These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

90 related articles for article (PubMed ID: 17386254)

  • 1. Learning our ABCs: Rad50 directs MRN repair functions via adenylate kinase activity from the conserved ATP binding cassette.
    Williams RS; Tainer JA
    Mol Cell; 2007 Mar; 25(6):789-91. PubMed ID: 17386254
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rad50 adenylate kinase activity regulates DNA tethering by Mre11/Rad50 complexes.
    Bhaskara V; Dupré A; Lengsfeld B; Hopkins BB; Chan A; Lee JH; Zhang X; Gautier J; Zakian V; Paull TT
    Mol Cell; 2007 Mar; 25(5):647-61. PubMed ID: 17349953
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The rad50 signature motif: essential to ATP binding and biological function.
    Moncalian G; Lengsfeld B; Bhaskara V; Hopfner KP; Karcher A; Alden E; Tainer JA; Paull TT
    J Mol Biol; 2004 Jan; 335(4):937-51. PubMed ID: 14698290
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.
    Williams RS; Williams JS; Tainer JA
    Biochem Cell Biol; 2007 Aug; 85(4):509-20. PubMed ID: 17713585
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of Mre11/Rad50 by Nbs1: effects on nucleotide-dependent DNA binding and association with ataxia-telangiectasia-like disorder mutant complexes.
    Lee JH; Ghirlando R; Bhaskara V; Hoffmeyer MR; Gu J; Paull TT
    J Biol Chem; 2003 Nov; 278(46):45171-81. PubMed ID: 12966088
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Single-Molecule Imaging Reveals How Mre11-Rad50-Nbs1 Initiates DNA Break Repair.
    Myler LR; Gallardo IF; Soniat MM; Deshpande RA; Gonzalez XB; Kim Y; Paull TT; Finkelstein IJ
    Mol Cell; 2017 Sep; 67(5):891-898.e4. PubMed ID: 28867292
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural basis for adenylate kinase activity in ABC ATPases.
    Lammens A; Hopfner KP
    J Mol Biol; 2010 Aug; 401(2):265-73. PubMed ID: 20600125
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Mre11/Rad50/Nbs1 complex: recent insights into catalytic activities and ATP-driven conformational changes.
    Paull TT; Deshpande RA
    Exp Cell Res; 2014 Nov; 329(1):139-47. PubMed ID: 25016281
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.
    Williams GJ; Williams RS; Williams JS; Moncalian G; Arvai AS; Limbo O; Guenther G; SilDas S; Hammel M; Russell P; Tainer JA
    Nat Struct Mol Biol; 2011 Apr; 18(4):423-31. PubMed ID: 21441914
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The characterization of Saccharomyces cerevisiae Mre11/Rad50/Xrs2 complex reveals that Rad50 negatively regulates Mre11 endonucleolytic but not the exonucleolytic activity.
    Ghosal G; Muniyappa K
    J Mol Biol; 2007 Sep; 372(4):864-882. PubMed ID: 17698079
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95.
    Trujillo KM; Yuan SS; Lee EY; Sung P
    J Biol Chem; 1998 Aug; 273(34):21447-50. PubMed ID: 9705271
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lack of MRE11-RAD50-NBS1 (MRN) complex detection occurs frequently in low-grade epithelial ovarian cancer.
    Brandt S; Samartzis EP; Zimmermann AK; Fink D; Moch H; Noske A; Dedes KJ
    BMC Cancer; 2017 Jan; 17(1):44. PubMed ID: 28073364
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Mre11:Rad50 structure shows an ATP-dependent molecular clamp in DNA double-strand break repair.
    Lammens K; Bemeleit DJ; Möckel C; Clausing E; Schele A; Hartung S; Schiller CB; Lucas M; Angermüller C; Söding J; Strässer K; Hopfner KP
    Cell; 2011 Apr; 145(1):54-66. PubMed ID: 21458667
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex.
    Lee KY; Im JS; Shibata E; Park J; Handa N; Kowalczykowski SC; Dutta A
    Nat Commun; 2015 Jul; 6():7744. PubMed ID: 26215093
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase.
    Hopfner KP; Karcher A; Craig L; Woo TT; Carney JP; Tainer JA
    Cell; 2001 May; 105(4):473-85. PubMed ID: 11371344
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair.
    Lafrance-Vanasse J; Williams GJ; Tainer JA
    Prog Biophys Mol Biol; 2015 Mar; 117(2-3):182-193. PubMed ID: 25576492
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sae2 promotes DNA damage resistance by removing the Mre11-Rad50-Xrs2 complex from DNA and attenuating Rad53 signaling.
    Chen H; Donnianni RA; Handa N; Deng SK; Oh J; Timashev LA; Kowalczykowski SC; Symington LS
    Proc Natl Acad Sci U S A; 2015 Apr; 112(15):E1880-7. PubMed ID: 25831494
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Arsenic-induced Mre11 phosphorylation is cell cycle-dependent and defective in NBS cells.
    Yuan SS; Su JH; Hou MF; Yang FW; Zhao S; Lee EY
    DNA Repair (Amst); 2002 Feb; 1(2):137-42. PubMed ID: 12509260
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A nanomachine for making ends meet: MRN is a flexing scaffold for the repair of DNA double-strand breaks.
    Williams RS; Tainer JA
    Mol Cell; 2005 Sep; 19(6):724-6. PubMed ID: 16168369
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Relocalization of the Mre11-Rad50-Nbs1 complex by the adenovirus E4 ORF3 protein is required for viral replication.
    Evans JD; Hearing P
    J Virol; 2005 May; 79(10):6207-15. PubMed ID: 15858005
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.