BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

110 related articles for article (PubMed ID: 17332142)

  • 1. Evaluation of 3-O-methylfluorescein as a selective fluorometric substrate for CYP2C19 in human liver microsomes.
    Sudsakorn S; Skell J; Williams DA; O'Shea TJ; Liu H
    Drug Metab Dispos; 2007 Jun; 35(6):841-7. PubMed ID: 17332142
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cytochrome P450 2C9 catalyzes indomethacin O-demethylation in human liver microsomes.
    Nakajima M; Inoue T; Shimada N; Tokudome S; Yamamoto T; Kuroiwa Y
    Drug Metab Dispos; 1998 Mar; 26(3):261-6. PubMed ID: 9492390
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Diazinon is activated by CYP2C19 in human liver.
    Kappers WA; Edwards RJ; Murray S; Boobis AR
    Toxicol Appl Pharmacol; 2001 Nov; 177(1):68-76. PubMed ID: 11708902
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Validation of (-)-N-3-benzyl-phenobarbital as a selective inhibitor of CYP2C19 in human liver microsomes.
    Cai X; Wang RW; Edom RW; Evans DC; Shou M; Rodrigues AD; Liu W; Dean DC; Baillie TA
    Drug Metab Dispos; 2004 Jun; 32(6):584-6. PubMed ID: 15155548
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interactions between CYP2C9 and CYP2C19 in reconstituted binary systems influence their catalytic activity: possible rationale for the inability of CYP2C19 to catalyze methoxychlor demethylation in human liver microsomes.
    Hazai E; Kupfer D
    Drug Metab Dispos; 2005 Jan; 33(1):157-64. PubMed ID: 15486075
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human cytochrome P450-catalyzed conversion of the proestrogenic pesticide methoxychlor into an estrogen. Role of CYP2C19 and CYP1A2 in O-demethylation.
    Stresser DM; Kupfer D
    Drug Metab Dispos; 1998 Sep; 26(9):868-74. PubMed ID: 9733665
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes.
    Yao HT; Chang YW; Lan SJ; Chen CT; Hsu JT; Yeh TK
    Life Sci; 2006 Nov; 79(26):2432-40. PubMed ID: 16978661
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metabolism of 18-methoxycoronaridine, an ibogaine analog, to 18-hydroxycoronaridine by genetically variable CYP2C19.
    Zhang W; Ramamoorthy Y; Tyndale RF; Glick SD; Maisonneuve IM; Kuehne ME; Sellers EM
    Drug Metab Dispos; 2002 Jun; 30(6):663-9. PubMed ID: 12019193
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of CYP2C19 and CYP2C9 from human liver: respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations.
    Lasker JM; Wester MR; Aramsombatdee E; Raucy JL
    Arch Biochem Biophys; 1998 May; 353(1):16-28. PubMed ID: 9578596
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vitro sulfoxidation of thioether compounds by human cytochrome P450 and flavin-containing monooxygenase isoforms with particular reference to the CYP2C subfamily.
    Usmani KA; Karoly ED; Hodgson E; Rose RL
    Drug Metab Dispos; 2004 Mar; 32(3):333-9. PubMed ID: 14977868
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of cytochrome P450 enzymes involved in the metabolism of 4'-methoxy-alpha-pyrrolidinopropiophenone (MOPPP), a designer drug, in human liver microsomes.
    Springer D; Staack RF; Paul LD; Kraemer T; Maurer HH
    Xenobiotica; 2003 Oct; 33(10):989-98. PubMed ID: 14555336
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human N-demethylation of (S)-mephenytoin by cytochrome P450s 2C9 and 2B6.
    Ko JW; Desta Z; Flockhart DA
    Drug Metab Dispos; 1998 Aug; 26(8):775-8. PubMed ID: 9698292
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of cytochrome P450 (CYP450) isoforms by isoniazid: potent inhibition of CYP2C19 and CYP3A.
    Desta Z; Soukhova NV; Flockhart DA
    Antimicrob Agents Chemother; 2001 Feb; 45(2):382-92. PubMed ID: 11158730
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Formation of (R)-8-hydroxywarfarin in human liver microsomes. A new metabolic marker for the (S)-mephenytoin hydroxylase, P4502C19.
    Wienkers LC; Wurden CJ; Storch E; Kunze KL; Rettie AE; Trager WF
    Drug Metab Dispos; 1996 May; 24(5):610-4. PubMed ID: 8723744
    [TBL] [Abstract][Full Text] [Related]  

  • 15. (+)-N-3-Benzyl-nirvanol and (-)-N-3-benzyl-phenobarbital: new potent and selective in vitro inhibitors of CYP2C19.
    Suzuki H; Kneller MB; Haining RL; Trager WF; Rettie AE
    Drug Metab Dispos; 2002 Mar; 30(3):235-9. PubMed ID: 11854139
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vitro characterization of clobazam metabolism by recombinant cytochrome P450 enzymes: importance of CYP2C19.
    Giraud C; Tran A; Rey E; Vincent J; Tréluyer JM; Pons G
    Drug Metab Dispos; 2004 Nov; 32(11):1279-86. PubMed ID: 15483195
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interaction of delavirdine with human liver microsomal cytochrome P450: inhibition of CYP2C9, CYP2C19, and CYP2D6.
    Voorman RL; Payne NA; Wienkers LC; Hauer MJ; Sanders PE
    Drug Metab Dispos; 2001 Jan; 29(1):41-7. PubMed ID: 11124228
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evidence for involvement of polymorphic CYP2C19 and 2C9 in the N-demethylation of sertraline in human liver microsomes.
    Xu ZH; Wang W; Zhao XJ; Huang SL; Zhu B; He N; Shu Y; Liu ZQ; Zhou HH
    Br J Clin Pharmacol; 1999 Sep; 48(3):416-23. PubMed ID: 10510155
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human CYP2C19 is a major omeprazole 5-hydroxylase, as demonstrated with recombinant cytochrome P450 enzymes.
    Karam WG; Goldstein JA; Lasker JM; Ghanayem BI
    Drug Metab Dispos; 1996 Oct; 24(10):1081-7. PubMed ID: 8894508
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Chlorpropamide 2-hydroxylation is catalysed by CYP2C9 and CYP2C19 in vitro: chlorpropamide disposition is influenced by CYP2C9, but not by CYP2C19 genetic polymorphism.
    Shon JH; Yoon YR; Kim MJ; Kim KA; Lim YC; Liu KH; Shin DH; Lee CH; Cha IJ; Shin JG
    Br J Clin Pharmacol; 2005 May; 59(5):552-63. PubMed ID: 15842554
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.