BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

259 related articles for article (PubMed ID: 17356576)

  • 1. SB-649915-B, a novel 5-HT1A/B autoreceptor antagonist and serotonin reuptake inhibitor, is anxiolytic and displays fast onset activity in the rat high light social interaction test.
    Starr KR; Price GW; Watson JM; Atkinson PJ; Arban R; Melotto S; Dawson LA; Hagan JJ; Upton N; Duxon MS
    Neuropsychopharmacology; 2007 Oct; 32(10):2163-72. PubMed ID: 17356576
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of the potent 5-HT(1A/B) receptor antagonist and serotonin reuptake inhibitor SB-649915: preclinical evidence for hastened onset of antidepressant/anxiolytic efficacy.
    Watson JM; Dawson LA
    CNS Drug Rev; 2007; 13(2):206-23. PubMed ID: 17627673
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SB-649915, a novel, potent 5-HT1A and 5-HT1B autoreceptor antagonist and 5-HT re-uptake inhibitor in native tissue.
    Scott C; Soffin EM; Hill M; Atkinson PJ; Langmead CJ; Wren PB; Faedo S; Gordon LJ; Price GW; Bromidge S; Johnson CN; Hagan JJ; Watson J
    Eur J Pharmacol; 2006 Apr; 536(1-2):54-61. PubMed ID: 16571351
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Simultaneous blockade of 5-HT1A/B receptors and 5-HT transporters results in acute increases in extracellular 5-HT in both rats and guinea pigs: in vivo characterization of the novel 5-HT1A/B receptor antagonist/5-HT transport inhibitor SB-649915-B.
    Hughes ZA; Starr KR; Scott CM; Newson MJ; Sharp T; Watson JM; Hagan JJ; Dawson LA
    Psychopharmacology (Berl); 2007 May; 192(1):121-33. PubMed ID: 17265079
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterisation of the selective 5-HT1B receptor antagonist SB-616234-A (1-[6-(cis-3,5-dimethylpiperazin-1-yl)-2,3-dihydro-5-methoxyindol-1-yl]-1-[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride): in vivo neurochemical and behavioural evidence of anxiolytic/antidepressant activity.
    Dawson LA; Hughes ZA; Starr KR; Storey JD; Bettelini L; Bacchi F; Arban R; Poffe A; Melotto S; Hagan JJ; Price GW
    Neuropharmacology; 2006 Jun; 50(8):975-83. PubMed ID: 16581092
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effect of a selective 5-HT reuptake inhibitor in combination with 5-HT1A and 5-HT1B receptor antagonists on extracellular 5-HT in rat frontal cortex in vivo.
    Sharp T; Umbers V; Gartside SE
    Br J Pharmacol; 1997 Jul; 121(5):941-6. PubMed ID: 9222551
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Blockade of 5-HT1A receptors by (+/-)-pindolol potentiates cortical 5-HT outflow, but not antidepressant-like activity of paroxetine: microdialysis and behavioral approaches in 5-HT1A receptor knockout mice.
    Guilloux JP; David DJ; Guiard BP; Chenu F; Repérant C; Toth M; Bourin M; Gardier AM
    Neuropsychopharmacology; 2006 Oct; 31(10):2162-72. PubMed ID: 16452992
    [TBL] [Abstract][Full Text] [Related]  

  • 8. S41744, a dual neurokinin (NK)1 receptor antagonist and serotonin (5-HT) reuptake inhibitor with potential antidepressant properties: a comparison to aprepitant (MK869) and paroxetine.
    Millan MJ; Dekeyne A; Gobert A; Mannoury la Cour C; Brocco M; Rivet JM; Di Cara B; Lejeune F; Cremers TI; Flik G; de Jong TR; Olivier B; de Nanteuil G
    Eur Neuropsychopharmacol; 2010 Sep; 20(9):599-621. PubMed ID: 20483567
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Latency to paroxetine-induced anxiolysis in the rat is reduced by co-administration of the 5-HT(1A) receptor antagonist WAY100635.
    Duxon MS; Starr KR; Upton N
    Br J Pharmacol; 2000 Aug; 130(7):1713-9. PubMed ID: 10928979
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 5-HT1A receptors are differentially involved in the anxiolytic- and antidepressant-like effects of 8-OH-DPAT and fluoxetine in the rat.
    De Vry J; Schreiber R; Melon C; Dalmus M; Jentzsch KR
    Eur Neuropsychopharmacol; 2004 Dec; 14(6):487-95. PubMed ID: 15589388
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of co-administration of the selective 5-HT1A receptor antagonist WAY 100,635 and selective 5-HT1B/1D receptor antagonist GR 127,935 on anxiolytic effect of citalopram in conditioned fear stress in the rat.
    Muraki I; Inoue T; Koyama T
    Eur J Pharmacol; 2008 May; 586(1-3):171-8. PubMed ID: 18423441
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The role of 5-HT receptor subtypes in the anxiolytic effects of selective serotonin reuptake inhibitors in the rat ultrasonic vocalization test.
    Schreiber R; Melon C; De Vry J
    Psychopharmacology (Berl); 1998 Feb; 135(4):383-91. PubMed ID: 9539263
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/serotonin reuptake inhibitor, vilazodone.
    Hughes ZA; Starr KR; Langmead CJ; Hill M; Bartoszyk GD; Hagan JJ; Middlemiss DN; Dawson LA
    Eur J Pharmacol; 2005 Mar; 510(1-2):49-57. PubMed ID: 15740724
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of the potential antidepressant OPC-14523 [1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-methoxy-3,4-dihydro-2-quinolinone monomethanesulfonate] a combined sigma and 5-HT1A ligand: modulation of neuronal activity in the dorsal raphe nucleus.
    Bermack JE; Haddjeri N; Debonnel G
    J Pharmacol Exp Ther; 2004 Aug; 310(2):578-83. PubMed ID: 15044555
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of different 5-HT1A receptor antagonists in combination with paroxetine on expression of the immediate-early gene Arc in rat brain.
    Tordera R; Pei Q; Newson M; Gray K; Sprakes M; Sharp T
    Neuropharmacology; 2003 Jun; 44(7):893-902. PubMed ID: 12726821
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Onset of the effects of the 5-HT1A antagonist, WAY-100635, alone, and in combination with paroxetine, on olfactory bulbectomy and 8-OH-DPAT-induced changes in the rat.
    Cryan JF; McGrath C; Leonard BE; Norman TR
    Pharmacol Biochem Behav; 1999 Jun; 63(2):333-8. PubMed ID: 10371664
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Use of Arc expression as a molecular marker of increased postsynaptic 5-HT function after SSRI/5-HT1A receptor antagonist co-administration.
    Castro E; Tordera RM; Hughes ZA; Pei Q; Sharp T
    J Neurochem; 2003 Jun; 85(6):1480-7. PubMed ID: 12787067
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tonic immobility in guinea pigs: a behavioural response for detecting an anxiolytic-like effect?
    Olsen CK; Hogg S; Lapiz MD
    Behav Pharmacol; 2002 Jul; 13(4):261-9. PubMed ID: 12218506
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Preclinical pharmacology of F-98214-TA, a novel potent serotonin and norepinephrine uptake inhibitor with antidepressant and anxiolytic properties.
    Artaiz I; Zazpe A; Innerárity A; Del Olmo E; Díaz A; Ruiz-Ortega JA; Castro E; Pena R; Labeaga L; Pazos A; Orjales A
    Psychopharmacology (Berl); 2005 Nov; 182(3):400-13. PubMed ID: 16032410
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evidence for accelerated desensitisation of 5-HT(2C) receptors following combined treatment with fluoxetine and the 5-HT(1A) receptor antagonist, WAY 100,635, in the rat.
    Bristow LJ; O'Connor D; Watts R; Duxon MS; Hutson PH
    Neuropharmacology; 2000 Apr; 39(7):1222-36. PubMed ID: 10760364
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.