BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

87 related articles for article (PubMed ID: 17326768)

  • 1. Degradation of nicastrin involves both proteasome and lysosome.
    He G; Qing H; Tong Y; Cai F; Ishiura S; Song W
    J Neurochem; 2007 May; 101(4):982-92. PubMed ID: 17326768
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ubiquitin-proteasome pathway mediates degradation of APH-1.
    He G; Qing H; Cai F; Kwok C; Xu H; Yu G; Bernstein A; Song W
    J Neurochem; 2006 Dec; 99(5):1403-12. PubMed ID: 17059559
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Akt1 phosphorylates Nicastrin to regulate its protein stability and activity.
    Jo EH; Ahn JS; Mo JS; Yoon JH; Ann EJ; Baek HJ; Lee HJ; Kim SH; Kim MY; Park HS
    J Neurochem; 2015 Sep; 134(5):799-810. PubMed ID: 25996556
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Conserved residues in juxtamembrane region of the extracellular domain of nicastrin are essential for gamma-secretase complex formation.
    Walker ES; Martinez M; Wang J; Goate A
    J Neurochem; 2006 Jul; 98(1):300-9. PubMed ID: 16805816
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Neprilysin activity and expression are controlled by nicastrin.
    Pardossi-Piquard R; Dunys J; Yu G; St George-Hyslop P; Alves da Costa C; Checler F
    J Neurochem; 2006 May; 97(4):1052-6. PubMed ID: 16606360
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphorylation of nicastrin by SGK1 leads to its degradation through lysosomal and proteasomal pathways.
    Mo JS; Yoon JH; Hong JA; Kim MY; Ann EJ; Ahn JS; Kim SM; Baek HJ; Lang F; Choi EJ; Park HS
    PLoS One; 2012; 7(5):e37111. PubMed ID: 22590650
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Purification, pharmacological modulation, and biochemical characterization of interactors of endogenous human gamma-secretase.
    Winkler E; Hobson S; Fukumori A; Dümpelfeld B; Luebbers T; Baumann K; Haass C; Hopf C; Steiner H
    Biochemistry; 2009 Feb; 48(6):1183-97. PubMed ID: 19159235
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacological evidences for DFK167-sensitive presenilin-independent gamma-secretase-like activity.
    Sevalle J; Ayral E; Hernandez JF; Martinez J; Checler F
    J Neurochem; 2009 Jul; 110(1):275-83. PubMed ID: 19457123
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rat nicastrin gene: cDNA isolation, mRNA variants and expression pattern analysis.
    Confaloni A; Crestini A; Albani D; Piscopo P; Campeggi LM; Terreni L; Tartaglia M; Forloni G
    Brain Res Mol Brain Res; 2005 May; 136(1-2):12-22. PubMed ID: 15893582
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Study on the putative contribution of caspases and the proteasome to the degradation of Aph-1a and Pen-2.
    Dunys J; Kawarai T; Giaime E; Wilk S; Herrant M; Auberger P; St George-Hyslop P; Alves da Costa C; Checler F
    Neurodegener Dis; 2007; 4(2-3):156-63. PubMed ID: 17596710
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cellular localization of Nicastrin affects amyloid beta species production.
    Morais VA; Leight S; Pijak DS; Lee VM; Costa J
    FEBS Lett; 2008 Feb; 582(3):427-33. PubMed ID: 18201567
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nicastrin expression in mouse peripheral tissues is not co-ordinated with presenilin and is high in muscle.
    Ilaya NT; Evin G; Masters CL; Culvenor JG
    J Neurochem; 2004 Oct; 91(1):230-7. PubMed ID: 15379903
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Increased expression of the gamma-secretase components presenilin-1 and nicastrin in activated astrocytes and microglia following traumatic brain injury.
    Nadler Y; Alexandrovich A; Grigoriadis N; Hartmann T; Rao KS; Shohami E; Stein R
    Glia; 2008 Apr; 56(5):552-67. PubMed ID: 18240300
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid beta-protein.
    Maeda T; Marutani T; Zou K; Araki W; Tanabe C; Yagishita N; Yamano Y; Amano T; Michikawa M; Nakajima T; Komano H
    FEBS J; 2009 Oct; 276(20):5832-40. PubMed ID: 19725872
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TMP21 degradation is mediated by the ubiquitin-proteasome pathway.
    Liu S; Bromley-Brits K; Xia K; Mittelholtz J; Wang R; Song W
    Eur J Neurosci; 2008 Nov; 28(10):1980-8. PubMed ID: 19046380
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Alzheimer's disease-associated gamma-secretase complex: functional domains in the presenilin 1 protein.
    Laudon H; Winblad B; Näslund J
    Physiol Behav; 2007 Sep; 92(1-2):115-20. PubMed ID: 17588625
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nicastrin is required for amyloid precursor protein (APP) but not Notch processing, while anterior pharynx-defective 1 is dispensable for processing of both APP and Notch.
    Hu C; Zeng L; Li T; Meyer MA; Cui MZ; Xu X
    J Neurochem; 2016 Mar; 136(6):1246-1258. PubMed ID: 26717550
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transient abundance of presenilin 1 fragments/nicastrin complex associated with synaptogenesis during development in rat cerebellum.
    Uchihara T; Sanjo N; Nakamura A; Han K; Song SY; St George-Hyslop P; Fraser PE
    Neurobiol Aging; 2006 Jan; 27(1):88-97. PubMed ID: 16298244
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The effects of lysosomal and proteasomal inhibitors on abnormal forms of prion protein degradation in murine macrophages.
    Sassa Y; Yamasaki T; Horiuchi M; Inoshima Y; Ishiguro N
    Microbiol Immunol; 2010 Dec; 54(12):763-8. PubMed ID: 21223366
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sodium selenite inhibits gamma-secretase activity through activation of ERK.
    Tung YT; Hsu WM; Wang BJ; Wu SY; Yen CT; Hu MK; Liao YF
    Neurosci Lett; 2008 Jul; 440(1):38-43. PubMed ID: 18547722
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.