These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 17317574)

  • 1. Apoptosis in T cell acute lymphoblastic leukemia cells after cell cycle arrest induced by pharmacological inhibition of notch signaling.
    Lewis HD; Leveridge M; Strack PR; Haldon CD; O'neil J; Kim H; Madin A; Hannam JC; Look AT; Kohl N; Draetta G; Harrison T; Kerby JA; Shearman MS; Beher D
    Chem Biol; 2007 Feb; 14(2):209-19. PubMed ID: 17317574
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia.
    De Keersmaecker K; Lahortiga I; Mentens N; Folens C; Van Neste L; Bekaert S; Vandenberghe P; Odero MD; Marynen P; Cools J
    Haematologica; 2008 Apr; 93(4):533-42. PubMed ID: 18322257
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Gamma-secretase inhibitors suppress the growth of leukemia and lymphoma cells.
    Kogoshi H; Sato T; Koyama T; Nara N; Tohda S
    Oncol Rep; 2007 Jul; 18(1):77-80. PubMed ID: 17549349
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of gamma-secretase affects proliferation of leukemia and hepatoma cell lines through Notch signaling.
    Suwanjunee S; Wongchana W; Palaga T
    Anticancer Drugs; 2008 Jun; 19(5):477-86. PubMed ID: 18418214
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of NOTCH signaling by gamma secretase inhibitor engages the RB pathway and elicits cell cycle exit in T-cell acute lymphoblastic leukemia cells.
    Rao SS; O'Neil J; Liberator CD; Hardwick JS; Dai X; Zhang T; Tyminski E; Yuan J; Kohl NE; Richon VM; Van der Ploeg LH; Carroll PM; Draetta GF; Look AT; Strack PR; Winter CG
    Cancer Res; 2009 Apr; 69(7):3060-8. PubMed ID: 19318552
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Downregulation of Notch signaling by gamma-secretase inhibition can abrogate chemotherapy-induced apoptosis in T-ALL cell lines.
    Liu S; Breit S; Danckwardt S; Muckenthaler MU; Kulozik AE
    Ann Hematol; 2009 Jul; 88(7):613-21. PubMed ID: 19057901
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Downregulation of Notch pathway by a gamma-secretase inhibitor attenuates AKT/mammalian target of rapamycin signaling and glucose uptake in an ERBB2 transgenic breast cancer model.
    Efferson CL; Winkelmann CT; Ware C; Sullivan T; Giampaoli S; Tammam J; Patel S; Mesiti G; Reilly JF; Gibson RE; Buser C; Yeatman T; Coppola D; Winter C; Clark EA; Draetta GF; Strack PR; Majumder PK
    Cancer Res; 2010 Mar; 70(6):2476-84. PubMed ID: 20197467
    [TBL] [Abstract][Full Text] [Related]  

  • 8. z-Leucinyl-leucinyl-norleucinal induces apoptosis of human glioblastoma tumor-initiating cells by proteasome inhibition and mitotic arrest response.
    Monticone M; Biollo E; Fabiano A; Fabbi M; Daga A; Romeo F; Maffei M; Melotti A; Giaretti W; Corte G; Castagnola P
    Mol Cancer Res; 2009 Nov; 7(11):1822-34. PubMed ID: 19861404
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [Expression of Notch intracellular domain in cervical cancer and effect of DAPT on cervical cancer cell].
    Sun XM; Wen HW; Chen CL; Liao QP
    Zhonghua Fu Chan Ke Za Zhi; 2009 May; 44(5):369-73. PubMed ID: 19573314
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Gamma-secretase inhibitors exerts antitumor activity via down-regulation of Notch and Nuclear factor kappa B in human tongue carcinoma cells.
    Yao J; Duan L; Fan M; Wu X
    Oral Dis; 2007 Nov; 13(6):555-63. PubMed ID: 17944672
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Inhibitors for Notch and gamma-secretase. Biology of T-cell leukemia].
    Yahagi Y; Usui N
    Gan To Kagaku Ryoho; 2009 May; 36(5):744-8. PubMed ID: 19496283
    [No Abstract]   [Full Text] [Related]  

  • 12. Evidence that gamma-secretase-mediated Notch signaling induces neuronal cell death via the nuclear factor-kappaB-Bcl-2-interacting mediator of cell death pathway in ischemic stroke.
    Arumugam TV; Cheng YL; Choi Y; Choi YH; Yang S; Yun YK; Park JS; Yang DK; Thundyil J; Gelderblom M; Karamyan VT; Tang SC; Chan SL; Magnus T; Sobey CG; Jo DG
    Mol Pharmacol; 2011 Jul; 80(1):23-31. PubMed ID: 21450930
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Suppression of the notch signaling pathway by γ-secretase inhibitor GSI inhibits human nasopharyngeal carcinoma cell proliferation.
    Chen SM; Liu JP; Zhou JX; Chen C; Deng YQ; Wang Y; Tao ZZ
    Cancer Lett; 2011 Jul; 306(1):76-84. PubMed ID: 21420785
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Notch-1 regulates Akt signaling pathway and the expression of cell cycle regulatory proteins cyclin D1, CDK2 and p21 in T-ALL cell lines.
    Guo D; Ye J; Dai J; Li L; Chen F; Ma D; Ji C
    Leuk Res; 2009 May; 33(5):678-85. PubMed ID: 19091404
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Begacestat (GSI-953): a novel, selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase for the treatment of Alzheimer's disease.
    Martone RL; Zhou H; Atchison K; Comery T; Xu JZ; Huang X; Gong X; Jin M; Kreft A; Harrison B; Mayer SC; Aschmies S; Gonzales C; Zaleska MM; Riddell DR; Wagner E; Lu P; Sun SC; Sonnenberg-Reines J; Oganesian A; Adkins K; Leach MW; Clarke DW; Huryn D; Abou-Gharbia M; Magolda R; Bard J; Frick G; Raje S; Forlow SB; Balliet C; Burczynski ME; Reinhart PH; Wan HI; Pangalos MN; Jacobsen JS
    J Pharmacol Exp Ther; 2009 Nov; 331(2):598-608. PubMed ID: 19671883
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of Notch signaling reduces the stem-like population of breast cancer cells and prevents mammosphere formation.
    Grudzien P; Lo S; Albain KS; Robinson P; Rajan P; Strack PR; Golde TE; Miele L; Foreman KE
    Anticancer Res; 2010 Oct; 30(10):3853-67. PubMed ID: 21036696
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Notch signaling induces SKP2 expression and promotes reduction of p27Kip1 in T-cell acute lymphoblastic leukemia cell lines.
    Dohda T; Maljukova A; Liu L; Heyman M; Grandér D; Brodin D; Sangfelt O; Lendahl U
    Exp Cell Res; 2007 Aug; 313(14):3141-52. PubMed ID: 17560996
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to gamma-secretase inhibitors.
    Palomero T; Barnes KC; Real PJ; Glade Bender JL; Sulis ML; Murty VV; Colovai AI; Balbin M; Ferrando AA
    Leukemia; 2006 Jul; 20(7):1279-87. PubMed ID: 16688224
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers.
    Konishi J; Kawaguchi KS; Vo H; Haruki N; Gonzalez A; Carbone DP; Dang TP
    Cancer Res; 2007 Sep; 67(17):8051-7. PubMed ID: 17804716
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Unnatural amino acid-substituted (hydroxyethyl)urea peptidomimetics inhibit gamma-secretase and promote the neuronal differentiation of neuroblastoma cells.
    Liao YF; Wang BJ; Hsu WM; Lee H; Liao CY; Wu SY; Cheng HT; Hu MK
    Mol Pharmacol; 2007 Feb; 71(2):588-601. PubMed ID: 17105873
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.