286 related articles for article (PubMed ID: 17367809)
1. A conformational switch in the ligand-binding domain regulates the dependence of the glucocorticoid receptor on Hsp90.
Ricketson D; Hostick U; Fang L; Yamamoto KR; Darimont BD
J Mol Biol; 2007 May; 368(3):729-41. PubMed ID: 17367809
[TBL] [Abstract][Full Text] [Related]
2. Unliganded and hormone-bound glucocorticoid receptors interact with distinct hydrophobic sites in the Hsp90 C-terminal domain.
Fang L; Ricketson D; Getubig L; Darimont B
Proc Natl Acad Sci U S A; 2006 Dec; 103(49):18487-92. PubMed ID: 17130446
[TBL] [Abstract][Full Text] [Related]
3. Hsp90 mutants disrupt glucocorticoid receptor ligand binding and destabilize aporeceptor complexes.
Bohen SP
J Biol Chem; 1995 Dec; 270(49):29433-8. PubMed ID: 7493981
[TBL] [Abstract][Full Text] [Related]
4. Mutations at positions 547-553 of rat glucocorticoid receptors reveal that hsp90 binding requires the presence, but not defined composition, of a seven-amino acid sequence at the amino terminus of the ligand binding domain.
Kaul S; Murphy PJ; Chen J; Brown L; Pratt WB; Simons SS
J Biol Chem; 2002 Sep; 277(39):36223-32. PubMed ID: 12145311
[TBL] [Abstract][Full Text] [Related]
5. Assessment of glucocorticoid receptor-heat shock protein 90 interactions in vivo during nucleocytoplasmic trafficking.
Yang J; DeFranco DB
Mol Endocrinol; 1996 Jan; 10(1):3-13. PubMed ID: 8838140
[TBL] [Abstract][Full Text] [Related]
6. Modulation of the Hsp90 chaperone cycle by a stringent client protein.
Lorenz OR; Freiburger L; Rutz DA; Krause M; Zierer BK; Alvira S; Cuéllar J; Valpuesta JM; Madl T; Sattler M; Buchner J
Mol Cell; 2014 Mar; 53(6):941-53. PubMed ID: 24613341
[TBL] [Abstract][Full Text] [Related]
7. Functional analysis of the LXXLL motifs of the human glucocorticoid receptor: association with altered ligand affinity.
Dong DD; Jewell CM; Bienstock RJ; Cidlowski JA
J Steroid Biochem Mol Biol; 2006 Oct; 101(2-3):106-17. PubMed ID: 16914312
[TBL] [Abstract][Full Text] [Related]
8. Steroid-induced conformational changes of rat glucocorticoid receptor cause altered trypsin cleavage of the putative helix 6 in the ligand binding domain.
Xu M; Modarress KJ; Meeker JE; Simons SS
Mol Cell Endocrinol; 1999 Sep; 155(1-2):85-100. PubMed ID: 10580842
[TBL] [Abstract][Full Text] [Related]
9. Chaperoning of glucocorticoid receptors.
Pratt WB; Morishima Y; Murphy M; Harrell M
Handb Exp Pharmacol; 2006; (172):111-38. PubMed ID: 16610357
[TBL] [Abstract][Full Text] [Related]
10. Disruption of the glucocorticoid receptor assembly with heat shock protein 90 by a peptidic antiglucocorticoid.
Dao-Phan HP; Formstecher P; Lefebvre P
Mol Endocrinol; 1997 Jun; 11(7):962-72. PubMed ID: 9178755
[TBL] [Abstract][Full Text] [Related]
11. Helix 8 of the ligand binding domain of the glucocorticoid receptor (GR) is essential for ligand binding.
Deng Q; Waxse B; Riquelme D; Zhang J; Aguilera G
Mol Cell Endocrinol; 2015 Jun; 408():23-32. PubMed ID: 25676569
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of heat shock transcription factor by GR.
Wadekar SA; Li D; Periyasamy S; Sánchez ER
Mol Endocrinol; 2001 Aug; 15(8):1396-410. PubMed ID: 11463862
[TBL] [Abstract][Full Text] [Related]
13. Heat shock protein 90-dependent (geldanamycin-inhibited) movement of the glucocorticoid receptor through the cytoplasm to the nucleus requires intact cytoskeleton.
Galigniana MD; Scruggs JL; Herrington J; Welsh MJ; Carter-Su C; Housley PR; Pratt WB
Mol Endocrinol; 1998 Dec; 12(12):1903-13. PubMed ID: 9849964
[TBL] [Abstract][Full Text] [Related]
14. Regulation of nuclear retention of glucocorticoid receptor by nuclear Hsp90.
Tago K; Tsukahara F; Naruse M; Yoshioka T; Takano K
Mol Cell Endocrinol; 2004 Jan; 213(2):131-8. PubMed ID: 15062560
[TBL] [Abstract][Full Text] [Related]
15. Use of the thiol-specific derivatizing agent N-iodoacetyl-3-[125I]iodotyrosine to demonstrate conformational differences between the unbound and hsp90-bound glucocorticoid receptor hormone binding domain.
Stancato LF; Silverstein AM; Gitler C; Groner B; Pratt WB
J Biol Chem; 1996 Apr; 271(15):8831-6. PubMed ID: 8621522
[TBL] [Abstract][Full Text] [Related]
16. The molecular chaperone Hsp90 can negatively regulate the activity of a glucocorticosteroid-dependent promoter.
Kang KI; Meng X; Devin-Leclerc J; Bouhouche I; Chadli A; Cadepond F; Baulieu EE; Catelli MG
Proc Natl Acad Sci U S A; 1999 Feb; 96(4):1439-44. PubMed ID: 9990042
[TBL] [Abstract][Full Text] [Related]
17. First High-Resolution Crystal Structures of the Glucocorticoid Receptor Ligand-Binding Domain-Peroxisome Proliferator-Activated
Liu X; Wang Y; Ortlund EA
Mol Pharmacol; 2019 Oct; 96(4):408-417. PubMed ID: 31391291
[TBL] [Abstract][Full Text] [Related]
18. A ligand-specific kinetic switch regulates glucocorticoid receptor trafficking and function.
Trebble PJ; Woolven JM; Saunders KA; Simpson KD; Farrow SN; Matthews LC; Ray DW
J Cell Sci; 2013 Jul; 126(Pt 14):3159-69. PubMed ID: 23687373
[TBL] [Abstract][Full Text] [Related]
19. Distinct interaction of cortivazol with the ligand binding domain confers glucocorticoid receptor specificity: cortivazol is a specific ligand for the glucocorticoid receptor.
Yoshikawa N; Makino Y; Okamoto K; Morimoto C; Makino I; Tanaka H
J Biol Chem; 2002 Feb; 277(7):5529-40. PubMed ID: 11741935
[TBL] [Abstract][Full Text] [Related]
20. Biochemical reconstitution of steroid receptor•Hsp90 protein complexes and reactivation of ligand binding.
Murphy PJ; Franklin HR; Furukawa NW
J Vis Exp; 2011 Sep; (55):. PubMed ID: 21968922
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]