212 related articles for article (PubMed ID: 17352932)
1. Progressive CAG expansion in the brain of a novel R6/1-89Q mouse model of Huntington's disease with delayed phenotypic onset.
Vatsavayai SC; Dallérac GM; Milnerwood AJ; Cummings DM; Rezaie P; Murphy KP; Hirst MC
Brain Res Bull; 2007 Apr; 72(2-3):98-102. PubMed ID: 17352932
[TBL] [Abstract][Full Text] [Related]
2. Paradoxical delay in the onset of disease caused by super-long CAG repeat expansions in R6/2 mice.
Morton AJ; Glynn D; Leavens W; Zheng Z; Faull RL; Skepper JN; Wight JM
Neurobiol Dis; 2009 Mar; 33(3):331-41. PubMed ID: 19130884
[TBL] [Abstract][Full Text] [Related]
3. CAG repeat lengths > or =335 attenuate the phenotype in the R6/2 Huntington's disease transgenic mouse.
Dragatsis I; Goldowitz D; Del Mar N; Deng YP; Meade CA; Liu L; Sun Z; Dietrich P; Yue J; Reiner A
Neurobiol Dis; 2009 Mar; 33(3):315-30. PubMed ID: 19027857
[TBL] [Abstract][Full Text] [Related]
4. Transgenic mice expressing mutated full-length HD cDNA: a paradigm for locomotor changes and selective neuronal loss in Huntington's disease.
Reddy PH; Charles V; Williams M; Miller G; Whetsell WO; Tagle DA
Philos Trans R Soc Lond B Biol Sci; 1999 Jun; 354(1386):1035-45. PubMed ID: 10434303
[TBL] [Abstract][Full Text] [Related]
5. Neuronal aggregates are associated with phenotypic onset in the R6/2 Huntington's disease transgenic mouse.
Cowin RM; Roscic A; Bui N; Graham D; Paganetti P; Jankowsky JL; Weiss A; Paylor R
Behav Brain Res; 2012 Apr; 229(2):308-19. PubMed ID: 22306231
[TBL] [Abstract][Full Text] [Related]
6. A critical window of CAG repeat-length correlates with phenotype severity in the R6/2 mouse model of Huntington's disease.
Cummings DM; Alaghband Y; Hickey MA; Joshi PR; Hong SC; Zhu C; Ando TK; André VM; Cepeda C; Watson JB; Levine MS
J Neurophysiol; 2012 Jan; 107(2):677-91. PubMed ID: 22072510
[TBL] [Abstract][Full Text] [Related]
7. Similar Progression of Morphological and Metabolic Phenotype in R6/2 Mice with Different CAG Repeats Revealed by In Vivo Magnetic Resonance Imaging and Spectroscopy.
Sawiak SJ; Wood NI; Morton AJ
J Huntingtons Dis; 2016 Oct; 5(3):271-283. PubMed ID: 27662335
[TBL] [Abstract][Full Text] [Related]
8. Transcription elongation and tissue-specific somatic CAG instability.
Goula AV; Stys A; Chan JP; Trottier Y; Festenstein R; Merienne K
PLoS Genet; 2012; 8(11):e1003051. PubMed ID: 23209427
[TBL] [Abstract][Full Text] [Related]
9. Novel BAC Mouse Model of Huntington's Disease with 225 CAG Repeats Exhibits an Early Widespread and Stable Degenerative Phenotype.
Wegrzynowicz M; Bichell TJ; Soares BD; Loth MK; McGlothan JS; Mori S; Alikhan FS; Hua K; Coughlin JM; Holt HK; Jetter CS; Pomper MG; Osmand AP; Guilarte TR; Bowman AB
J Huntingtons Dis; 2015; 4(1):17-36. PubMed ID: 26333255
[TBL] [Abstract][Full Text] [Related]
10. Centrosome disorganization in fibroblast cultures derived from R6/2 Huntington's disease (HD) transgenic mice and HD patients.
Sathasivam K; Woodman B; Mahal A; Bertaux F; Wanker EE; Shima DT; Bates GP
Hum Mol Genet; 2001 Oct; 10(21):2425-35. PubMed ID: 11689489
[TBL] [Abstract][Full Text] [Related]
11. Early Neurodegeneration in R6/2 Mice Carrying the Huntington's Disease Mutation with a Super-Expanded CAG Repeat, Despite Normal Lifespan.
Kielar C; Morton AJ
J Huntingtons Dis; 2018; 7(1):61-76. PubMed ID: 29480204
[TBL] [Abstract][Full Text] [Related]
12. A CAG repeat threshold for therapeutics targeting somatic instability in Huntington's disease.
Aldous SG; Smith EJ; Landles C; Osborne GF; Cañibano-Pico M; Nita IM; Phillips J; Zhang Y; Jin B; Hirst MB; Benn CL; Bond BC; Edelmann W; Greene JR; Bates GP
Brain; 2024 May; 147(5):1784-1798. PubMed ID: 38387080
[TBL] [Abstract][Full Text] [Related]
13. Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
Mangiarini L; Sathasivam K; Seller M; Cozens B; Harper A; Hetherington C; Lawton M; Trottier Y; Lehrach H; Davies SW; Bates GP
Cell; 1996 Nov; 87(3):493-506. PubMed ID: 8898202
[TBL] [Abstract][Full Text] [Related]
14. Sex differences in behavior and striatal ascorbate release in the 140 CAG knock-in mouse model of Huntington's disease.
Dorner JL; Miller BR; Barton SJ; Brock TJ; Rebec GV
Behav Brain Res; 2007 Mar; 178(1):90-7. PubMed ID: 17239451
[TBL] [Abstract][Full Text] [Related]
15. Weight loss in Huntington disease increases with higher CAG repeat number.
Aziz NA; van der Burg JM; Landwehrmeyer GB; Brundin P; Stijnen T; ; Roos RA
Neurology; 2008 Nov; 71(19):1506-13. PubMed ID: 18981372
[TBL] [Abstract][Full Text] [Related]
16. Compensatory changes in the ubiquitin-proteasome system, brain-derived neurotrophic factor and mitochondrial complex II/III in YAC72 and R6/2 transgenic mice partially model Huntington's disease patients.
Seo H; Kim W; Isacson O
Hum Mol Genet; 2008 Oct; 17(20):3144-53. PubMed ID: 18640989
[TBL] [Abstract][Full Text] [Related]
17. Transgenic rat model of Huntington's disease.
von Hörsten S; Schmitt I; Nguyen HP; Holzmann C; Schmidt T; Walther T; Bader M; Pabst R; Kobbe P; Krotova J; Stiller D; Kask A; Vaarmann A; Rathke-Hartlieb S; Schulz JB; Grasshoff U; Bauer I; Vieira-Saecker AM; Paul M; Jones L; Lindenberg KS; Landwehrmeyer B; Bauer A; Li XJ; Riess O
Hum Mol Genet; 2003 Mar; 12(6):617-24. PubMed ID: 12620967
[TBL] [Abstract][Full Text] [Related]
18. Continuous and periodic expansion of CAG repeats in Huntington's disease R6/1 mice.
Møllersen L; Rowe AD; Larsen E; Rognes T; Klungland A
PLoS Genet; 2010 Dec; 6(12):e1001242. PubMed ID: 21170307
[TBL] [Abstract][Full Text] [Related]
19. The Hdh(Q150/Q150) knock-in mouse model of HD and the R6/2 exon 1 model develop comparable and widespread molecular phenotypes.
Woodman B; Butler R; Landles C; Lupton MK; Tse J; Hockly E; Moffitt H; Sathasivam K; Bates GP
Brain Res Bull; 2007 Apr; 72(2-3):83-97. PubMed ID: 17352931
[TBL] [Abstract][Full Text] [Related]
20. Chronology of behavioral symptoms and neuropathological sequela in R6/2 Huntington's disease transgenic mice.
Stack EC; Kubilus JK; Smith K; Cormier K; Del Signore SJ; Guelin E; Ryu H; Hersch SM; Ferrante RJ
J Comp Neurol; 2005 Oct; 490(4):354-70. PubMed ID: 16127709
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
