BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

83 related articles for article (PubMed ID: 17346540)

  • 1. Reduced progression of endometrial hyperplasia with oral mTOR inhibition in the Pten heterozygote murine model.
    Milam MR; Celestino J; Wu W; Broaddus RR; Schmeler KM; Slomovitz BM; Soliman PT; Gershenson DM; Wang H; Ellenson LH; Lu KH
    Am J Obstet Gynecol; 2007 Mar; 196(3):247.e1-5. PubMed ID: 17346540
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Overactive mTOR signaling leads to endometrial hyperplasia in aged women and mice.
    Bajwa P; Nielsen S; Lombard JM; Rassam L; Nahar P; Rueda BR; Wilkinson JE; Miller RA; Tanwar PS
    Oncotarget; 2017 Jan; 8(5):7265-7275. PubMed ID: 27980219
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Loss of phosphatase and tensin homologue deleted on chromosome 10 and phosphorylation of mammalian target of rapamycin are associated with progesterone refractory endometrial hyperplasia.
    Milam MR; Soliman PT; Chung LH; Schmeler KM; Bassett RL; Broaddus RR; Lu KH
    Int J Gynecol Cancer; 2008; 18(1):146-51. PubMed ID: 17466036
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Primary chemoprevention of endometrial hyperplasia with the peroxisome proliferator-activated receptor gamma agonist rosiglitazone in the PTEN heterozygote murine model.
    Wu W; Celestino J; Milam MR; Schmeler KM; Broaddus RR; Ellenson LH; Lu KH
    Int J Gynecol Cancer; 2008; 18(2):329-38. PubMed ID: 18334011
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PTEN sequence analysis in endometrial hyperplasia and endometrial carcinoma in Slovak women.
    Gbelcová H; Bakeš P; Priščáková P; Šišovský V; Hojsíková I; Straka Ľ; Konečný M; Markus J; D'Acunto CW; Ruml T; Böhmer D; Danihel Ľ; Repiská V
    Anal Cell Pathol (Amst); 2015; 2015():746856. PubMed ID: 26114084
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mammalian target of rapamycin inhibition as therapy for hematologic malignancies.
    Panwalkar A; Verstovsek S; Giles FJ
    Cancer; 2004 Feb; 100(4):657-66. PubMed ID: 14770419
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Combined targeting of FGFR2 and mTOR by ponatinib and ridaforolimus results in synergistic antitumor activity in FGFR2 mutant endometrial cancer models.
    Gozgit JM; Squillace RM; Wongchenko MJ; Miller D; Wardwell S; Mohemmad Q; Narasimhan NI; Wang F; Clackson T; Rivera VM
    Cancer Chemother Pharmacol; 2013 May; 71(5):1315-23. PubMed ID: 23468082
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasias.
    Mirantes C; Eritja N; Dosil MA; Santacana M; Pallares J; Gatius S; Bergadà L; Maiques O; Matias-Guiu X; Dolcet X
    Dis Model Mech; 2013 May; 6(3):710-20. PubMed ID: 23471917
    [TBL] [Abstract][Full Text] [Related]  

  • 9. RAD001 (Everolimus) Can prevent tamoxifen-related endometrial and stromal hyperplasia.
    Erdemoglu E; Güney M; Take G; Giray SG; Mungan T
    Int J Gynecol Cancer; 2009 Apr; 19(3):375-9. PubMed ID: 19407562
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.
    Neshat MS; Mellinghoff IK; Tran C; Stiles B; Thomas G; Petersen R; Frost P; Gibbons JJ; Wu H; Sawyers CL
    Proc Natl Acad Sci U S A; 2001 Aug; 98(18):10314-9. PubMed ID: 11504908
    [TBL] [Abstract][Full Text] [Related]  

  • 11. mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo.
    Kwon CH; Zhu X; Zhang J; Baker SJ
    Proc Natl Acad Sci U S A; 2003 Oct; 100(22):12923-8. PubMed ID: 14534328
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells.
    Cao C; Subhawong T; Albert JM; Kim KW; Geng L; Sekhar KR; Gi YJ; Lu B
    Cancer Res; 2006 Oct; 66(20):10040-7. PubMed ID: 17047067
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PTEN as a predictive marker of response to conservative treatment in endometrial hyperplasia and early endometrial cancer. A systematic review and meta-analysis.
    Travaglino A; Raffone A; Saccone G; Insabato L; Mollo A; De Placido G; Zullo F
    Eur J Obstet Gynecol Reprod Biol; 2018 Dec; 231():104-110. PubMed ID: 30342311
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Enhanced sensitivity of multiple myeloma cells containing PTEN mutations to CCI-779.
    Shi Y; Gera J; Hu L; Hsu JH; Bookstein R; Li W; Lichtenstein A
    Cancer Res; 2002 Sep; 62(17):5027-34. PubMed ID: 12208757
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PTEN mutations as predictive marker for the high-grade endometrial cancer development in slovak women.
    Gbelcová H; Gergely L; Šišovský V; Straka Ľ; Böhmer D; Pastoráková A; Sušienková K; Repiská V; Korbeľ M; Danihel Ľ; Priščáková P
    Physiol Res; 2022 Dec; 71(Suppl 1):S125-S135. PubMed ID: 36592448
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of mTOR inhibitors in nude mice with endometrial carcinoma and variable PTEN expression status.
    Fong P; Meng LR
    Med Sci Monit Basic Res; 2014 Sep; 20():146-52. PubMed ID: 25266877
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Association of mismatch repair deficiency with PTEN frameshift mutations in endometrial cancers and the precursors in a Japanese population.
    Kanaya T; Kyo S; Sakaguchi J; Maida Y; Nakamura M; Takakura M; Hashimoto M; Mizumoto Y; Inoue M
    Am J Clin Pathol; 2005 Jul; 124(1):89-96. PubMed ID: 15923161
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PTEN-induction in U251 glioma cells decreases the expression of insulin-like growth factor binding protein-2.
    Levitt RJ; Georgescu MM; Pollak M
    Biochem Biophys Res Commun; 2005 Nov; 336(4):1056-61. PubMed ID: 16154532
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lean Body Weight and Metformin Are Insufficient to Prevent Endometrial Hyperplasia in Mice Harboring Inactivating Mutations in PTEN.
    Iglesias DA; Zhang Q; Celestino J; Sun CC; Yates MS; Schmandt RE; Lu KH
    Oncology; 2017; 92(2):109-114. PubMed ID: 27931017
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA mismatch repair deficiency accelerates endometrial tumorigenesis in Pten heterozygous mice.
    Wang H; Douglas W; Lia M; Edelmann W; Kucherlapati R; Podsypanina K; Parsons R; Ellenson LH
    Am J Pathol; 2002 Apr; 160(4):1481-6. PubMed ID: 11943731
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.