BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 17341491)

  • 1. Production of lysophosphatidylcholine by cPLA2 in the brain of mice lacking PPT1 is a signal for phagocyte infiltration.
    Zhang Z; Lee YC; Kim SJ; Choi MS; Tsai PC; Saha A; Wei H; Xu Y; Xiao YJ; Zhang P; Heffer A; Mukherjee AB
    Hum Mol Genet; 2007 Apr; 16(7):837-47. PubMed ID: 17341491
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Palmitoyl-protein thioesterase-1 deficiency mediates the activation of the unfolded protein response and neuronal apoptosis in INCL.
    Zhang Z; Lee YC; Kim SJ; Choi MS; Tsai PC; Xu Y; Xiao YJ; Zhang P; Heffer A; Mukherjee AB
    Hum Mol Genet; 2006 Jan; 15(2):337-46. PubMed ID: 16368712
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Palmitoyl-protein thioesterase-1 deficiency leads to the activation of caspase-9 and contributes to rapid neurodegeneration in INCL.
    Kim SJ; Zhang Z; Lee YC; Mukherjee AB
    Hum Mol Genet; 2006 May; 15(10):1580-6. PubMed ID: 16571600
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Endoplasmic reticulum stress-induced caspase-4 activation mediates apoptosis and neurodegeneration in INCL.
    Kim SJ; Zhang Z; Hitomi E; Lee YC; Mukherjee AB
    Hum Mol Genet; 2006 Jun; 15(11):1826-34. PubMed ID: 16644870
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ppt1-deficiency dysregulates lysosomal Ca
    Mondal A; Appu AP; Sadhukhan T; Bagh MB; Previde RM; Sadhukhan S; Stojilkovic S; Liu A; Mukherjee AB
    J Inherit Metab Dis; 2022 May; 45(3):635-656. PubMed ID: 35150145
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cln3-mutations underlying juvenile neuronal ceroid lipofuscinosis cause significantly reduced levels of Palmitoyl-protein thioesterases-1 (Ppt1)-protein and Ppt1-enzyme activity in the lysosome.
    Appu AP; Bagh MB; Sadhukhan T; Mondal A; Casey S; Mukherjee AB
    J Inherit Metab Dis; 2019 Sep; 42(5):944-954. PubMed ID: 31025705
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cln1 gene disruption in mice reveals a common pathogenic link between two of the most lethal childhood neurodegenerative lysosomal storage disorders.
    Chandra G; Bagh MB; Peng S; Saha A; Sarkar C; Moralle M; Zhang Z; Mukherjee AB
    Hum Mol Genet; 2015 Oct; 24(19):5416-32. PubMed ID: 26160911
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cln1-mutations suppress Rab7-RILP interaction and impair autophagy contributing to neuropathology in a mouse model of infantile neuronal ceroid lipofuscinosis.
    Sarkar C; Sadhukhan T; Bagh MB; Appu AP; Chandra G; Mondal A; Saha A; Mukherjee AB
    J Inherit Metab Dis; 2020 Sep; 43(5):1082-1101. PubMed ID: 32279353
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The blood-brain barrier is disrupted in a mouse model of infantile neuronal ceroid lipofuscinosis: amelioration by resveratrol.
    Saha A; Sarkar C; Singh SP; Zhang Z; Munasinghe J; Peng S; Chandra G; Kong E; Mukherjee AB
    Hum Mol Genet; 2012 May; 21(10):2233-44. PubMed ID: 22331300
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Disruption of adaptive energy metabolism and elevated ribosomal p-S6K1 levels contribute to INCL pathogenesis: partial rescue by resveratrol.
    Wei H; Zhang Z; Saha A; Peng S; Chandra G; Quezado Z; Mukherjee AB
    Hum Mol Genet; 2011 Mar; 20(6):1111-21. PubMed ID: 21224254
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Neuroprotection and lifespan extension in Ppt1(-/-) mice by NtBuHA: therapeutic implications for INCL.
    Sarkar C; Chandra G; Peng S; Zhang Z; Liu A; Mukherjee AB
    Nat Neurosci; 2013 Nov; 16(11):1608-17. PubMed ID: 24056696
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Palmitoyl protein thioesterase-1 deficiency impairs synaptic vesicle recycling at nerve terminals, contributing to neuropathology in humans and mice.
    Kim SJ; Zhang Z; Sarkar C; Tsai PC; Lee YC; Dye L; Mukherjee AB
    J Clin Invest; 2008 Sep; 118(9):3075-86. PubMed ID: 18704195
    [TBL] [Abstract][Full Text] [Related]  

  • 13. AAV2-mediated ocular gene therapy for infantile neuronal ceroid lipofuscinosis.
    Griffey M; Macauley SL; Ogilvie JM; Sands MS
    Mol Ther; 2005 Sep; 12(3):413-21. PubMed ID: 15979943
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Deficiency of the INCL protein Ppt1 results in changes in ectopic F1-ATP synthase and altered cholesterol metabolism.
    Lyly A; Marjavaara SK; Kyttälä A; Uusi-Rauva K; Luiro K; Kopra O; Martinez LO; Tanhuanpää K; Kalkkinen N; Suomalainen A; Jauhiainen M; Jalanko A
    Hum Mol Genet; 2008 May; 17(10):1406-17. PubMed ID: 18245779
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Compromised astrocyte function and survival negatively impact neurons in infantile neuronal ceroid lipofuscinosis.
    Lange J; Haslett LJ; Lloyd-Evans E; Pocock JM; Sands MS; Williams BP; Cooper JD
    Acta Neuropathol Commun; 2018 Aug; 6(1):74. PubMed ID: 30089511
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The role of attenuated astrocyte activation in infantile neuronal ceroid lipofuscinosis.
    Macauley SL; Pekny M; Sands MS
    J Neurosci; 2011 Oct; 31(43):15575-85. PubMed ID: 22031903
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice.
    Gupta P; Soyombo AA; Atashband A; Wisniewski KE; Shelton JM; Richardson JA; Hammer RE; Hofmann SL
    Proc Natl Acad Sci U S A; 2001 Nov; 98(24):13566-71. PubMed ID: 11717424
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Palmitoyl protein thioesterase 1 (PPT1) deficiency causes endocytic defects connected to abnormal saposin processing.
    Ahtiainen L; Luiro K; Kauppi M; Tyynelä J; Kopra O; Jalanko A
    Exp Cell Res; 2006 May; 312(9):1540-53. PubMed ID: 16542649
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Histochemical localization of palmitoyl protein thioesterase-1 activity.
    Dearborn JT; Ramachandran S; Shyng C; Lu JY; Thornton J; Hofmann SL; Sands MS
    Mol Genet Metab; 2016 Feb; 117(2):210-6. PubMed ID: 26597320
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluation of neurodegeneration in a mouse model of infantile batten disease by magnetic resonance imaging and magnetic resonance spectroscopy.
    Munasinghe J; Zhang Z; Kong E; Heffer A; Mukherjee AB
    Neurodegener Dis; 2012; 9(4):159-69. PubMed ID: 22327870
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.