206 related articles for article (PubMed ID: 17382893)
1. Geldanamycin, an inhibitor of Hsp90 increases cytochrome P450 2E1 mediated toxicity in HepG2 cells through sustained activation of the p38MAPK pathway.
Dey A; Cederbaum AI
Arch Biochem Biophys; 2007 May; 461(2):275-86. PubMed ID: 17382893
[TBL] [Abstract][Full Text] [Related]
2. Geldanamycin, an inhibitor of Hsp90, potentiates cytochrome P4502E1-mediated toxicity in HepG2 cells.
Dey A; Cederbaum AI
J Pharmacol Exp Ther; 2006 Jun; 317(3):1391-9. PubMed ID: 16513847
[TBL] [Abstract][Full Text] [Related]
3. Glutathione depletion in CYP2E1-expressing liver cells induces toxicity due to the activation of p38 mitogen-activated protein kinase and reduction of nuclear factor-kappaB DNA binding activity.
Wu D; Cederbaum A
Mol Pharmacol; 2004 Sep; 66(3):749-60. PubMed ID: 15322268
[TBL] [Abstract][Full Text] [Related]
4. HSP90 inhibitors strengthen extracellular ATP-stimulated synthesis of interleukin-6 in osteoblasts: Amplification of p38 MAP kinase.
Hioki T; Tokuda H; Nakashima D; Fujita K; Kawabata T; Sakai G; Kim W; Tachi J; Tanabe K; Matsushima-Nishiwaki R; Otsuka T; Iida H; Kozawa O
Cell Biochem Funct; 2021 Jan; 39(1):88-97. PubMed ID: 32567086
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK.
Wu D; Cederbaum AI
Redox Biol; 2013; 1(1):552-65. PubMed ID: 24273738
[TBL] [Abstract][Full Text] [Related]
6. Role of p38 MAPK in CYP2E1-dependent arachidonic acid toxicity.
Wu D; Cederbaum AI
J Biol Chem; 2003 Jan; 278(2):1115-24. PubMed ID: 12403788
[TBL] [Abstract][Full Text] [Related]
7. CYP2E1 degradation by in vitro reconstituted systems: role of the molecular chaperone hsp90.
Goasduff T; Cederbaum AI
Arch Biochem Biophys; 2000 Jul; 379(2):321-30. PubMed ID: 10898951
[TBL] [Abstract][Full Text] [Related]
8. HSP90 inhibitors potentiate PGF2α-induced IL-6 synthesis via p38 MAP kinase in osteoblasts.
Fujita K; Tokuda H; Kuroyanagi G; Yamamoto N; Kainuma S; Kawabata T; Sakai G; Matsushima-Nishiwaki R; Kozawa O; Otsuka T
PLoS One; 2017; 12(5):e0177878. PubMed ID: 28542188
[TBL] [Abstract][Full Text] [Related]
9. Geldanamycin, an inhibitor of Hsp90, increases paclitaxel-mediated toxicity in ovarian cancer cells through sustained activation of the p38/H2AX axis.
Mo Q; Zhang Y; Jin X; Gao Y; Wu Y; Hao X; Gao Q; Chen P
Tumour Biol; 2016 Nov; 37(11):14745-14755. PubMed ID: 27629142
[TBL] [Abstract][Full Text] [Related]
10. Increased expression of cytochrome P450 2E1 induces heme oxygenase-1 through ERK MAPK pathway.
Gong P; Cederbaum AI; Nieto N
J Biol Chem; 2003 Aug; 278(32):29693-700. PubMed ID: 12777398
[TBL] [Abstract][Full Text] [Related]
11. Heat shock protein 90 (Hsp90) regulates the stability of transforming growth factor beta-activated kinase 1 (TAK1) in interleukin-1beta-induced cell signaling.
Shi L; Zhang Z; Fang S; Xu J; Liu J; Shen J; Fang F; Luo L; Yin Z
Mol Immunol; 2009 Feb; 46(4):541-50. PubMed ID: 18950863
[TBL] [Abstract][Full Text] [Related]
12. Cisplatin-induced hepatotoxicity is enhanced by elevated expression of cytochrome P450 2E1.
Lu Y; Cederbaum AI
Toxicol Sci; 2006 Feb; 89(2):515-23. PubMed ID: 16251482
[TBL] [Abstract][Full Text] [Related]
13. Nrf2 and antioxidant defense against CYP2E1 toxicity.
Cederbaum AI
Subcell Biochem; 2013; 67():105-30. PubMed ID: 23400918
[TBL] [Abstract][Full Text] [Related]
14. Geldanamycin interferes with the 90-kDa heat shock protein, affecting lipopolysaccharide-mediated interleukin-1 expression and apoptosis within macrophages.
Hsu HY; Wu HL; Tan SK; Li VP; Wang WT; Hsu J; Cheng CH
Mol Pharmacol; 2007 Jan; 71(1):344-56. PubMed ID: 16868182
[TBL] [Abstract][Full Text] [Related]
15. HSP90 inhibitors induce desensitization of EGF receptor via p38 MAPK-mediated phosphorylation at Ser1046/1047 in human pancreatic cancer cells.
Adachi S; Yasuda I; Nakashima M; Yamauchi T; Yamauchi J; Natsume H; Moriwaki H; Kozawa O
Oncol Rep; 2010 Jun; 23(6):1709-14. PubMed ID: 20428829
[TBL] [Abstract][Full Text] [Related]
16. The liver-selective nitric oxide donor O2-vinyl 1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (V-PYRRO/NO) protects HepG2 cells against cytochrome P450 2E1-dependent toxicity.
Gong P; Cederbaum AI; Nieto N
Mol Pharmacol; 2004 Jan; 65(1):130-8. PubMed ID: 14722244
[TBL] [Abstract][Full Text] [Related]
17. Nrf2 and antioxidant defense against CYP2E1 toxicity.
Cederbaum A
Expert Opin Drug Metab Toxicol; 2009 Oct; 5(10):1223-44. PubMed ID: 19671018
[TBL] [Abstract][Full Text] [Related]
18. Heat shock protein 90 maintains the tumour-like character of rheumatoid synovial cells by stabilizing integrin-linked kinase, extracellular signal-regulated kinase and protein kinase B.
Hashiramoto A; Murata M; Kawazoe T; Yoshida K; Akiyama C; Shiozawa K; Shiozawa S
Rheumatology (Oxford); 2011 May; 50(5):852-61. PubMed ID: 21177334
[TBL] [Abstract][Full Text] [Related]
19. Decreased protein and mRNA expression of ER stress proteins GRP78 and GRP94 in HepG2 cells over-expressing CYP2E1.
Dey A; Kessova IG; Cederbaum AI
Arch Biochem Biophys; 2006 Mar; 447(2):155-66. PubMed ID: 16497268
[TBL] [Abstract][Full Text] [Related]
20. Heme oxygenase-1 protects HepG2 cells against cytochrome P450 2E1-dependent toxicity.
Gong P; Cederbaum AI; Nieto N
Free Radic Biol Med; 2004 Feb; 36(3):307-18. PubMed ID: 15036350
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]