618 related articles for article (PubMed ID: 17353198)
1. Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells.
Ji Z; Mei FC; Xie J; Cheng X
J Biol Chem; 2007 May; 282(19):14048-55. PubMed ID: 17353198
[TBL] [Abstract][Full Text] [Related]
2. KRAS(G12D)- and BRAF(V600E)-induced transformation of murine pancreatic epithelial cells requires MEK/ERK-stimulated IGF1R signaling.
Appleman VA; Ahronian LG; Cai J; Klimstra DS; Lewis BC
Mol Cancer Res; 2012 Sep; 10(9):1228-39. PubMed ID: 22871572
[TBL] [Abstract][Full Text] [Related]
3. Stromal response to Hedgehog signaling restrains pancreatic cancer progression.
Lee JJ; Perera RM; Wang H; Wu DC; Liu XS; Han S; Fitamant J; Jones PD; Ghanta KS; Kawano S; Nagle JM; Deshpande V; Boucher Y; Kato T; Chen JK; Willmann JK; Bardeesy N; Beachy PA
Proc Natl Acad Sci U S A; 2014 Jul; 111(30):E3091-100. PubMed ID: 25024225
[TBL] [Abstract][Full Text] [Related]
4. Cross-signaling among phosphinositide-3 kinase, mitogen-activated protein kinase and sonic hedgehog pathways exists in esophageal cancer.
Wei L; Xu Z
Int J Cancer; 2011 Jul; 129(2):275-84. PubMed ID: 20839260
[TBL] [Abstract][Full Text] [Related]
5. Activation of phosphatidylinositol 3-kinase and extracellular signal-regulated kinase is required for glial cell line-derived neurotrophic factor-induced migration and invasion of pancreatic carcinoma cells.
Veit C; Genze F; Menke A; Hoeffert S; Gress TM; Gierschik P; Giehl K
Cancer Res; 2004 Aug; 64(15):5291-300. PubMed ID: 15289335
[TBL] [Abstract][Full Text] [Related]
6. Ribonucleoprotein HNRNPA2B1 interacts with and regulates oncogenic KRAS in pancreatic ductal adenocarcinoma cells.
Barceló C; Etchin J; Mansour MR; Sanda T; Ginesta MM; Sanchez-Arévalo Lobo VJ; Real FX; Capellà G; Estanyol JM; Jaumot M; Look AT; Agell N
Gastroenterology; 2014 Oct; 147(4):882-892.e8. PubMed ID: 24998203
[TBL] [Abstract][Full Text] [Related]
7. Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.
Stecca B; Mas C; Clement V; Zbinden M; Correa R; Piguet V; Beermann F; Ruiz i Altaba A
Proc Natl Acad Sci U S A; 2007 Apr; 104(14):5895-900. PubMed ID: 17392427
[TBL] [Abstract][Full Text] [Related]
8. Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway.
Schnidar H; Eberl M; Klingler S; Mangelberger D; Kasper M; Hauser-Kronberger C; Regl G; Kroismayr R; Moriggl R; Sibilia M; Aberger F
Cancer Res; 2009 Feb; 69(4):1284-92. PubMed ID: 19190345
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of the RAF/MEK/ERK Signaling Cascade in Pancreatic Cancer: Recent Advances and Future Perspectives.
Adamopoulos C; Cave DD; Papavassiliou AG
Int J Mol Sci; 2024 Jan; 25(3):. PubMed ID: 38338909
[TBL] [Abstract][Full Text] [Related]
10. Loss of Somatostatin Receptor Subtype 2 Promotes Growth of KRAS-Induced Pancreatic Tumors in Mice by Activating PI3K Signaling and Overexpression of CXCL16.
Chalabi-Dchar M; Cassant-Sourdy S; Duluc C; Fanjul M; Lulka H; Samain R; Roche C; Breibach F; Delisle MB; Poupot M; Dufresne M; Shimaoka T; Yonehara S; Mathonnet M; Pyronnet S; Bousquet C
Gastroenterology; 2015 Jun; 148(7):1452-65. PubMed ID: 25683115
[TBL] [Abstract][Full Text] [Related]
11. A central role for RAF→MEK→ERK signaling in the genesis of pancreatic ductal adenocarcinoma.
Collisson EA; Trejo CL; Silva JM; Gu S; Korkola JE; Heiser LM; Charles RP; Rabinovich BA; Hann B; Dankort D; Spellman PT; Phillips WA; Gray JW; McMahon M
Cancer Discov; 2012 Aug; 2(8):685-93. PubMed ID: 22628411
[TBL] [Abstract][Full Text] [Related]
12. Regulation of the hedgehog signaling by the mitogen-activated protein kinase cascade in gastric cancer.
Seto M; Ohta M; Asaoka Y; Ikenoue T; Tada M; Miyabayashi K; Mohri D; Tanaka Y; Ijichi H; Tateishi K; Kanai F; Kawabe T; Omata M
Mol Carcinog; 2009 Aug; 48(8):703-12. PubMed ID: 19142899
[TBL] [Abstract][Full Text] [Related]
13. PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice.
Wu CY; Carpenter ES; Takeuchi KK; Halbrook CJ; Peverley LV; Bien H; Hall JC; DelGiorno KE; Pal D; Song Y; Shi C; Lin RZ; Crawford HC
Gastroenterology; 2014 Dec; 147(6):1405-16.e7. PubMed ID: 25311989
[TBL] [Abstract][Full Text] [Related]
14. SCL/TAL1 interrupting locus derepresses GLI1 from the negative control of suppressor-of-fused in pancreatic cancer cell.
Kasai K; Inaguma S; Yoneyama A; Yoshikawa K; Ikeda H
Cancer Res; 2008 Oct; 68(19):7723-9. PubMed ID: 18829525
[TBL] [Abstract][Full Text] [Related]
15. A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors.
Loboda A; Nebozhyn M; Klinghoffer R; Frazier J; Chastain M; Arthur W; Roberts B; Zhang T; Chenard M; Haines B; Andersen J; Nagashima K; Paweletz C; Lynch B; Feldman I; Dai H; Huang P; Watters J
BMC Med Genomics; 2010 Jun; 3():26. PubMed ID: 20591134
[TBL] [Abstract][Full Text] [Related]
16. Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer.
Eser S; Reiff N; Messer M; Seidler B; Gottschalk K; Dobler M; Hieber M; Arbeiter A; Klein S; Kong B; Michalski CW; Schlitter AM; Esposito I; Kind AJ; Rad L; Schnieke AE; Baccarini M; Alessi DR; Rad R; Schmid RM; Schneider G; Saur D
Cancer Cell; 2013 Mar; 23(3):406-20. PubMed ID: 23453624
[TBL] [Abstract][Full Text] [Related]
17. In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors.
Benvenuto M; Masuelli L; De Smaele E; Fantini M; Mattera R; Cucchi D; Bonanno E; Di Stefano E; Frajese GV; Orlandi A; Screpanti I; Gulino A; Modesti A; Bei R
Oncotarget; 2016 Feb; 7(8):9250-70. PubMed ID: 26843616
[TBL] [Abstract][Full Text] [Related]
18. Receptor tyrosine kinases exert dominant control over PI3K signaling in human KRAS mutant colorectal cancers.
Ebi H; Corcoran RB; Singh A; Chen Z; Song Y; Lifshits E; Ryan DP; Meyerhardt JA; Benes C; Settleman J; Wong KK; Cantley LC; Engelman JA
J Clin Invest; 2011 Nov; 121(11):4311-21. PubMed ID: 21985784
[TBL] [Abstract][Full Text] [Related]
19. ErbB2 signaling activates the Hedgehog pathway via PI3K-Akt in human esophageal adenocarcinoma: identification of novel targets for concerted therapy concepts.
Kebenko M; Drenckhan A; Gros SJ; Jücker M; Grabinski N; Ewald F; Grottke A; Schultze A; Izbicki JR; Bokemeyer C; Wellbrock J; Fiedler W
Cell Signal; 2015 Feb; 27(2):373-81. PubMed ID: 25435423
[TBL] [Abstract][Full Text] [Related]
20. Targeting the prohibitin scaffold-CRAF kinase interaction in RAS-ERK-driven pancreatic ductal adenocarcinoma.
Luan Z; He Y; Alattar M; Chen Z; He F
Mol Cancer; 2014 Feb; 13():38. PubMed ID: 24568222
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]