207 related articles for article (PubMed ID: 17351105)
1. Chlorambucil cytotoxicity in malignant B lymphocytes is synergistically increased by 2-(morpholin-4-yl)-benzo[h]chomen-4-one (NU7026)-mediated inhibition of DNA double-strand break repair via inhibition of DNA-dependent protein kinase.
Amrein L; Loignon M; Goulet AC; Dunn M; Jean-Claude B; Aloyz R; Panasci L
J Pharmacol Exp Ther; 2007 Jun; 321(3):848-55. PubMed ID: 17351105
[TBL] [Abstract][Full Text] [Related]
2. DNA-dependent protein kinase: effect on DSB repair, G2/M checkpoint and mode of cell death in NSCLC cell lines.
Sak A; Groneberg M; Stuschke M
Int J Radiat Biol; 2019 Sep; 95(9):1205-1219. PubMed ID: 31287365
[No Abstract] [Full Text] [Related]
3. Human chronic lymphocytic leukemia B cells can escape DNA damage-induced apoptosis through the nonhomologous end-joining DNA repair pathway.
Deriano L; Guipaud O; Merle-Béral H; Binet JL; Ricoul M; Potocki-Veronese G; Favaudon V; Maciorowski Z; Muller C; Salles B; Sabatier L; Delic J
Blood; 2005 Jun; 105(12):4776-83. PubMed ID: 15718417
[TBL] [Abstract][Full Text] [Related]
4. A novel DNA-dependent protein kinase inhibitor, NU7026, potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia.
Willmore E; de Caux S; Sunter NJ; Tilby MJ; Jackson GH; Austin CA; Durkacz BW
Blood; 2004 Jun; 103(12):4659-65. PubMed ID: 15010369
[TBL] [Abstract][Full Text] [Related]
5. Potentiation of chlorambucil cytotoxicity in B-cell chronic lymphocytic leukemia by inhibition of DNA-dependent protein kinase activity using wortmannin.
Christodoulopoulos G; Muller C; Salles B; Kazmi R; Panasci L
Cancer Res; 1998 May; 58(9):1789-92. PubMed ID: 9581813
[TBL] [Abstract][Full Text] [Related]
6. DNA-PK inhibition causes a low level of H2AX phosphorylation and homologous recombination repair in Medaka (Oryzias latipes) cells.
Urushihara Y; Kobayashi J; Matsumoto Y; Komatsu K; Oda S; Mitani H
Biochem Biophys Res Commun; 2012 Dec; 429(3-4):131-6. PubMed ID: 23142596
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of DNA-dependent protein kinase catalytic subunit by small molecule inhibitor NU7026 sensitizes human leukemic K562 cells to benzene metabolite-induced apoptosis.
You H; Kong MM; Wang LP; Xiao X; Liao HL; Bi ZY; Yan H; Wang H; Wang CH; Ma Q; Liu YQ; Bi YY
J Huazhong Univ Sci Technolog Med Sci; 2013 Feb; 33(1):43-50. PubMed ID: 23392706
[TBL] [Abstract][Full Text] [Related]
8. Imatinib sensitizes CLL lymphocytes to chlorambucil.
Aloyz R; Grzywacz K; Xu ZY; Loignon M; Alaoui-Jamali MA; Panasci L
Leukemia; 2004 Mar; 18(3):409-14. PubMed ID: 14712290
[TBL] [Abstract][Full Text] [Related]
9. Dual inhibition of the homologous recombinational repair and the nonhomologous end-joining repair pathways in chronic lymphocytic leukemia therapy.
Amrein L; Davidson D; Shawi M; Petruccelli LA; Miller WH; Aloyz R; Panasci L
Leuk Res; 2011 Aug; 35(8):1080-6. PubMed ID: 21281966
[TBL] [Abstract][Full Text] [Related]
10. Activation of DNA damage repair pathways in response to nitrogen mustard-induced DNA damage and toxicity in skin keratinocytes.
Inturi S; Tewari-Singh N; Agarwal C; White CW; Agarwal R
Mutat Res; 2014; 763-764():53-63. PubMed ID: 24732344
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of DNA-PK enhances chemosensitivity of B-cell precursor acute lymphoblastic leukemia cells to doxorubicin.
Alikarami F; Safa M; Faranoush M; Hayat P; Kazemi A
Biomed Pharmacother; 2017 Oct; 94():1077-1093. PubMed ID: 28821159
[TBL] [Abstract][Full Text] [Related]
12. DNA-Dependent Protein Kinase As Molecular Target for Radiosensitization of Neuroblastoma Cells.
Dolman ME; van der Ploeg I; Koster J; Bate-Eya LT; Versteeg R; Caron HN; Molenaar JJ
PLoS One; 2015; 10(12):e0145744. PubMed ID: 26716839
[TBL] [Abstract][Full Text] [Related]
13. Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1.
Veuger SJ; Curtin NJ; Richardson CJ; Smith GC; Durkacz BW
Cancer Res; 2003 Sep; 63(18):6008-15. PubMed ID: 14522929
[TBL] [Abstract][Full Text] [Related]
14. DNA-PK promotes the survival of young neurons in the embryonic mouse retina.
Baleriola J; Suárez T; de la Rosa EJ
Cell Death Differ; 2010 Nov; 17(11):1697-706. PubMed ID: 20448641
[TBL] [Abstract][Full Text] [Related]
15. Chlorambucil induction of HsRad51 in B-cell chronic lymphocytic leukemia.
Christodoulopoulos G; Malapetsa A; Schipper H; Golub E; Radding C; Panasci LC
Clin Cancer Res; 1999 Aug; 5(8):2178-84. PubMed ID: 10473103
[TBL] [Abstract][Full Text] [Related]
16. DNA-dependent protein kinase is a therapeutic target and an indicator of poor prognosis in B-cell chronic lymphocytic leukemia.
Willmore E; Elliott SL; Mainou-Fowler T; Summerfield GP; Jackson GH; O'Neill F; Lowe C; Carter A; Harris R; Pettitt AR; Cano-Soumillac C; Griffin RJ; Cowell IG; Austin CA; Durkacz BW
Clin Cancer Res; 2008 Jun; 14(12):3984-92. PubMed ID: 18559621
[TBL] [Abstract][Full Text] [Related]
17. Suppression of DNA-dependent protein kinase sensitize cells to radiation without affecting DSB repair.
Gustafsson AS; Abramenkovs A; Stenerlöw B
Mutat Res; 2014 Nov; 769():1-10. PubMed ID: 25771720
[TBL] [Abstract][Full Text] [Related]
18. Preclinical evaluation of a potent novel DNA-dependent protein kinase inhibitor NU7441.
Zhao Y; Thomas HD; Batey MA; Cowell IG; Richardson CJ; Griffin RJ; Calvert AH; Newell DR; Smith GC; Curtin NJ
Cancer Res; 2006 May; 66(10):5354-62. PubMed ID: 16707462
[TBL] [Abstract][Full Text] [Related]
19. Nontoxic concentration of DNA-PK inhibitor NU7441 radio-sensitizes lung tumor cells with little effect on double strand break repair.
Sunada S; Kanai H; Lee Y; Yasuda T; Hirakawa H; Liu C; Fujimori A; Uesaka M; Okayasu R
Cancer Sci; 2016 Sep; 107(9):1250-5. PubMed ID: 27341700
[TBL] [Abstract][Full Text] [Related]
20. DNA-PK inhibition by NU7441 sensitizes breast cancer cells to ionizing radiation and doxorubicin.
Ciszewski WM; Tavecchio M; Dastych J; Curtin NJ
Breast Cancer Res Treat; 2014 Jan; 143(1):47-55. PubMed ID: 24292814
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
