139 related articles for article (PubMed ID: 17340656)
1. Virtual screening leads to the discovery of an effective antagonist of lymphocyte function-associated antigen-1.
Shoda M; Harada T; Yano K; Stahura FL; Himeno T; Shiojiri S; Kogami Y; Kouji H; Bajorath J
ChemMedChem; 2007 Apr; 2(4):515-21. PubMed ID: 17340656
[TBL] [Abstract][Full Text] [Related]
2. Generation of an LFA-1 antagonist by the transfer of the ICAM-1 immunoregulatory epitope to a small molecule.
Gadek TR; Burdick DJ; McDowell RS; Stanley MS; Marsters JC; Paris KJ; Oare DA; Reynolds ME; Ladner C; Zioncheck KA; Lee WP; Gribling P; Dennis MS; Skelton NJ; Tumas DB; Clark KR; Keating SM; Beresini MH; Tilley JW; Presta LG; Bodary SC
Science; 2002 Feb; 295(5557):1086-9. PubMed ID: 11834839
[TBL] [Abstract][Full Text] [Related]
3. Adhesion of peripheral blood mononuclear cells and CD4+ T cells from patients with psoriasis to cultured endothelial cells via the interaction between lymphocyte function-associated antigen type 1 and intercellular adhesion molecule 1.
Watabe D; Kanno H; Yoshida A; Kurose A; Akasaka T; Sawai T
Br J Dermatol; 2007 Aug; 157(2):259-65. PubMed ID: 17596165
[TBL] [Abstract][Full Text] [Related]
4. Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site.
Weitz-Schmidt G; Welzenbach K; Brinkmann V; Kamata T; Kallen J; Bruns C; Cottens S; Takada Y; Hommel U
Nat Med; 2001 Jun; 7(6):687-92. PubMed ID: 11385505
[TBL] [Abstract][Full Text] [Related]
5. Cell-free ligand-binding assays for integrin LFA-1.
Yuki K
Methods Mol Biol; 2012; 757():73-8. PubMed ID: 21909907
[TBL] [Abstract][Full Text] [Related]
6. Characterization of molecular interactions between intercellular adhesion molecule-1 and leukocyte function- associated antigen-1.
Woska JR; Morelock MM; Jeanfavre DD; Bormann BJ
J Immunol; 1996 Jun; 156(12):4680-5. PubMed ID: 8648112
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of ICAM-1/LFA-1-mediated heterotypic T-cell adhesion to epithelial cells: design of ICAM-1 cyclic peptides.
Anderson ME; Yakovleva T; Hu Y; Siahaan TJ
Bioorg Med Chem Lett; 2004 Mar; 14(6):1399-402. PubMed ID: 15006370
[TBL] [Abstract][Full Text] [Related]
8. Tetramethylpyrazine inhibits phytohemagglutinin-induced upregulation of ICAM-1 and LFA-1 mediated leukocyte adhesion.
Zhao H; Zhu C; Li X; Dong X; Zhuang F; Wang X; Stoltz JF
Clin Hemorheol Microcirc; 2000; 23(2-4):145-51. PubMed ID: 11321434
[TBL] [Abstract][Full Text] [Related]
9. Statin-derived 1,3-oxazinan-2-ones as submicromolar inhibitors of LFA-1/ICAM-1 interaction: stabilization of the metabolically labile vanillyl side chain.
Ullrich T; Baumann K; Welzenbach K; Schmutz S; Camenisch G; Meingassner JG; Weitz-Schmidt G
Bioorg Med Chem Lett; 2004 May; 14(10):2483-7. PubMed ID: 15109637
[TBL] [Abstract][Full Text] [Related]
10. Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain.
Kallen J; Welzenbach K; Ramage P; Geyl D; Kriwacki R; Legge G; Cottens S; Weitz-Schmidt G; Hommel U
J Mol Biol; 1999 Sep; 292(1):1-9. PubMed ID: 10493852
[TBL] [Abstract][Full Text] [Related]
11. Dynamic control of allosteric antagonism of leukocyte function antigen-1 and intercellular adhesion molecule-1 interaction.
Nam K; Maiorov V; Feuston B; Kearsley S
Proteins; 2006 Aug; 64(2):376-84. PubMed ID: 16705652
[TBL] [Abstract][Full Text] [Related]
12. Model of the alphaLbeta2 integrin I-domain/ICAM-1 DI interface suggests that subtle changes in loop orientation determine ligand specificity.
Legge GB; Morris GM; Sanner MF; Takada Y; Olson AJ; Grynszpan F
Proteins; 2002 Aug; 48(2):151-60. PubMed ID: 12112684
[TBL] [Abstract][Full Text] [Related]
13. Structure of an allosteric inhibitor of LFA-1 bound to the I-domain studied by crystallography, NMR, and calorimetry.
Crump MP; Ceska TA; Spyracopoulos L; Henry A; Archibald SC; Alexander R; Taylor RJ; Findlow SC; O'Connell J; Robinson MK; Shock A
Biochemistry; 2004 Mar; 43(9):2394-404. PubMed ID: 14992576
[TBL] [Abstract][Full Text] [Related]
14. Direct quantification of the modulation of interaction between cell- or surface-bound LFA-1 and ICAM-1.
Vitte J; Pierres A; Benoliel AM; Bongrand P
J Leukoc Biol; 2004 Sep; 76(3):594-602. PubMed ID: 15240749
[TBL] [Abstract][Full Text] [Related]
15. Sequence recognition of alpha-LFA-1-derived peptides by ICAM-1 cell receptors: inhibitors of T-cell adhesion.
Yusuf-Makagiansar H; Yakovleva TV; Tejo BA; Jones K; Hu Y; Verkhivker GM; Audus KL; Siahaan TJ
Chem Biol Drug Des; 2007 Sep; 70(3):237-46. PubMed ID: 17718718
[TBL] [Abstract][Full Text] [Related]
16. Statin compounds reduce human immunodeficiency virus type 1 replication by preventing the interaction between virion-associated host intercellular adhesion molecule 1 and its natural cell surface ligand LFA-1.
Giguère JF; Tremblay MJ
J Virol; 2004 Nov; 78(21):12062-5. PubMed ID: 15479847
[TBL] [Abstract][Full Text] [Related]
17. Cutting edge: a small molecule antagonist of LFA-1-mediated cell adhesion.
Kelly TA; Jeanfavre DD; McNeil DW; Woska JR; Reilly PL; Mainolfi EA; Kishimoto KM; Nabozny GH; Zinter R; Bormann BJ; Rothlein R
J Immunol; 1999 Nov; 163(10):5173-7. PubMed ID: 10553036
[TBL] [Abstract][Full Text] [Related]
18. Discovery and development of 5-[(5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non-7-yl-methyl]-3-thiophenecarboxylic acid (BMS-587101)--a small molecule antagonist of leukocyte function associated antigen-1.
Potin D; Launay M; Monatlik F; Malabre P; Fabreguettes M; Fouquet A; Maillet M; Nicolai E; Dorgeret L; Chevallier F; Besse D; Dufort M; Caussade F; Ahmad SZ; Stetsko DK; Skala S; Davis PM; Balimane P; Patel K; Yang Z; Marathe P; Postelneck J; Townsend RM; Goldfarb V; Sheriff S; Einspahr H; Kish K; Malley MF; DiMarco JD; Gougoutas JZ; Kadiyala P; Cheney DL; Tejwani RW; Murphy DK; Mcintyre KW; Yang X; Chao S; Leith L; Xiao Z; Mathur A; Chen BC; Wu DR; Traeger SC; McKinnon M; Barrish JC; Robl JA; Iwanowicz EJ; Suchard SJ; Dhar TG
J Med Chem; 2006 Nov; 49(24):6946-9. PubMed ID: 17125246
[TBL] [Abstract][Full Text] [Related]
19. The pharmacologic assessment of a novel lymphocyte function-associated antigen-1 antagonist (SAR 1118) for the treatment of keratoconjunctivitis sicca in dogs.
Murphy CJ; Bentley E; Miller PE; McIntyre K; Leatherberry G; Dubielzig R; Giuliano E; Moore CP; Phillips TE; Smith PB; Prescott E; Miller JM; Thomas P; Scagliotti R; Esson D; Gadek T; O'Neill CA
Invest Ophthalmol Vis Sci; 2011 May; 52(6):3174-80. PubMed ID: 21330663
[TBL] [Abstract][Full Text] [Related]
20. Locking a leukocyte integrin with statins.
Frenette PS
N Engl J Med; 2001 Nov; 345(19):1419-21. PubMed ID: 11794177
[No Abstract] [Full Text] [Related]
[Next] [New Search]
