408 related articles for article (PubMed ID: 17332326)
21. A network of substrates of the E3 ubiquitin ligases MDM2 and HUWE1 control apoptosis independently of p53.
Kurokawa M; Kim J; Geradts J; Matsuura K; Liu L; Ran X; Xia W; Ribar TJ; Henao R; Dewhirst MW; Kim WJ; Lucas JE; Wang S; Spector NL; Kornbluth S
Sci Signal; 2013 May; 6(274):ra32. PubMed ID: 23652204
[TBL] [Abstract][Full Text] [Related]
22. Curcumin dually inhibits both mammalian target of rapamycin and nuclear factor-κB pathways through a crossed phosphatidylinositol 3-kinase/Akt/IκB kinase complex signaling axis in adenoid cystic carcinoma.
Sun ZJ; Chen G; Zhang W; Hu X; Liu Y; Zhou Q; Zhu LX; Zhao YF
Mol Pharmacol; 2011 Jan; 79(1):106-18. PubMed ID: 20959361
[TBL] [Abstract][Full Text] [Related]
23. p21 Waf1/Cip1 expression by curcumin in U-87MG human glioma cells: role of early growth response-1 expression.
Choi BH; Kim CG; Bae YS; Lim Y; Lee YH; Shin SY
Cancer Res; 2008 Mar; 68(5):1369-77. PubMed ID: 18316600
[TBL] [Abstract][Full Text] [Related]
24. Murine double minute 2 siRNA and wild-type p53 gene therapy interact positively with zinc on prostate tumours in vitro and in vivo.
Gu J; Wang B; Liu Y; Zhong L; Tang Y; Guo H; Jiang T; Wang L; Li Y; Cai L
Eur J Cancer; 2014 Apr; 50(6):1184-94. PubMed ID: 24447832
[TBL] [Abstract][Full Text] [Related]
25. Platycodin D, a metabolite of Platycodin grandiflorum, inhibits highly metastatic MDA-MB-231 breast cancer growth in vitro and in vivo by targeting the MDM2 oncogene.
Kong Y; Lu ZL; Wang JJ; Zhou R; Guo J; Liu J; Sun HL; Wang H; Song W; Yang J; Xu HX
Oncol Rep; 2016 Sep; 36(3):1447-56. PubMed ID: 27432230
[TBL] [Abstract][Full Text] [Related]
26. Downregulation of p53 by phosphatase of regenerating liver 3 is mediated by MDM2 and PIRH2.
Min SH; Kim DM; Heo YS; Kim HM; Kim IC; Yoo OJ
Life Sci; 2010 Jan; 86(1-2):66-72. PubMed ID: 19945467
[TBL] [Abstract][Full Text] [Related]
27. Oroxylin A promotes PTEN-mediated negative regulation of MDM2 transcription via SIRT3-mediated deacetylation to stabilize p53 and inhibit glycolysis in wt-p53 cancer cells.
Zhao K; Zhou Y; Qiao C; Ni T; Li Z; Wang X; Guo Q; Lu N; Wei L
J Hematol Oncol; 2015 Apr; 8():41. PubMed ID: 25902914
[TBL] [Abstract][Full Text] [Related]
28. Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy.
Tovar C; Rosinski J; Filipovic Z; Higgins B; Kolinsky K; Hilton H; Zhao X; Vu BT; Qing W; Packman K; Myklebost O; Heimbrook DC; Vassilev LT
Proc Natl Acad Sci U S A; 2006 Feb; 103(6):1888-93. PubMed ID: 16443686
[TBL] [Abstract][Full Text] [Related]
29. Curcumin regulates proliferation, autophagy, and apoptosis in gastric cancer cells by affecting PI3K and P53 signaling.
Fu H; Wang C; Yang D; Wei Z; Xu J; Hu Z; Zhang Y; Wang W; Yan R; Cai Q
J Cell Physiol; 2018 Jun; 233(6):4634-4642. PubMed ID: 28926094
[TBL] [Abstract][Full Text] [Related]
30. The oncoprotein HBXIP promotes human breast cancer growth through down-regulating p53 via miR-18b/MDM2 and pAKT/MDM2 pathways.
Li H; Wang Z; Jiang M; Fang RP; Shi H; Shen Y; Cai XL; Liu Q; Ye K; Fan SJ; Zhang WY; Ye LH
Acta Pharmacol Sin; 2018 Nov; 39(11):1787-1796. PubMed ID: 30181579
[TBL] [Abstract][Full Text] [Related]
31. Curcumin induces autophagy, inhibits proliferation and invasion by downregulating AKT/mTOR signaling pathway in human melanoma cells.
Zhao G; Han X; Zheng S; Li Z; Sha Y; Ni J; Sun Z; Qiao S; Song Z
Oncol Rep; 2016 Feb; 35(2):1065-74. PubMed ID: 26573768
[TBL] [Abstract][Full Text] [Related]
32. Synergistic roles of p53 and HIF1α in human renal cell carcinoma-cell apoptosis responding to the inhibition of mTOR and MDM2 signaling pathways.
Liu QJ; Shen HL; Lin J; Xu XH; Ji ZG; Han X; Shang DH; Yang PQ
Drug Des Devel Ther; 2016; 10():745-55. PubMed ID: 26937175
[TBL] [Abstract][Full Text] [Related]
33. p53 regulates Stat3 phosphorylation and DNA binding activity in human prostate cancer cells expressing constitutively active Stat3.
Lin J; Tang H; Jin X; Jia G; Hsieh JT
Oncogene; 2002 May; 21(19):3082-8. PubMed ID: 12082540
[TBL] [Abstract][Full Text] [Related]
34. Cooperation of Musashi-2, Numb, MDM2, and P53 in drug resistance and malignant biology of pancreatic cancer.
Sheng W; Dong M; Chen C; Wang Z; Li Y; Wang K; Li Y; Zhou J
FASEB J; 2017 Jun; 31(6):2429-2438. PubMed ID: 28223335
[TBL] [Abstract][Full Text] [Related]
35. Phospholipase D elevates the level of MDM2 and suppresses DNA damage-induced increases in p53.
Hui L; Abbas T; Pielak RM; Joseph T; Bargonetti J; Foster DA
Mol Cell Biol; 2004 Jul; 24(13):5677-86. PubMed ID: 15199126
[TBL] [Abstract][Full Text] [Related]
36. Platycodin D induces tumor growth arrest by activating FOXO3a expression in prostate cancer in vitro and in vivo.
Zhou R; Lu Z; Liu K; Guo J; Liu J; Zhou Y; Yang J; Mi M; Xu H
Curr Cancer Drug Targets; 2015; 14(9):860-71. PubMed ID: 25431082
[TBL] [Abstract][Full Text] [Related]
37. Inhibiting NFAT1 for breast cancer therapy: New insights into the mechanism of action of MDM2 inhibitor JapA.
Qin JJ; Wang W; Voruganti S; Wang H; Zhang WD; Zhang R
Oncotarget; 2015 Oct; 6(32):33106-19. PubMed ID: 26461225
[TBL] [Abstract][Full Text] [Related]
38. PP2A mediates diosmin p53 activation to block HA22T cell proliferation and tumor growth in xenografted nude mice through PI3K-Akt-MDM2 signaling suppression.
Dung TD; Day CH; Binh TV; Lin CH; Hsu HH; Su CC; Lin YM; Tsai FJ; Kuo WW; Chen LM; Huang CY
Food Chem Toxicol; 2012 May; 50(5):1802-10. PubMed ID: 22289577
[TBL] [Abstract][Full Text] [Related]
39. Dual inhibition of nuclear factor kappa-B and Mdm2 enhance the antitumor effect of radiation therapy for pancreatic cancer.
Shirai Y; Shiba H; Iwase R; Haruki K; Fujiwara Y; Furukawa K; Uwagawa T; Ohashi T; Yanaga K
Cancer Lett; 2016 Jan; 370(2):177-84. PubMed ID: 26546875
[TBL] [Abstract][Full Text] [Related]
40. p53-independent activation of the hdm2-P2 promoter through multiple transcription factor response elements results in elevated hdm2 expression in estrogen receptor alpha-positive breast cancer cells.
Phelps M; Darley M; Primrose JN; Blaydes JP
Cancer Res; 2003 May; 63(10):2616-23. PubMed ID: 12750288
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
