BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

227 related articles for article (PubMed ID: 17345084)

  • 1. Murine toxicology and pharmacokinetics of novel retinoic acid metabolism blocking agents.
    Patel JB; Khandelwal A; Chopra P; Handratta VD; Njar VC
    Cancer Chemother Pharmacol; 2007 Nov; 60(6):899-905. PubMed ID: 17345084
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Murine toxicology and pharmacokinetics evaluation of retinoic acid metabolism blocking agent (RAMBA), VN/12-1.
    Godbole AM; Purushottamachar P; Martin MS; Njar VC
    Cancer Chemother Pharmacol; 2012 Aug; 70(2):339-44. PubMed ID: 22580781
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Quantification of a novel retinoic acid metabolism inhibitor, 4-(1H-imidazol-1-yl)retinoic acid (VN/14-1RA) and other retinoids in rat plasma by liquid chromatography with diode-array detection.
    Wu C; Njar V; Brodie A; Borenstein M; Nnane I
    J Chromatogr B Analyt Technol Biomed Life Sci; 2004 Oct; 810(2):203-8. PubMed ID: 15380716
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel retinoic acid metabolism blocking agents have potent inhibitory activities on human breast cancer cells and tumour growth.
    Patel JB; Mehta J; Belosay A; Sabnis G; Khandelwal A; Brodie AM; Soprano DR; Njar VC
    Br J Cancer; 2007 Apr; 96(8):1204-15. PubMed ID: 17387344
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacokinetics of novel inhibitors of androgen synthesis after intravenous administration in mice.
    Nnane IP; Njar VC; Brodie AM
    Cancer Chemother Pharmacol; 2003 Jun; 51(6):519-24. PubMed ID: 12715204
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pharmacology of all-trans-retinoic acid in children with acute promyelocytic leukemia.
    Lanvers C; Reinhardt D; Dübbers A; Wagner-Bohn A; Creutzig U; Ritter J; Boos J
    Med Pediatr Oncol; 2003 May; 40(5):293-301. PubMed ID: 12652617
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibitory effects of retinoic acid metabolism blocking agents (RAMBAs) on the growth of human prostate cancer cells and LNCaP prostate tumour xenografts in SCID mice.
    Huynh CK; Brodie AM; Njar VC
    Br J Cancer; 2006 Feb; 94(4):513-23. PubMed ID: 16449997
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacokinetics of intravenously administered liposomal all-trans-retinoic acid (ATRA) and orally administered ATRA in healthy volunteers.
    Ozpolat B; Lopez-Berestein G; Adamson P; Fu CJ; Williams AH
    J Pharm Pharm Sci; 2003; 6(2):292-301. PubMed ID: 12935441
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacokinetics of all-trans retinoic acid, 13-cis retinoic acid, and fenretinide in plasma and brain of Rat.
    Le Doze F; Debruyne D; Albessard F; Barre L; Defer GL
    Drug Metab Dispos; 2000 Feb; 28(2):205-8. PubMed ID: 10640519
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel retinoic acid metabolism blocking agents endowed with multiple biological activities are efficient growth inhibitors of human breast and prostate cancer cells in vitro and a human breast tumor xenograft in nude mice.
    Patel JB; Huynh CK; Handratta VD; Gediya LK; Brodie AM; Goloubeva OG; Clement OO; Nanne IP; Soprano DR; Njar VC
    J Med Chem; 2004 Dec; 47(27):6716-29. PubMed ID: 15615521
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacokinetics of 9-methoxy-N,N-dimethyl-5-nitropyrazolo [3,4, 5-kl]acridine-2(6H)-propanamine (PZA, PD 115934, NSC 366140) in mice: guidelines for early clinical trials1.
    Foster BJ; Wiegand RA; LoRusso PM; Baker LH
    Clin Cancer Res; 1995 Aug; 1(8):831-7. PubMed ID: 9816052
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Improved safety, pharmacokinetics and therapeutic efficacy profiles of a novel liposomal formulation of mitoxantrone.
    Gokhale PC; Pei J; Zhang C; Ahmad I; Rahman A; Kasid U
    Anticancer Res; 2001; 21(5):3313-21. PubMed ID: 11848489
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vivo pharmacokinetic features, toxicity profile, and chemosensitizing activity of alpha-cyano-beta-hydroxy-beta- methyl-N-(2,5-dibromophenyl)propenamide (LFM-A13), a novel antileukemic agent targeting Bruton's tyrosine kinase.
    Uckun FM; Zheng Y; Cetkovic-Cvrlje M; Vassilev A; Lisowski E; Waurzyniak B; Chen H; Carpenter R; Chen CL
    Clin Cancer Res; 2002 May; 8(5):1224-33. PubMed ID: 12006542
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.
    EFSA GMO Panel Working Group on Animal Feeding Trials
    Food Chem Toxicol; 2008 Mar; 46 Suppl 1():S2-70. PubMed ID: 18328408
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Murine toxicology and pharmacology of UAB-8, a conformationally constrained analog of retinoic acid.
    Lin TH; Rogers TS; Hill DL; Simpson-Herren L; Farnell DR; Kochhar DM; Alam M; Brouillette WJ; Muccio DD
    Toxicol Appl Pharmacol; 1996 Aug; 139(2):310-6. PubMed ID: 8806847
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacological and toxicological aspects of 4-demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548): a novel antineoplastic agent.
    Geroni C; Ripamonti M; Arrigoni C; Fiorentini F; Capolongo L; Moneta D; Marchini S; Della Torre P; Albanese C; Lamparelli MG; Ciomei M; Rossi R; Caruso M
    Cancer Res; 2001 Mar; 61(5):1983-90. PubMed ID: 11280756
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin.
    Int J Toxicol; 2007; 26 Suppl 1():3-106. PubMed ID: 17365137
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The area under the concentration-time curve of all-trans-retinoic acid is the most suitable pharmacokinetic correlate to the embryotoxicity of this retinoid in the rat.
    Tzimas G; Thiel R; Chahoud I; Nau H
    Toxicol Appl Pharmacol; 1997 Apr; 143(2):436-44. PubMed ID: 9144460
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparative pharmacokinetics of RAD001 (everolimus) in normal and tumor-bearing rodents.
    O'Reilly T; McSheehy PM; Kawai R; Kretz O; McMahon L; Brueggen J; Bruelisauer A; Gschwind HP; Allegrini PR; Lane HA
    Cancer Chemother Pharmacol; 2010 Mar; 65(4):625-39. PubMed ID: 19784839
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.
    Girard D; Finegan SM; Dunne MW; Lame ME
    J Antimicrob Chemother; 2005 Aug; 56(2):365-71. PubMed ID: 16002421
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.