BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

224 related articles for article (PubMed ID: 1738847)

  • 1. Processing of the amyloid protein precursor to potentially amyloidogenic derivatives.
    Golde TE; Estus S; Younkin LH; Selkoe DJ; Younkin SG
    Science; 1992 Feb; 255(5045):728-30. PubMed ID: 1738847
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Potentially amyloidogenic, carboxyl-terminal derivatives of the amyloid protein precursor.
    Estus S; Golde TE; Kunishita T; Blades D; Lowery D; Eisen M; Usiak M; Qu XM; Tabira T; Greenberg BD
    Science; 1992 Feb; 255(5045):726-8. PubMed ID: 1738846
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intracellular generation of amyloid beta-protein from amyloid beta-protein precursor fragment by direct cleavage with beta- and gamma-secretase.
    Iizuka T; Shoji M; Kawarabayashi T; Sato M; Kobayashi T; Tada N; Kasai K; Matsubara E; Watanabe M; Tomidokoro Y; Hirai S
    Biochem Biophys Res Commun; 1996 Jan; 218(1):238-42. PubMed ID: 8573139
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential regulation of amyloid precursor protein sorting with pathological mutations results in a distinct effect on amyloid-β production.
    Lin YC; Wang JY; Wang KC; Liao JY; Cheng IH
    J Neurochem; 2014 Nov; 131(4):407-12. PubMed ID: 25053581
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Normal cellular processing of the beta-amyloid precursor protein results in the secretion of the amyloid beta peptide and related molecules.
    Haass C; Hung AY; Schlossmacher MG; Oltersdorf T; Teplow DB; Selkoe DJ
    Ann N Y Acad Sci; 1993 Sep; 695():109-16. PubMed ID: 8239267
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The expression and processing of human beta-amyloid peptide precursors in Saccharomyces cerevisiae: evidence for a novel endopeptidase in the yeast secretory system.
    Hines V; Zhang W; Ramakrishna N; Styles J; Mehta P; Kim KS; Innis M; Miller DL
    Cell Mol Biol Res; 1994; 40(4):273-84. PubMed ID: 7866429
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Potentially amyloidogenic fragment of 50 kDa and intracellular processing of amyloid precursor protein in cells cultured under leupeptin.
    Tsuzuki K; Fukatsu R; Takamaru Y; Fujii N; Takahata N
    Brain Res; 1994 Oct; 659(1-2):213-20. PubMed ID: 7820664
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Truncated carboxyl-terminal fragments of beta-amyloid precursor protein are processed to amyloid beta-proteins 40 and 42.
    Funamoto S; Morishima-Kawashima M; Tanimura Y; Hirotani N; Saido TC; Ihara Y
    Biochemistry; 2004 Oct; 43(42):13532-40. PubMed ID: 15491160
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The nature and metabolism of potentially amyloidogenic carboxyl-terminal fragments of the Alzheimer beta/A4-amyloid precursor protein: some technical notes.
    Gandy SE; Buxbaum JD; Suzuki T; Ramabhadran TV; Caporaso GL; Nairn AC; Greengard P
    Neurobiol Aging; 1992; 13(5):601-3. PubMed ID: 1461349
    [TBL] [Abstract][Full Text] [Related]  

  • 10. beta-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms.
    Haass C; Hung AY; Schlossmacher MG; Teplow DB; Selkoe DJ
    J Biol Chem; 1993 Feb; 268(5):3021-4. PubMed ID: 8428976
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Processing of the beta-amyloid precursor. Multiple proteases generate and degrade potentially amyloidogenic fragments.
    Siman R; Mistretta S; Durkin JT; Savage MJ; Loh T; Trusko S; Scott RW
    J Biol Chem; 1993 Aug; 268(22):16602-9. PubMed ID: 8344942
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Polarized sorting of beta-amyloid precursor protein and its proteolytic products in MDCK cells is regulated by two independent signals.
    Haass C; Koo EH; Capell A; Teplow DB; Selkoe DJ
    J Cell Biol; 1995 Feb; 128(4):537-47. PubMed ID: 7860629
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Proteolytic processing of human amyloid beta protein precursor in insect cells. Major carboxyl-terminal fragment is identical to its human counterpart.
    Ramabhadran TV; Gandy SE; Ghiso J; Czernik AJ; Ferris D; Bhasin R; Goldgaber D; Frangione B; Greengard P
    J Biol Chem; 1993 Jan; 268(3):2009-12. PubMed ID: 8420974
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.
    Haass C; Koo EH; Mellon A; Hung AY; Selkoe DJ
    Nature; 1992 Jun; 357(6378):500-3. PubMed ID: 1608449
    [TBL] [Abstract][Full Text] [Related]  

  • 15. beta-Amyloid precursor protein fragments and lysosomal dense bodies are found in rat brain neurons after ventricular infusion of leupeptin.
    Hajimohammadreza I; Anderson VE; Cavanagh JB; Seville MP; Nolan CC; Anderton BH; Leigh PN
    Brain Res; 1994 Mar; 640(1-2):25-32. PubMed ID: 8004453
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evidence for a nonsecretory, acidic degradation pathway for amyloid precursor protein in 293 cells. Identification of a novel, 22-kDa, beta-peptide-containing intermediate.
    Knops J; Lieberburg I; Sinha S
    J Biol Chem; 1992 Aug; 267(23):16022-4. PubMed ID: 1644790
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Alzheimer beta/A4-amyloid precursor protein: evidence for putative amyloidogenic fragment.
    Gandy SE; Bhasin R; Ramabhadran TV; Koo EH; Price DL; Goldgaber D; Greengard P
    J Neurochem; 1992 Jan; 58(1):383-6. PubMed ID: 1345769
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of beta-amyloid peptide precursor processing by the yeast Yap3 and Mkc7 proteases.
    Zhang W; Espinoza D; Hines V; Innis M; Mehta P; Miller DL
    Biochim Biophys Acta; 1997 Nov; 1359(2):110-22. PubMed ID: 9409808
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Alzheimer beta-amyloid protein precursor/protease nexin-II is cleaved by secretase in a trans-Golgi secretory compartment in human neuroglioma cells.
    Kuentzel SL; Ali SM; Altman RA; Greenberg BD; Raub TJ
    Biochem J; 1993 Oct; 295 ( Pt 2)(Pt 2):367-78. PubMed ID: 8240235
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease beta-amyloid protein precursor: effect of C-terminal truncation on production of beta-amyloid protein.
    Nunan J; Williamson NA; Hill AF; Sernee MF; Masters CL; Small DH
    J Neurosci Res; 2003 Nov; 74(3):378-85. PubMed ID: 14598314
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.