These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

119 related articles for article (PubMed ID: 1737018)

  • 41. Circularly permuted interleukin 4 retains proliferative and binding activity.
    Kreitman RJ; Puri RK; McPhie P; Pastan I
    Cytokine; 1995 May; 7(4):311-8. PubMed ID: 8589260
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Investigation of the functional role of tryptophan-22 in Escherichia coli dihydrofolate reductase by site-directed mutagenesis.
    Warren MS; Brown KA; Farnum MF; Howell EE; Kraut J
    Biochemistry; 1991 Nov; 30(46):11092-103. PubMed ID: 1932031
    [TBL] [Abstract][Full Text] [Related]  

  • 43. The kinetic mechanism of wild-type and mutant mouse dihydrofolate reductases.
    Thillet J; Adams JA; Benkovic SJ
    Biochemistry; 1990 May; 29(21):5195-202. PubMed ID: 1974147
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Partial 1H NMR assignments of the Escherichia coli dihydrofolate reductase complex with folate: evidence for a unique conformation of bound folate.
    Falzone CJ; Benkovic SJ; Wright PE
    Biochemistry; 1990 Oct; 29(41):9667-77. PubMed ID: 2271608
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Controlling enzyme inhibition using an expanded set of genetically encoded amino acids.
    Zheng S; Kwon I
    Biotechnol Bioeng; 2013 Sep; 110(9):2361-70. PubMed ID: 23568807
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Transient intermediates in the folding of dihydrofolate reductase as detected by far-ultraviolet circular dichroism spectroscopy.
    Kuwajima K; Garvey EP; Finn BE; Matthews CR; Sugai S
    Biochemistry; 1991 Aug; 30(31):7693-703. PubMed ID: 1868049
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Role of ionic interactions in ligand binding and catalysis of R67 dihydrofolate reductase.
    Hicks SN; Smiley RD; Hamilton JB; Howell EE
    Biochemistry; 2003 Sep; 42(36):10569-78. PubMed ID: 12962480
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Pivotal role of Gly 121 in dihydrofolate reductase from Escherichia coli: the altered structure of a mutant enzyme may form the basis of its diminished catalytic performance.
    Swanwick RS; Shrimpton PJ; Allemann RK
    Biochemistry; 2004 Apr; 43(14):4119-27. PubMed ID: 15065854
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Molecular basis for nonadditive mutational effects in Escherichia coli dihydrofolate reductase.
    Wagner CR; Huang Z; Singleton SF; Benkovic SJ
    Biochemistry; 1995 Dec; 34(48):15671-80. PubMed ID: 7495797
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Identification and cloning of the Mycobacterium avium folA gene, required for dihydrofolate reductase activity.
    Zywno-van Ginkel S; Dooley TP; Suling WJ; Barrow WW
    FEMS Microbiol Lett; 1997 Nov; 156(1):69-78. PubMed ID: 9368362
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Effects of conversion of an invariant tryptophan residue to phenylalanine on the function of human dihydrofolate reductase.
    Huang SM; Delcamp TJ; Tan XH; Smith PL; Prendergast NJ; Freisheim JH
    Biochemistry; 1989 Jan; 28(2):471-8. PubMed ID: 2713326
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Functional role of a mobile loop of Escherichia coli dihydrofolate reductase in transition-state stabilization.
    Li L; Falzone CJ; Wright PE; Benkovic SJ
    Biochemistry; 1992 Sep; 31(34):7826-33. PubMed ID: 1510968
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Sequence perturbation analysis: addressing amino acid indices to elucidate the C-terminal role of Escherichia coli dihydrofolate reductase.
    Takahashi H; Yokota A; Takenawa T; Iwakura M
    J Biochem; 2009 Jun; 145(6):751-62. PubMed ID: 19254927
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Critical role of phenylalanine 34 of human dihydrofolate reductase in substrate and inhibitor binding and in catalysis.
    Nakano T; Spencer HT; Appleman JR; Blakley RL
    Biochemistry; 1994 Aug; 33(33):9945-52. PubMed ID: 8061003
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Intact protein analysis for site-directed mutagenesis overexpression products: plasmid-encoded R67 dihydrofolate reductase.
    VerBerkmoes NC; Strader MB; Smiley RD; Howell EE; Hurst GB; Hettich RL; Stephenson JL
    Anal Biochem; 2002 Jun; 305(1):68-81. PubMed ID: 12018947
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Nonadditive effects of double mutations at the flexible loops, glycine-67 and glycine-121, of Escherichia coli dihydrofolate reductase on its stability and function.
    Ohmae E; Iriyama K; Ichihara S; Gekko K
    J Biochem; 1998 Jan; 123(1):33-41. PubMed ID: 9504406
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Refolding of [6-19F]tryptophan-labeled Escherichia coli dihydrofolate reductase in the presence of ligand: a stopped-flow NMR spectroscopy study.
    Hoeltzli SD; Frieden C
    Biochemistry; 1998 Jan; 37(1):387-98. PubMed ID: 9425060
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Effects of point mutation in a flexible loop on the stability and enzymatic function of Escherichia coli dihydrofolate reductase.
    Gekko K; Yamagami K; Kunori Y; Ichihara S; Kodama M; Iwakura M
    J Biochem; 1993 Jan; 113(1):74-80. PubMed ID: 8454578
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Construction of a fol mutant strain of Escherichia coli for use in dihydrofolate reductase mutagenesis experiments.
    Ahrweiler PM; Frieden C
    J Bacteriol; 1988 Jul; 170(7):3301-4. PubMed ID: 3290203
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Asymmetric mutations in the tetrameric R67 dihydrofolate reductase reveal high tolerance to active-site substitutions.
    Ebert MC; Morley KL; Volpato JP; Schmitzer AR; Pelletier JN
    Protein Sci; 2015 Apr; 24(4):495-507. PubMed ID: 25401264
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.