BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

239 related articles for article (PubMed ID: 17339891)

  • 21. Prognostic value of tumoral thymidylate synthase and p53 in metastatic colorectal cancer patients receiving fluorouracil-based chemotherapy: phenotypic and genotypic analyses.
    Etienne MC; Chazal M; Laurent-Puig P; Magné N; Rosty C; Formento JL; Francoual M; Formento P; Renée N; Chamorey E; Bourgeon A; Seitz JF; Delpero JR; Letoublon C; Pezet D; Milano G
    J Clin Oncol; 2002 Jun; 20(12):2832-43. PubMed ID: 12065560
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in colorectal cancer and normal mucosa in patients.
    Amatori F; Di Paolo A; Del Tacca M; Fontanini G; Vannozzi F; Boldrini L; Bocci G; Lastella M; Danesi R
    Pharmacogenet Genomics; 2006 Nov; 16(11):809-16. PubMed ID: 17047489
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Pharmacogenomic dissection of resistance to thymidylate synthase inhibitors.
    Wang W; Marsh S; Cassidy J; McLeod HL
    Cancer Res; 2001 Jul; 61(14):5505-10. PubMed ID: 11454699
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Mechanisms of acquired resistance to thymidylate synthase inhibitors: the role of enzyme stability.
    Kitchens ME; Forsthoefel AM; Barbour KW; Spencer HT; Berger FG
    Mol Pharmacol; 1999 Nov; 56(5):1063-70. PubMed ID: 10531414
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines.
    van Triest B; Pinedo HM; van Hensbergen Y; Smid K; Telleman F; Schoenmakers PS; van der Wilt CL; van Laar JA; Noordhuis P; Jansen G; Peters GJ
    Clin Cancer Res; 1999 Mar; 5(3):643-54. PubMed ID: 10100718
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Thymidine kinase, thymidylate synthase, and dihydropyrimidine dehydrogenase profiles of cell lines of the National Cancer Institute's Anticancer Drug Screen.
    Grem JL; Danenberg KD; Behan K; Parr A; Young L; Danenberg PV; Nguyen D; Drake J; Monks A; Allegra CJ
    Clin Cancer Res; 2001 Apr; 7(4):999-1009. PubMed ID: 11309351
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Downstream molecular determinants of response to 5-fluorouracil and antifolate thymidylate synthase inhibitors.
    Van Triest B; Pinedo HM; Giaccone G; Peters GJ
    Ann Oncol; 2000 Apr; 11(4):385-91. PubMed ID: 10847455
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Thymidylate synthase pharmacogenetics in colorectal cancer.
    Marsh S; McLeod HL
    Clin Colorectal Cancer; 2001 Nov; 1(3):175-8; discussion 179-81. PubMed ID: 12450432
    [TBL] [Abstract][Full Text] [Related]  

  • 29. High pemetrexed sensitivity of docetaxel-resistant A549 cells is mediated by TP53 status and downregulated thymidylate synthase.
    Kuo WT; Tu DG; Chiu LY; Sheu GT; Wu MF
    Oncol Rep; 2017 Nov; 38(5):2787-2795. PubMed ID: 28901493
    [TBL] [Abstract][Full Text] [Related]  

  • 30. [Results of prophylactic hepatic arterial chemotherapy for liver metastases of Dukes C colorectal cancer--correlation with tumoral expression of dihydropyrimidine dehydrogenase, thymidylate synthase, p53, or orotate phosphoribosyl transferase].
    Ishida H; Yamada H; Shirakawa K; Nakada H; Ohsawa T; Takeuchi I; Okada N; Yokoyama M; Inokuma S; Suzuki T; Odaka A; Hoshino T; Murata N; Hashimoto D; Itoyama S; Mori T; Matsumoto Y; Miura T
    Gan To Kagaku Ryoho; 2003 Oct; 30(11):1621-6. PubMed ID: 14619479
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Drug-resistant variants of Escherichia coli thymidylate synthase: effects of substitutions at Pro-254.
    Fantz C; Shaw D; Jennings W; Forsthoefel A; Kitchens M; Phan J; Minor W; Lebioda L; Berger FG; Spencer HT
    Mol Pharmacol; 2000 Feb; 57(2):359-66. PubMed ID: 10648646
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Multi-level gene expression profiles affected by thymidylate synthase and 5-fluorouracil in colon cancer.
    Xi Y; Nakajima G; Schmitz JC; Chu E; Ju J
    BMC Genomics; 2006 Apr; 7():68. PubMed ID: 16584549
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The means to an end of tumor cell resistance to chemotherapeutic drugs targeting thymidylate synthase: shoot the messenger.
    Berg RW; Ferguso PJ; DeMoor JM; Vincen MD; Koropatnick J
    Curr Drug Targets; 2002 Aug; 3(4):297-309. PubMed ID: 12102601
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Oxaliplatin activity in selected and unselected human ovarian and colorectal cancer cell lines.
    Noordhuis P; Laan AC; van de Born K; Losekoot N; Kathmann I; Peters GJ
    Biochem Pharmacol; 2008 Jul; 76(1):53-61. PubMed ID: 18508032
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Dihydropyrimidine dehydrogenase but not thymidylate synthase expression is associated with resistance to 5-fluorouracil in colorectal cancer.
    Nita ME; Tominaga O; Nagawa H; Tsuruo T; Muto T
    Hepatogastroenterology; 1998; 45(24):2117-22. PubMed ID: 9951876
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Associations between polymorphisms in the thymidylate synthase gene, the expression of thymidylate synthase mRNA and the microsatellite instability phenotype of colorectal cancer.
    Merkelbach-Bruse S; Hans V; Mathiak M; Sanguedolce R; Alessandro R; Rüschoff J; Büttner R; Houshdaran F; Gullotti L
    Oncol Rep; 2004 Apr; 11(4):839-43. PubMed ID: 15010882
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Characterization of a thymidylate synthase (TS)-inducible cell line: a model system for studying sensitivity to TS- and non-TS-targeted chemotherapies.
    Longley DB; Ferguson PR; Boyer J; Latif T; Lynch M; Maxwell P; Harkin DP; Johnston PG
    Clin Cancer Res; 2001 Nov; 7(11):3533-9. PubMed ID: 11705873
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Thymidilate synthase and p53 primary tumour expression as predictive factors for advanced colorectal cancer patients.
    Paradiso A; Simone G; Petroni S; Leone B; Vallejo C; Lacava J; Romero A; Machiavelli M; De Lena M; Allegra CJ; Johnston PG
    Br J Cancer; 2000 Feb; 82(3):560-7. PubMed ID: 10682666
    [TBL] [Abstract][Full Text] [Related]  

  • 39. A novel approach to thymidylate synthase as a target for cancer chemotherapy.
    Li Q; Boyer C; Lee JY; Shepard HM
    Mol Pharmacol; 2001 Mar; 59(3):446-52. PubMed ID: 11179438
    [TBL] [Abstract][Full Text] [Related]  

  • 40. High thymidylate synthase expression in colorectal cancer with microsatellite instability: implications for chemotherapeutic strategies.
    Ricciardiello L; Ceccarelli C; Angiolini G; Pariali M; Chieco P; Paterini P; Biasco G; Martinelli GN; Roda E; Bazzoli F
    Clin Cancer Res; 2005 Jun; 11(11):4234-40. PubMed ID: 15930362
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.