496 related articles for article (PubMed ID: 17332349)
1. Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers.
Feldmann G; Dhara S; Fendrich V; Bedja D; Beaty R; Mullendore M; Karikari C; Alvarez H; Iacobuzio-Donahue C; Jimeno A; Gabrielson KL; Matsui W; Maitra A
Cancer Res; 2007 Mar; 67(5):2187-96. PubMed ID: 17332349
[TBL] [Abstract][Full Text] [Related]
2. Combination of hedgehog signaling blockage and chemotherapy leads to tumor reduction in pancreatic adenocarcinomas.
Bahra M; Kamphues C; Boas-Knoop S; Lippert S; Esendik U; Schüller U; Hartmann W; Waha A; Neuhaus P; Heppner F; Pietsch T; Koch A
Pancreas; 2012 Mar; 41(2):222-9. PubMed ID: 22076568
[TBL] [Abstract][Full Text] [Related]
3. An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer.
Feldmann G; Fendrich V; McGovern K; Bedja D; Bisht S; Alvarez H; Koorstra JB; Habbe N; Karikari C; Mullendore M; Gabrielson KL; Sharma R; Matsui W; Maitra A
Mol Cancer Ther; 2008 Sep; 7(9):2725-35. PubMed ID: 18790753
[TBL] [Abstract][Full Text] [Related]
4. Cyclopamine reverts acquired chemoresistance and down-regulates cancer stem cell markers in pancreatic cancer cell lines.
Yao J; An Y; Wie JS; Ji ZL; Lu ZP; Wu JL; Jiang KR; Chen P; Xu ZK; Miao Y
Swiss Med Wkly; 2011; 141():w13208. PubMed ID: 21630164
[TBL] [Abstract][Full Text] [Related]
5. Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancer.
Feldmann G; Habbe N; Dhara S; Bisht S; Alvarez H; Fendrich V; Beaty R; Mullendore M; Karikari C; Bardeesy N; Ouellette MM; Yu W; Maitra A
Gut; 2008 Oct; 57(10):1420-30. PubMed ID: 18515410
[TBL] [Abstract][Full Text] [Related]
6. Hedgehog inhibitor decreases chemosensitivity to 5-fluorouracil and gemcitabine under hypoxic conditions in pancreatic cancer.
Onishi H; Morifuji Y; Kai M; Suyama K; Iwasaki H; Katano M
Cancer Sci; 2012 Jul; 103(7):1272-9. PubMed ID: 22486854
[TBL] [Abstract][Full Text] [Related]
7. Cyclopamine increases the cytotoxic effects of paclitaxel and radiation but not cisplatin and gemcitabine in Hedgehog expressing pancreatic cancer cells.
Shafaee Z; Schmidt H; Du W; Posner M; Weichselbaum R
Cancer Chemother Pharmacol; 2006 Dec; 58(6):765-70. PubMed ID: 16552573
[TBL] [Abstract][Full Text] [Related]
8. Combined targeted treatment to eliminate tumorigenic cancer stem cells in human pancreatic cancer.
Mueller MT; Hermann PC; Witthauer J; Rubio-Viqueira B; Leicht SF; Huber S; Ellwart JW; Mustafa M; Bartenstein P; D'Haese JG; Schoenberg MH; Berger F; Jauch KW; Hidalgo M; Heeschen C
Gastroenterology; 2009 Sep; 137(3):1102-13. PubMed ID: 19501590
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer.
Olive KP; Jacobetz MA; Davidson CJ; Gopinathan A; McIntyre D; Honess D; Madhu B; Goldgraben MA; Caldwell ME; Allard D; Frese KK; Denicola G; Feig C; Combs C; Winter SP; Ireland-Zecchini H; Reichelt S; Howat WJ; Chang A; Dhara M; Wang L; Rückert F; Grützmann R; Pilarsky C; Izeradjene K; Hingorani SR; Huang P; Davies SE; Plunkett W; Egorin M; Hruban RH; Whitebread N; McGovern K; Adams J; Iacobuzio-Donahue C; Griffiths J; Tuveson DA
Science; 2009 Jun; 324(5933):1457-61. PubMed ID: 19460966
[TBL] [Abstract][Full Text] [Related]
10. Combining hedgehog signaling inhibition with focal irradiation on reduction of pancreatic cancer metastasis.
Gu D; Liu H; Su GH; Zhang X; Chin-Sinex H; Hanenberg H; Mendonca MS; Shannon HE; Chiorean EG; Xie J
Mol Cancer Ther; 2013 Jun; 12(6):1038-48. PubMed ID: 23468532
[TBL] [Abstract][Full Text] [Related]
11. Notch signaling pathway targeted therapy suppresses tumor progression and metastatic spread in pancreatic cancer.
Yabuuchi S; Pai SG; Campbell NR; de Wilde RF; De Oliveira E; Korangath P; Streppel MM; Rasheed ZA; Hidalgo M; Maitra A; Rajeshkumar NV
Cancer Lett; 2013 Jul; 335(1):41-51. PubMed ID: 23402814
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of the Hedgehog pathway induces autophagy in pancreatic ductal adenocarcinoma cells.
Xu Y; An Y; Wang X; Zha W; Li X
Oncol Rep; 2014 Feb; 31(2):707-12. PubMed ID: 24297612
[TBL] [Abstract][Full Text] [Related]
13. Metronomic gemcitabine in combination with sunitinib inhibits multisite metastasis and increases survival in an orthotopic model of pancreatic cancer.
Tran Cao HS; Bouvet M; Kaushal S; Keleman A; Romney E; Kim G; Fruehauf J; Imagawa DK; Hoffman RM; Katz MH
Mol Cancer Ther; 2010 Jul; 9(7):2068-78. PubMed ID: 20606044
[TBL] [Abstract][Full Text] [Related]
14. Gli3 mediates cell survival and sensitivity to cyclopamine in pancreatic cancer.
Steg A; Amm HM; Novak Z; Frost AR; Johnson MR
Cancer Biol Ther; 2010 Nov; 10(9):893-902. PubMed ID: 20814245
[TBL] [Abstract][Full Text] [Related]
15. Blockade of hedgehog signaling pathway as a therapeutic strategy for pancreatic cancer.
Xu FG; Ma QY; Wang Z
Cancer Lett; 2009 Oct; 283(2):119-24. PubMed ID: 19232458
[TBL] [Abstract][Full Text] [Related]
16. Hedgehog promotes neovascularization in pancreatic cancers by regulating Ang-1 and IGF-1 expression in bone-marrow derived pro-angiogenic cells.
Nakamura K; Sasajima J; Mizukami Y; Sugiyama Y; Yamazaki M; Fujii R; Kawamoto T; Koizumi K; Sato K; Fujiya M; Sasaki K; Tanno S; Okumura T; Shimizu N; Kawabe J; Karasaki H; Kono T; Ii M; Bardeesy N; Chung DC; Kohgo Y
PLoS One; 2010 Jan; 5(1):e8824. PubMed ID: 20098680
[TBL] [Abstract][Full Text] [Related]
17. Coadministration of Polymeric Conjugates of Docetaxel and Cyclopamine Synergistically Inhibits Orthotopic Pancreatic Cancer Growth and Metastasis.
Almawash SA; Mondal G; Mahato RI
Pharm Res; 2018 Jan; 35(1):17. PubMed ID: 29305793
[TBL] [Abstract][Full Text] [Related]
18. Gemcitabine enhances cell invasion via activating HAb18G/CD147-EGFR-pSTAT3 signaling.
Xu BQ; Fu ZG; Meng Y; Wu XQ; Wu B; Xu L; Jiang JL; Li L; Chen ZN
Oncotarget; 2016 Sep; 7(38):62177-62193. PubMed ID: 27556697
[TBL] [Abstract][Full Text] [Related]
19. Targeting cMET with INC280 impairs tumour growth and improves efficacy of gemcitabine in a pancreatic cancer model.
Brandes F; Schmidt K; Wagner C; Redekopf J; Schlitt HJ; Geissler EK; Lang SA
BMC Cancer; 2015 Feb; 15():71. PubMed ID: 25884642
[TBL] [Abstract][Full Text] [Related]
20. Molecular evidence for increased antitumor activity of gemcitabine by genistein in vitro and in vivo using an orthotopic model of pancreatic cancer.
Banerjee S; Zhang Y; Ali S; Bhuiyan M; Wang Z; Chiao PJ; Philip PA; Abbruzzese J; Sarkar FH
Cancer Res; 2005 Oct; 65(19):9064-72. PubMed ID: 16204081
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
