BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

235 related articles for article (PubMed ID: 1737029)

  • 1. Mutations at the dimer, hexamer, and receptor-binding surfaces of insulin independently affect insulin-insulin and insulin-receptor interactions.
    Shoelson SE; Lu ZX; Parlautan L; Lynch CS; Weiss MA
    Biochemistry; 1992 Feb; 31(6):1757-67. PubMed ID: 1737029
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Heteronuclear 2D NMR studies of an engineered insulin monomer: assignment and characterization of the receptor-binding surface by selective 2H and 13C labeling with application to protein design.
    Weiss MA; Hua QX; Lynch CS; Frank BH; Shoelson SE
    Biochemistry; 1991 Jul; 30(30):7373-89. PubMed ID: 1906742
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nonlocal structural perturbations in a mutant human insulin: sequential resonance assignment and 13C-isotope-aided 2D-NMR studies of [PheB24-->Gly]insulin with implications for receptor recognition.
    Hua QX; Shoelson SE; Weiss MA
    Biochemistry; 1992 Dec; 31(47):11940-51. PubMed ID: 1445924
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Paradoxical structure and function in a mutant human insulin associated with diabetes mellitus.
    Hua QX; Shoelson SE; Inouye K; Weiss MA
    Proc Natl Acad Sci U S A; 1993 Jan; 90(2):582-6. PubMed ID: 8421693
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hierarchical protein "un-design": insulin's intrachain disulfide bridge tethers a recognition alpha-helix.
    Weiss MA; Hua QX; Jia W; Chu YC; Wang RY; Katsoyannis PG
    Biochemistry; 2000 Dec; 39(50):15429-40. PubMed ID: 11112528
    [TBL] [Abstract][Full Text] [Related]  

  • 6. How insulin binds: the B-chain alpha-helix contacts the L1 beta-helix of the insulin receptor.
    Huang K; Xu B; Hu SQ; Chu YC; Hua QX; Qu Y; Li B; Wang S; Wang RY; Nakagawa SH; Theede AM; Whittaker J; De Meyts P; Katsoyannis PG; Weiss MA
    J Mol Biol; 2004 Aug; 341(2):529-50. PubMed ID: 15276842
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Insulin analogs with B24 or B25 phenylalanine replaced by biphenylalanine.
    Du H; Shi J; Cui D; Zhang Y
    Acta Biochim Biophys Sin (Shanghai); 2008 Feb; 40(2):133-9. PubMed ID: 18235975
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystal structure of allo-Ile(A2)-insulin, an inactive chiral analogue: implications for the mechanism of receptor binding.
    Wan ZL; Xu B; Chu YC; Katsoyannis PG; Weiss MA
    Biochemistry; 2003 Nov; 42(44):12770-83. PubMed ID: 14596591
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Two mutant forms of human insulin. Structural consequences of the substitution of invariant B24- or B25-phenylalanine by leucine.
    Wollmer A; Strassburger W; Glatter U; Dodson GG; McCall M; Gattner HG; Danho W; Brandenburg D; Rittel W
    Hoppe Seylers Z Physiol Chem; 1981 Jun; 362(6):581-91. PubMed ID: 7024084
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-function relationships of shortened [LeuB25]insulins, semisynthetic analogues of a mutant human insulin.
    Fischer WH; Saunders D; Brandenburg D; Diaconescu C; Wollmer A; Dodson G; De Meyts P; Zahn H
    Biol Chem Hoppe Seyler; 1986 Sep; 367(9):999-1006. PubMed ID: 3539147
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Semisynthetic insulin analogues modified in positions B24, B25 and B29.
    Svoboda I; Brandenburg D; Barth T; Gattner HG; Jirácek J; Velek J; Bláha I; Ubik K; Kasicka V; Pospísek J
    Biol Chem Hoppe Seyler; 1994 Jun; 375(6):373-8. PubMed ID: 7980868
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Shortened insulin analogues: marked changes in biological activity resulting from replacement of TyrB26 and N-methylation of peptide bonds in the C-terminus of the B-chain.
    Záková L; Barth T; Jirácek J; Barthová J; Zórad S
    Biochemistry; 2004 Mar; 43(8):2323-31. PubMed ID: 14979729
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of the phenylalanine B24 side chain in directing insulin interaction with its receptor. Importance of main chain conformation.
    Mirmira RG; Tager HS
    J Biol Chem; 1989 Apr; 264(11):6349-54. PubMed ID: 2649499
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dynamics of a monomeric insulin analogue: testing the molten-globule hypothesis.
    Hua QX; Ladbury JE; Weiss MA
    Biochemistry; 1993 Feb; 32(6):1433-42. PubMed ID: 8431423
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aromatic anchor at an invariant hormone-receptor interface: function of insulin residue B24 with application to protein design.
    Pandyarajan V; Smith BJ; Phillips NB; Whittaker L; Cox GP; Wickramasinghe N; Menting JG; Wan ZL; Whittaker J; Ismail-Beigi F; Lawrence MC; Weiss MA
    J Biol Chem; 2014 Dec; 289(50):34709-27. PubMed ID: 25305014
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activities of monomeric insulin analogs at position A8 are uncorrelated with their thermodynamic stabilities.
    Weiss MA; Hua QX; Jia W; Nakagawa SH; Chu YC; Hu SQ; Katsoyannis PG
    J Biol Chem; 2001 Oct; 276(43):40018-24. PubMed ID: 11517220
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Diabetes-associated mutations in insulin: consecutive residues in the B chain contact distinct domains of the insulin receptor.
    Xu B; Hu SQ; Chu YC; Huang K; Nakagawa SH; Whittaker J; Katsoyannis PG; Weiss MA
    Biochemistry; 2004 Jul; 43(26):8356-72. PubMed ID: 15222748
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chiral mutagenesis of insulin's hidden receptor-binding surface: structure of an allo-isoleucine(A2) analogue.
    Xu B; Hua QX; Nakagawa SH; Jia W; Chu YC; Katsoyannis PG; Weiss MA
    J Mol Biol; 2002 Feb; 316(3):435-41. PubMed ID: 11866509
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mini-proinsulin and mini-IGF-I: homologous protein sequences encoding non-homologous structures.
    Hua QX; Hu SQ; Jia W; Chu YC; Burke GT; Wang SH; Wang RY; Katsoyannis PG; Weiss MA
    J Mol Biol; 1998 Mar; 277(1):103-18. PubMed ID: 9514738
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Maintenance of the B-chain beta-turn in [GlyB24] insulin mutants: a steady-state fluorescence anisotropy study.
    Pittman I; Nakagawa SH; Tager HS; Steiner DF
    Biochemistry; 1997 Mar; 36(12):3430-7. PubMed ID: 9131992
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.