These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

317 related articles for article (PubMed ID: 17334390)

  • 1. Akt inhibitor A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition.
    Han EK; Leverson JD; McGonigal T; Shah OJ; Woods KW; Hunter T; Giranda VL; Luo Y
    Oncogene; 2007 Aug; 26(38):5655-61. PubMed ID: 17334390
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chronic inhibition of the mTORC1/S6K1 pathway increases insulin-induced PI3K activity but inhibits Akt2 and glucose transport stimulation in 3T3-L1 adipocytes.
    Veilleux A; Houde VP; Bellmann K; Marette A
    Mol Endocrinol; 2010 Apr; 24(4):766-78. PubMed ID: 20203102
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition.
    Breuleux M; Klopfenstein M; Stephan C; Doughty CA; Barys L; Maira SM; Kwiatkowski D; Lane HA
    Mol Cancer Ther; 2009 Apr; 8(4):742-53. PubMed ID: 19372546
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility.
    Gulati N; Karsy M; Albert L; Murali R; Jhanwar-Uniyal M
    Int J Oncol; 2009 Oct; 35(4):731-40. PubMed ID: 19724909
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Longitudinal inhibition of PI3K/Akt/mTOR signaling by LY294002 and rapamycin induces growth arrest of adult T-cell leukemia cells.
    Ikezoe T; Nishioka C; Bandobashi K; Yang Y; Kuwayama Y; Adachi Y; Takeuchi T; Koeffler HP; Taguchi H
    Leuk Res; 2007 May; 31(5):673-82. PubMed ID: 17007924
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Class I PI3-kinase or Akt inhibition do not impair axonal polarization, but slow down axonal elongation.
    Diez H; Benitez MJ; Fernandez S; Torres-Aleman I; Garrido JJ; Wandosell F
    Biochim Biophys Acta; 2016 Nov; 1863(11):2574-2583. PubMed ID: 27421985
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dual PI3K/mTOR Inhibitors Induce Rapid Overactivation of the MEK/ERK Pathway in Human Pancreatic Cancer Cells through Suppression of mTORC2.
    Soares HP; Ming M; Mellon M; Young SH; Han L; Sinnet-Smith J; Rozengurt E
    Mol Cancer Ther; 2015 Apr; 14(4):1014-23. PubMed ID: 25673820
    [TBL] [Abstract][Full Text] [Related]  

  • 8. mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling.
    Julien LA; Carriere A; Moreau J; Roux PP
    Mol Cell Biol; 2010 Feb; 30(4):908-21. PubMed ID: 19995915
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Serine 302 Phosphorylation of Mouse Insulin Receptor Substrate 1 (IRS1) Is Dispensable for Normal Insulin Signaling and Feedback Regulation by Hepatic S6 Kinase.
    Copps KD; Hançer NJ; Qiu W; White MF
    J Biol Chem; 2016 Apr; 291(16):8602-17. PubMed ID: 26846849
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.
    Ozes ON; Akca H; Mayo LD; Gustin JA; Maehama T; Dixon JE; Donner DB
    Proc Natl Acad Sci U S A; 2001 Apr; 98(8):4640-5. PubMed ID: 11287630
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.
    Guertin DA; Stevens DM; Thoreen CC; Burds AA; Kalaany NY; Moffat J; Brown M; Fitzgerald KJ; Sabatini DM
    Dev Cell; 2006 Dec; 11(6):859-71. PubMed ID: 17141160
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Serotonin-induced growth of pulmonary artery smooth muscle requires activation of phosphatidylinositol 3-kinase/serine-threonine protein kinase B/mammalian target of rapamycin/p70 ribosomal S6 kinase 1.
    Liu Y; Fanburg BL
    Am J Respir Cell Mol Biol; 2006 Feb; 34(2):182-91. PubMed ID: 16195541
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Upregulation of mTORC2 activation by the selective agonist of EPAC, 8-CPT-2Me-cAMP, in prostate cancer cells: assembly of a multiprotein signaling complex.
    Misra UK; Pizzo SV
    J Cell Biochem; 2012 May; 113(5):1488-500. PubMed ID: 22173835
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rapamycin regulates the phosphorylation of rictor.
    Akcakanat A; Singh G; Hung MC; Meric-Bernstam F
    Biochem Biophys Res Commun; 2007 Oct; 362(2):330-3. PubMed ID: 17707343
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hypoxia-induced endothelial proliferation requires both mTORC1 and mTORC2.
    Li W; Petrimpol M; Molle KD; Hall MN; Battegay EJ; Humar R
    Circ Res; 2007 Jan; 100(1):79-87. PubMed ID: 17110594
    [TBL] [Abstract][Full Text] [Related]  

  • 16. RAD 001 (everolimus) prevents mTOR and Akt late re-activation in response to imatinib in chronic myeloid leukemia.
    Mancini M; Petta S; Martinelli G; Barbieri E; Santucci MA
    J Cell Biochem; 2010 Feb; 109(2):320-8. PubMed ID: 20014066
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of Akt (ser473) phosphorylation and rapamycin-resistant cell growth by knockdown of mammalian target of rapamycin with small interfering RNA in vascular endothelial growth factor receptor-1-targeting vector.
    Koide H; Asai T; Furuya K; Tsuzuku T; Kato H; Dewa T; Nango M; Maeda N; Oku N
    Biol Pharm Bull; 2011; 34(5):602-8. PubMed ID: 21532145
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Raptor-rictor axis in TGFbeta-induced protein synthesis.
    Das F; Ghosh-Choudhury N; Mahimainathan L; Venkatesan B; Feliers D; Riley DJ; Kasinath BS; Choudhury GG
    Cell Signal; 2008 Feb; 20(2):409-23. PubMed ID: 18068336
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.
    Marzec M; Kasprzycka M; Liu X; El-Salem M; Halasa K; Raghunath PN; Bucki R; Wlodarski P; Wasik MA
    Oncogene; 2007 Aug; 26(38):5606-14. PubMed ID: 17353907
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Akt-dependent activation of mTORC1 complex involves phosphorylation of mTOR (mammalian target of rapamycin) by IκB kinase α (IKKα).
    Dan HC; Ebbs A; Pasparakis M; Van Dyke T; Basseres DS; Baldwin AS
    J Biol Chem; 2014 Sep; 289(36):25227-40. PubMed ID: 24990947
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.