These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 17314102)

  • 1. MADD/DENN splice variant of the IG20 gene is a negative regulator of caspase-8 activation. Knockdown enhances TRAIL-induced apoptosis of cancer cells.
    Mulherkar N; Prasad KV; Prabhakar BS
    J Biol Chem; 2007 Apr; 282(16):11715-21. PubMed ID: 17314102
    [TBL] [Abstract][Full Text] [Related]  

  • 2. IG20 (MADD splice variant-5), a proapoptotic protein, interacts with DR4/DR5 and enhances TRAIL-induced apoptosis by increasing recruitment of FADD and caspase-8 to the DISC.
    Ramaswamy M; Efimova EV; Martinez O; Mulherkar NU; Singh SP; Prabhakar BS
    Oncogene; 2004 Aug; 23(36):6083-94. PubMed ID: 15208670
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Contrasting effects of IG20 and its splice isoforms, MADD and DENN-SV, on tumor necrosis factor alpha-induced apoptosis and activation of caspase-8 and -3.
    Al-Zoubi AM; Efimova EV; Kaithamana S; Martinez O; El-Idrissi Mel-A; Dogan RE; Prabhakar BS
    J Biol Chem; 2001 Dec; 276(50):47202-11. PubMed ID: 11577081
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Down-modulation of expression, or dephosphorylation, of IG20/MADD in tumor necrosis factor-related apoptosis-inducing ligand-resistant thyroid cancer cells makes them susceptible to treatment with this ligand.
    Li LC; Jayarama S; Pilli T; Qian L; Pacini F; Prabhakar BS
    Thyroid; 2013 Jan; 23(1):70-8. PubMed ID: 22998497
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MADD/DENN splice variant of the IG20 gene is necessary and sufficient for cancer cell survival.
    Mulherkar N; Ramaswamy M; Mordi DC; Prabhakar BS
    Oncogene; 2006 Oct; 25(47):6252-61. PubMed ID: 16682944
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of IG20 splice variants in TRAIL resistance.
    Prabhakar BS; Mulherkar N; Prasad KV
    Clin Cancer Res; 2008 Jan; 14(2):347-51. PubMed ID: 18223207
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MADD, a splice variant of IG20, is indispensable for MAPK activation and protection against apoptosis upon tumor necrosis factor-alpha treatment.
    Kurada BRVVSN; Li LC; Mulherkar N; Subramanian M; Prasad KV; Prabhakar BS
    J Biol Chem; 2009 May; 284(20):13533-13541. PubMed ID: 19289468
    [TBL] [Abstract][Full Text] [Related]  

  • 8. IG20, in contrast to DENN-SV, (MADD splice variants) suppresses tumor cell survival, and enhances their susceptibility to apoptosis and cancer drugs.
    Efimova EV; Al-Zoubi AM; Martinez O; Kaithamana S; Lu S; Arima T; Prabhakar BS
    Oncogene; 2004 Feb; 23(5):1076-87. PubMed ID: 14716293
    [TBL] [Abstract][Full Text] [Related]  

  • 9. IG20, a MADD splice variant, increases cell susceptibility to gamma-irradiation and induces soluble mediators that suppress tumor cell growth.
    Efimova E; Martinez O; Lokshin A; Arima T; Prabhakar BS
    Cancer Res; 2003 Dec; 63(24):8768-76. PubMed ID: 14695193
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Akt-phosphorylated mitogen-activated kinase-activating death domain protein (MADD) inhibits TRAIL-induced apoptosis by blocking Fas-associated death domain (FADD) association with death receptor 4.
    Li P; Jayarama S; Ganesh L; Mordi D; Carr R; Kanteti P; Hay N; Prabhakar BS
    J Biol Chem; 2010 Jul; 285(29):22713-22. PubMed ID: 20484047
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MADD knock-down enhances doxorubicin and TRAIL induced apoptosis in breast cancer cells.
    Turner A; Li LC; Pilli T; Qian L; Wiley EL; Setty S; Christov K; Ganesh L; Maker AV; Li P; Kanteti P; Das Gupta TK; Prabhakar BS
    PLoS One; 2013; 8(2):e56817. PubMed ID: 23457619
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of apoptosis and caspase-8 expression in neuroblastoma cells by isoforms of the IG20 gene.
    Li LC; Sheng JR; Mulherkar N; Prabhakar BS; Meriggioli MN
    Cancer Res; 2008 Sep; 68(18):7352-61. PubMed ID: 18794122
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Knockdown of MADD and c-FLIP overcomes resistance to TRAIL-induced apoptosis in ovarian cancer cells.
    Li LC; Jayaram S; Ganesh L; Qian L; Rotmensch J; Maker AV; Prabhakar BS
    Am J Obstet Gynecol; 2011 Oct; 205(4):362.e12-25. PubMed ID: 21855847
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DENN/MADD/IG20 alternative splicing changes and cell death in Alzheimer's disease.
    Mo Y; Williams C; Miller CA
    J Mol Neurosci; 2012 Sep; 48(1):97-110. PubMed ID: 22678883
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TRAIL suppresses human breast cancer cell migration via MADD/CXCR7.
    Wang R; Li JC
    Asian Pac J Cancer Prev; 2015; 16(7):2751-6. PubMed ID: 25854358
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Knockdown of IG20 gene expression renders thyroid cancer cells susceptible to apoptosis.
    Subramanian M; Pilli T; Bhattacharya P; Pacini F; Nikiforov YE; Kanteti PV; Prabhakar BS
    J Clin Endocrinol Metab; 2009 Apr; 94(4):1467-71. PubMed ID: 19190106
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Protein kinase C modulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by targeting the apical events of death receptor signaling.
    Harper N; Hughes MA; Farrow SN; Cohen GM; MacFarlane M
    J Biol Chem; 2003 Nov; 278(45):44338-47. PubMed ID: 12920112
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs.
    Ganten TM; Haas TL; Sykora J; Stahl H; Sprick MR; Fas SC; Krueger A; Weigand MA; Grosse-Wilde A; Stremmel W; Krammer PH; Walczak H
    Cell Death Differ; 2004 Jul; 11 Suppl 1():S86-96. PubMed ID: 15105837
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MADD silencing enhances anti-tumor activity of TRAIL in anaplastic thyroid cancer.
    Saini S; Sripada L; Tulla K; Qiao G; Kunda N; Maker AV; Prabhakar BS
    Endocr Relat Cancer; 2019 Jun; 26(6):551-563. PubMed ID: 30999276
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MADD promotes the survival of human lung adenocarcinoma cells by inhibiting apoptosis.
    Bi W; Wei Y; Wu J; Sun G; Guo Y; Zhang Q; Dong L
    Oncol Rep; 2013 Apr; 29(4):1533-9. PubMed ID: 23443411
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.