These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 17337132)

  • 1. Intact Mre11/Rad50/Nbs1 complex predicts good response to radiotherapy in early breast cancer.
    Söderlund K; Stål O; Skoog L; Rutqvist LE; Nordenskjöld B; Askmalm MS
    Int J Radiat Oncol Biol Phys; 2007 May; 68(1):50-8. PubMed ID: 17337132
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.
    Lee JH; Mand MR; Deshpande RA; Kinoshita E; Yang SH; Wyman C; Paull TT
    J Biol Chem; 2013 May; 288(18):12840-51. PubMed ID: 23525106
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Mre11/Rad50/Nbs1 complex and its role as a DNA double-strand break sensor for ATM.
    Paull TT; Lee JH
    Cell Cycle; 2005 Jun; 4(6):737-40. PubMed ID: 15908798
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.
    Williams RS; Williams JS; Tainer JA
    Biochem Cell Biol; 2007 Aug; 85(4):509-20. PubMed ID: 17713585
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Independent roles for nibrin and Mre11-Rad50 in the activation and function of Atm.
    Cerosaletti K; Concannon P
    J Biol Chem; 2004 Sep; 279(37):38813-9. PubMed ID: 15234984
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Purification and biochemical characterization of ataxia-telangiectasia mutated and Mre11/Rad50/Nbs1.
    Lee JH; Paull TT
    Methods Enzymol; 2006; 408():529-39. PubMed ID: 16793391
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex.
    Lee JH; Paull TT
    Science; 2005 Apr; 308(5721):551-4. PubMed ID: 15790808
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex.
    Dupré A; Boyer-Chatenet L; Gautier J
    Nat Struct Mol Biol; 2006 May; 13(5):451-7. PubMed ID: 16622404
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NBS1 is regulated by two kind of mechanisms: ATM-dependent complex formation with MRE11 and RAD50, and cell cycle-dependent degradation of protein.
    Zhou H; Kawamura K; Yanagihara H; Kobayashi J; Zhang-Akiyama QM
    J Radiat Res; 2017 Jul; 58(4):487-494. PubMed ID: 28369484
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex.
    Lee JH; Paull TT
    Science; 2004 Apr; 304(5667):93-6. PubMed ID: 15064416
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Breast cancer risk is associated with the genes encoding the DNA double-strand break repair Mre11/Rad50/Nbs1 complex.
    Hsu HM; Wang HC; Chen ST; Hsu GC; Shen CY; Yu JC
    Cancer Epidemiol Biomarkers Prev; 2007 Oct; 16(10):2024-32. PubMed ID: 17932350
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity.
    Jazayeri A; Balestrini A; Garner E; Haber JE; Costanzo V
    EMBO J; 2008 Jul; 27(14):1953-62. PubMed ID: 18596698
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 53BP1 promotes ATM activity through direct interactions with the MRN complex.
    Lee JH; Goodarzi AA; Jeggo PA; Paull TT
    EMBO J; 2010 Feb; 29(3):574-85. PubMed ID: 20010693
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression of ATM, p53, and the MRE11-Rad50-NBS1 complex in myoepithelial cells from benign and malignant proliferations of the breast.
    Angèle S; Jones C; Reis Filho JS; Fulford LG; Treilleux I; Lakhani SR; Hall J
    J Clin Pathol; 2004 Nov; 57(11):1179-84. PubMed ID: 15509680
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Overexpression of the MRE11-RAD50-NBS1 (MRN) complex in rectal cancer correlates with poor response to neoadjuvant radiotherapy and prognosis.
    Ho V; Chung L; Singh A; Lea V; Abubakar A; Lim SH; Ng W; Lee M; de Souza P; Shin JS; Lee CS
    BMC Cancer; 2018 Sep; 18(1):869. PubMed ID: 30176843
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lack of MRE11-RAD50-NBS1 (MRN) complex detection occurs frequently in low-grade epithelial ovarian cancer.
    Brandt S; Samartzis EP; Zimmermann AK; Fink D; Moch H; Noske A; Dedes KJ
    BMC Cancer; 2017 Jan; 17(1):44. PubMed ID: 28073364
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ATM, the Mre11/Rad50/Nbs1 complex, and topoisomerase I are concentrated in the nucleus of Purkinje neurons in the juvenile human brain.
    Gorodetsky E; Calkins S; Ahn J; Brooks PJ
    DNA Repair (Amst); 2007 Nov; 6(11):1698-707. PubMed ID: 17706468
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Mre11/Rad50/Nbs1 complex plays an important role in the prevention of DNA rereplication in mammalian cells.
    Lee AY; Liu E; Wu X
    J Biol Chem; 2007 Nov; 282(44):32243-55. PubMed ID: 17715134
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex.
    Stracker TH; Morales M; Couto SS; Hussein H; Petrini JH
    Nature; 2007 May; 447(7141):218-21. PubMed ID: 17429352
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation and regulation of ATM kinase activity in response to DNA double-strand breaks.
    Lee JH; Paull TT
    Oncogene; 2007 Dec; 26(56):7741-8. PubMed ID: 18066086
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.