These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 17349999)

  • 1. Zinc transporter 2 (SLC30A2) can suppress the vesicular zinc defect of adaptor protein 3-depleted fibroblasts by promoting zinc accumulation in lysosomes.
    Falcón-Pérez JM; Dell'Angelica EC
    Exp Cell Res; 2007 Apr; 313(7):1473-83. PubMed ID: 17349999
    [TBL] [Abstract][Full Text] [Related]  

  • 2. TNFα Post-Translationally Targets ZnT2 to Accumulate Zinc in Lysosomes.
    Hennigar SR; Kelleher SL
    J Cell Physiol; 2015 Oct; 230(10):2345-50. PubMed ID: 25808614
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ZnT2-overexpression represses the cytotoxic effects of zinc hyper-accumulation in malignant metallothionein-null T47D breast tumor cells.
    Lopez V; Foolad F; Kelleher SL
    Cancer Lett; 2011 May; 304(1):41-51. PubMed ID: 21353385
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ZnT2 is an electroneutral proton-coupled vesicular antiporter displaying an apparent stoichiometry of two protons per zinc ion.
    Golan Y; Alhadeff R; Warshel A; Assaraf YG
    PLoS Comput Biol; 2019 Mar; 15(3):e1006882. PubMed ID: 30893306
    [TBL] [Abstract][Full Text] [Related]  

  • 5. AP-3 and Rabip4' coordinately regulate spatial distribution of lysosomes.
    Ivan V; Martinez-Sanchez E; Sima LE; Oorschot V; Klumperman J; Petrescu SM; van der Sluijs P
    PLoS One; 2012; 7(10):e48142. PubMed ID: 23144738
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ZnT2 is a critical mediator of lysosomal-mediated cell death during early mammary gland involution.
    Hennigar SR; Seo YA; Sharma S; Soybel DI; Kelleher SL
    Sci Rep; 2015 Jan; 5():8033. PubMed ID: 25620235
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Vglut1 and ZnT3 co-targeting mechanisms regulate vesicular zinc stores in PC12 cells.
    Salazar G; Craige B; Love R; Kalman D; Faundez V
    J Cell Sci; 2005 May; 118(Pt 9):1911-21. PubMed ID: 15860731
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Prolactin (PRL)-stimulated ubiquitination of ZnT2 mediates a transient increase in zinc secretion followed by ZnT2 degradation in mammary epithelial cells.
    Seo YA; Lee S; Hennigar SR; Kelleher SL
    J Biol Chem; 2014 Aug; 289(34):23653-61. PubMed ID: 25016022
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Zinc transporter 2 interacts with vacuolar ATPase and is required for polarization, vesicle acidification, and secretion in mammary epithelial cells.
    Lee S; Rivera OC; Kelleher SL
    J Biol Chem; 2017 Dec; 292(52):21598-21613. PubMed ID: 29114036
    [TBL] [Abstract][Full Text] [Related]  

  • 10. STAT5-glucocorticoid receptor interaction and MTF-1 regulate the expression of ZnT2 (Slc30a2) in pancreatic acinar cells.
    Guo L; Lichten LA; Ryu MS; Liuzzi JP; Wang F; Cousins RJ
    Proc Natl Acad Sci U S A; 2010 Feb; 107(7):2818-23. PubMed ID: 20133611
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Adaptor protein complexes AP-1 and AP-3 are required by the HHV-7 Immunoevasin U21 for rerouting of class I MHC molecules to the lysosomal compartment.
    Kimpler LA; Glosson NL; Downs D; Gonyo P; May NA; Hudson AW
    PLoS One; 2014; 9(6):e99139. PubMed ID: 24901711
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evaluation of the roles of the cytosolic N-terminus and His-rich loop of ZNT proteins using ZNT2 and ZNT3 chimeric mutants.
    Fukue K; Itsumura N; Tsuji N; Nishino K; Nagao M; Narita H; Kambe T
    Sci Rep; 2018 Sep; 8(1):14084. PubMed ID: 30237557
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A common genetic variant in zinc transporter ZnT2 (Thr288Ser) is present in women with low milk volume and alters lysosome function and cell energetics.
    Rivera OC; Geddes DT; Barber-Zucker S; Zarivach R; Gagnon A; Soybel DI; Kelleher SL
    Am J Physiol Cell Physiol; 2020 Jun; 318(6):C1166-C1177. PubMed ID: 32320289
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Zinc-dependent lysosomal enlargement in TRPML1-deficient cells involves MTF-1 transcription factor and ZnT4 (Slc30a4) transporter.
    Kukic I; Lee JK; Coblentz J; Kelleher SL; Kiselyov K
    Biochem J; 2013 Apr; 451(2):155-63. PubMed ID: 23368743
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The effects of transformation and ZnT-1 silencing on zinc homeostasis in cultured cells.
    Sankavaram K; Freake HC
    J Nutr Biochem; 2012 Jun; 23(6):629-34. PubMed ID: 21775119
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The endo-lysosomal sorting machinery interacts with the intermediate filament cytoskeleton.
    Styers ML; Salazar G; Love R; Peden AA; Kowalczyk AP; Faundez V
    Mol Biol Cell; 2004 Dec; 15(12):5369-82. PubMed ID: 15456899
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Functional analysis of two single nucleotide polymorphisms in SLC30A2 (ZnT2): implications for mammary gland function and breast disease in women.
    Seo YA; Kelleher SL
    Physiol Genomics; 2010 Nov; 42A(4):219-27. PubMed ID: 20858712
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Zinc transporter-2 (ZnT2) variants are localized to distinct subcellular compartments and functionally transport zinc.
    Lopez V; Kelleher SL
    Biochem J; 2009 Jul; 422(1):43-52. PubMed ID: 19496757
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Exome Sequencing of SLC30A2 Identifies Novel Loss- and Gain-of-Function Variants Associated with Breast Cell Dysfunction.
    Alam S; Hennigar SR; Gallagher C; Soybel DI; Kelleher SL
    J Mammary Gland Biol Neoplasia; 2015 Dec; 20(3-4):159-72. PubMed ID: 26293594
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Prolactin receptor attenuation induces zinc pool redistribution through ZnT2 and decreases invasion in MDA-MB-453 breast cancer cells.
    Bostanci Z; Alam S; Soybel DI; Kelleher SL
    Exp Cell Res; 2014 Feb; 321(2):190-200. PubMed ID: 24333596
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.