These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

476 related articles for article (PubMed ID: 17317656)

  • 1. Transforming growth factor-beta receptor type I-dependent fibrogenic gene program is mediated via activation of Smad1 and ERK1/2 pathways.
    Pannu J; Nakerakanti S; Smith E; ten Dijke P; Trojanowska M
    J Biol Chem; 2007 Apr; 282(14):10405-13. PubMed ID: 17317656
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Endoglin promotes TGF-β/Smad1 signaling in scleroderma fibroblasts.
    Morris E; Chrobak I; Bujor A; Hant F; Mummery C; Ten Dijke P; Trojanowska M
    J Cell Physiol; 2011 Dec; 226(12):3340-8. PubMed ID: 21344387
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CCN2 is required for the TGF-β induced activation of Smad1-Erk1/2 signaling network.
    Nakerakanti SS; Bujor AM; Trojanowska M
    PLoS One; 2011; 6(7):e21911. PubMed ID: 21760921
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glucocorticoids recruit Tgfbr3 and Smad1 to shift transforming growth factor-β signaling from the Tgfbr1/Smad2/3 axis to the Acvrl1/Smad1 axis in lung fibroblasts.
    Schwartze JT; Becker S; Sakkas E; Wujak ŁA; Niess G; Usemann J; Reichenberger F; Herold S; Vadász I; Mayer K; Seeger W; Morty RE
    J Biol Chem; 2014 Feb; 289(6):3262-75. PubMed ID: 24347165
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transforming growth factor-β stimulates Smad1/5 signaling in pulmonary artery smooth muscle cells and fibroblasts of the newborn mouse through ALK1.
    Zhang H; Du L; Zhong Y; Flanders KC; Roberts JD
    Am J Physiol Lung Cell Mol Physiol; 2017 Sep; 313(3):L615-L627. PubMed ID: 28642261
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Smad1 pathway is activated in systemic sclerosis fibroblasts and is targeted by imatinib mesylate.
    Pannu J; Asano Y; Nakerakanti S; Smith E; Jablonska S; Blaszczyk M; ten Dijke P; Trojanowska M
    Arthritis Rheum; 2008 Aug; 58(8):2528-37. PubMed ID: 18668566
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Growth differentiation factor-9 signaling is mediated by the type I receptor, activin receptor-like kinase 5.
    Mazerbourg S; Klein C; Roh J; Kaivo-Oja N; Mottershead DG; Korchynskyi O; Ritvos O; Hsueh AJ
    Mol Endocrinol; 2004 Mar; 18(3):653-65. PubMed ID: 14684852
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ALK1 opposes ALK5/Smad3 signaling and expression of extracellular matrix components in human chondrocytes.
    Finnson KW; Parker WL; ten Dijke P; Thorikay M; Philip A
    J Bone Miner Res; 2008 Jun; 23(6):896-906. PubMed ID: 18333754
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Attenuation of collagen production with small interfering RNA of SPARC in cultured fibroblasts from the skin of patients with scleroderma.
    Zhou X; Tan FK; Guo X; Arnett FC
    Arthritis Rheum; 2006 Aug; 54(8):2626-31. PubMed ID: 16871529
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TGF-ß induces Lysyl hydroxylase 2b in human synovial osteoarthritic fibroblasts through ALK5 signaling.
    Remst DF; Blaney Davidson EN; Vitters EL; Bank RA; van den Berg WB; van der Kraan PM
    Cell Tissue Res; 2014 Jan; 355(1):163-71. PubMed ID: 24192939
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The immunomodulator FTY720 and its phosphorylated derivative activate the Smad signalling cascade and upregulate connective tissue growth factor and collagen type IV expression in renal mesangial cells.
    Xin C; Ren S; Eberhardt W; Pfeilschifter J; Huwiler A
    Br J Pharmacol; 2006 Jan; 147(2):164-74. PubMed ID: 16299553
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Endoglin differentially modulates antagonistic transforming growth factor-beta1 and BMP-7 signaling.
    Scherner O; Meurer SK; Tihaa L; Gressner AM; Weiskirchen R
    J Biol Chem; 2007 May; 282(19):13934-43. PubMed ID: 17376778
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transforming growth factor-β1 induces type II collagen and aggrecan expression via activation of extracellular signal-regulated kinase 1/2 and Smad2/3 signaling pathways.
    Zhu Y; Tao H; Jin C; Liu Y; Lu X; Hu X; Wang X
    Mol Med Rep; 2015 Oct; 12(4):5573-9. PubMed ID: 26165845
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Elevated expression of cav-1 in a subset of SSc fibroblasts contributes to constitutive Alk1/Smad1 activation.
    Haines P; Hant FN; Lafyatis R; Trojanowska M; Bujor AM
    J Cell Mol Med; 2012 Sep; 16(9):2238-46. PubMed ID: 22277251
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling.
    Goumans MJ; Valdimarsdottir G; Itoh S; Lebrin F; Larsson J; Mummery C; Karlsson S; ten Dijke P
    Mol Cell; 2003 Oct; 12(4):817-28. PubMed ID: 14580334
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways: the role of Smad3.
    Yang F; Chung AC; Huang XR; Lan HY
    Hypertension; 2009 Oct; 54(4):877-84. PubMed ID: 19667256
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions.
    Itoh F; Itoh S; Adachi T; Ichikawa K; Matsumura Y; Takagi T; Festing M; Watanabe T; Weinstein M; Karlsson S; Kato M
    Blood; 2012 May; 119(22):5320-8. PubMed ID: 22498737
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice.
    Blaney Davidson EN; Remst DF; Vitters EL; van Beuningen HM; Blom AB; Goumans MJ; van den Berg WB; van der Kraan PM
    J Immunol; 2009 Jun; 182(12):7937-45. PubMed ID: 19494318
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Smad3 and extracellular signal-regulated kinase 1/2 coordinately mediate transforming growth factor-beta-induced expression of connective tissue growth factor in human fibroblasts.
    Leivonen SK; Häkkinen L; Liu D; Kähäri VM
    J Invest Dermatol; 2005 Jun; 124(6):1162-9. PubMed ID: 15955090
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanisms of TGF-β-induced differentiation in human vascular smooth muscle cells.
    Tang Y; Yang X; Friesel RE; Vary CP; Liaw L
    J Vasc Res; 2011; 48(6):485-94. PubMed ID: 21832838
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.