBL] [Abstract][Full Text] [Related]
13. Knockdown of MADD and c-FLIP overcomes resistance to TRAIL-induced apoptosis in ovarian cancer cells. Li LC; Jayaram S; Ganesh L; Qian L; Rotmensch J; Maker AV; Prabhakar BS Am J Obstet Gynecol; 2011 Oct; 205(4):362.e12-25. PubMed ID: 21855847 [TBL] [Abstract][Full Text] [Related]
14. DENN/MADD/IG20 alternative splicing changes and cell death in Alzheimer's disease. Mo Y; Williams C; Miller CA J Mol Neurosci; 2012 Sep; 48(1):97-110. PubMed ID: 22678883 [TBL] [Abstract][Full Text] [Related]
15. TRAIL suppresses human breast cancer cell migration via MADD/CXCR7. Wang R; Li JC Asian Pac J Cancer Prev; 2015; 16(7):2751-6. PubMed ID: 25854358 [TBL] [Abstract][Full Text] [Related]