BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

292 related articles for article (PubMed ID: 17314319)

  • 1. Extracellular signal-regulated kinase is an endogenous signal retaining the nuclear constitutive active/androstane receptor (CAR) in the cytoplasm of mouse primary hepatocytes.
    Koike C; Moore R; Negishi M
    Mol Pharmacol; 2007 May; 71(5):1217-21. PubMed ID: 17314319
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Stilbene compound trans-3,4,5,4ยด-tetramethoxystilbene, a potential anticancer drug, regulates constitutive androstane receptor (Car) target genes, but does not possess proliferative activity in mouse liver.
    Dusek J; Skoda J; Holas O; Horvatova A; Smutny T; Linhartova L; Hirsova P; Kucera O; Micuda S; Braeuning A; Pavek P
    Toxicol Lett; 2019 Oct; 313():1-10. PubMed ID: 31170421
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protein Kinase N Family Negatively Regulates Constitutive Androstane Receptor-Mediated Transcriptional Induction of Cytochrome P450 2b10 in the Livers of Mice.
    Kawase A; Mukai H; Tateishi S; Kuroda S; Kazaoka A; Satoh R; Shimada H; Sugiura R; Iwaki M
    J Pharmacol Exp Ther; 2021 Oct; 379(1):53-63. PubMed ID: 34312179
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Retinoic acids repress constitutive active receptor-mediated induction by 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene of the CYP2B10 gene in mouse primary hepatocytes.
    Kakizaki S; Karami S; Negishi M
    Drug Metab Dispos; 2002 Feb; 30(2):208-11. PubMed ID: 11792692
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response.
    Wei P; Zhang J; Dowhan DH; Han Y; Moore DD
    Pharmacogenomics J; 2002; 2(2):117-26. PubMed ID: 12049174
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of nuclear receptor CAR by an environmental pollutant perfluorooctanoic acid.
    Abe T; Takahashi M; Kano M; Amaike Y; Ishii C; Maeda K; Kudoh Y; Morishita T; Hosaka T; Sasaki T; Kodama S; Matsuzawa A; Kojima H; Yoshinari K
    Arch Toxicol; 2017 Jun; 91(6):2365-2374. PubMed ID: 27832320
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Estrogen activation of the nuclear orphan receptor CAR (constitutive active receptor) in induction of the mouse Cyp2b10 gene.
    Kawamoto T; Kakizaki S; Yoshinari K; Negishi M
    Mol Endocrinol; 2000 Nov; 14(11):1897-905. PubMed ID: 11075820
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Old dance with a new partner: EGF receptor as the phenobarbital receptor mediating Cyp2B expression.
    Meyer SA; Jirtle RL
    Sci Signal; 2013 May; 6(274):pe16. PubMed ID: 23652202
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of gender-dependent CYP2A expression in pigs: involvement of androgens and CAR.
    Gillberg M; Skaanild MT; Friis C
    Basic Clin Pharmacol Toxicol; 2006 May; 98(5):480-7. PubMed ID: 16635107
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Prolonged nuclear retention of activated extracellular signal-regulated kinase 1/2 is required for hepatocyte growth factor-induced cell motility.
    Tanimura S; Nomura K; Ozaki K; Tsujimoto M; Kondo T; Kohno M
    J Biol Chem; 2002 Aug; 277(31):28256-64. PubMed ID: 12032150
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Development of an in vitro high content imaging assay for quantitative assessment of CAR-dependent mouse, rat, and human primary hepatocyte proliferation.
    Soldatow V; Peffer RC; Trask OJ; Cowie DE; Andersen ME; LeCluyse E; Deisenroth C
    Toxicol In Vitro; 2016 Oct; 36():224-237. PubMed ID: 27530964
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Active ERK1/2 protein interacts with the phosphorylated nuclear constitutive active/androstane receptor (CAR; NR1I3), repressing dephosphorylation and sequestering CAR in the cytoplasm.
    Osabe M; Negishi M
    J Biol Chem; 2011 Oct; 286(41):35763-35769. PubMed ID: 21873423
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The role of hepatocyte RXR alpha in xenobiotic-sensing nuclear receptor-mediated pathways.
    Cai Y; Konishi T; Han G; Campwala KH; French SW; Wan YJ
    Eur J Pharm Sci; 2002 Feb; 15(1):89-96. PubMed ID: 11803135
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sterol regulatory element binding protein 1 interacts with pregnane X receptor and constitutive androstane receptor and represses their target genes.
    Roth A; Looser R; Kaufmann M; Meyer UA
    Pharmacogenet Genomics; 2008 Apr; 18(4):325-37. PubMed ID: 18334917
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Induction of UGT1A1 and CYP2B6 by an antimitogenic factor in HepG2 cells is mediated through suppression of cyclin-dependent kinase 2 activity: cell cycle-dependent expression.
    Sugatani J; Osabe M; Kurosawa M; Kitamura N; Ikari A; Miwa M
    Drug Metab Dispos; 2010 Jan; 38(1):177-86. PubMed ID: 19797611
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sex difference in the proliferative response of mouse hepatocytes to treatment with the CAR ligand, TCPOBOP.
    Ledda-Columbano GM; Pibiri M; Concas D; Molotzu F; Simbula G; Cossu C; Columbano A
    Carcinogenesis; 2003 Jun; 24(6):1059-65. PubMed ID: 12807759
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Constitutive androstane receptor activation evokes the expression of glycolytic genes.
    Yarushkin AA; Kazantseva YA; Prokopyeva EA; Markova DN; Pustylnyak YA; Pustylnyak VO
    Biochem Biophys Res Commun; 2016 Sep; 478(3):1099-105. PubMed ID: 27530923
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dexamethasone enhances constitutive androstane receptor expression in human hepatocytes: consequences on cytochrome P450 gene regulation.
    Pascussi JM; Gerbal-Chaloin S; Fabre JM; Maurel P; Vilarem MJ
    Mol Pharmacol; 2000 Dec; 58(6):1441-50. PubMed ID: 11093784
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor alpha synthetic ligands in mouse liver.
    Guo D; Sarkar J; Suino-Powell K; Xu Y; Matsumoto K; Jia Y; Yu S; Khare S; Haldar K; Rao MS; Foreman JE; Monga SP; Peters JM; Xu HE; Reddy JK
    J Biol Chem; 2007 Dec; 282(50):36766-76. PubMed ID: 17962186
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The roles of co-chaperone CCRP/DNAJC7 in Cyp2b10 gene activation and steatosis development in mouse livers.
    Ohno M; Kanayama T; Moore R; Ray M; Negishi M
    PLoS One; 2014; 9(12):e115663. PubMed ID: 25542016
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.