BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

467 related articles for article (PubMed ID: 17389404)

  • 1. Structural insights into the degradation of Mcl-1 induced by BH3 domains.
    Czabotar PE; Lee EF; van Delft MF; Day CL; Smith BJ; Huang DC; Fairlie WD; Hinds MG; Colman PM
    Proc Natl Acad Sci U S A; 2007 Apr; 104(15):6217-22. PubMed ID: 17389404
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation.
    Lee EF; Czabotar PE; van Delft MF; Michalak EM; Boyle MJ; Willis SN; Puthalakath H; Bouillet P; Colman PM; Huang DC; Fairlie WD
    J Cell Biol; 2008 Jan; 180(2):341-55. PubMed ID: 18209102
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure of the BH3 domains from the p53-inducible BH3-only proteins Noxa and Puma in complex with Mcl-1.
    Day CL; Smits C; Fan FC; Lee EF; Fairlie WD; Hinds MG
    J Mol Biol; 2008 Jul; 380(5):958-71. PubMed ID: 18589438
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function.
    Chen L; Willis SN; Wei A; Smith BJ; Fletcher JI; Hinds MG; Colman PM; Day CL; Adams JM; Huang DC
    Mol Cell; 2005 Feb; 17(3):393-403. PubMed ID: 15694340
    [TBL] [Abstract][Full Text] [Related]  

  • 5. BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly.
    Kuwana T; Bouchier-Hayes L; Chipuk JE; Bonzon C; Sullivan BA; Green DR; Newmeyer DD
    Mol Cell; 2005 Feb; 17(4):525-35. PubMed ID: 15721256
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Solution structure of prosurvival Mcl-1 and characterization of its binding by proapoptotic BH3-only ligands.
    Day CL; Chen L; Richardson SJ; Harrison PJ; Huang DC; Hinds MG
    J Biol Chem; 2005 Feb; 280(6):4738-44. PubMed ID: 15550399
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Noxa up-regulation and Mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma.
    Gomez-Bougie P; Wuillème-Toumi S; Ménoret E; Trichet V; Robillard N; Philippe M; Bataille R; Amiot M
    Cancer Res; 2007 Jun; 67(11):5418-24. PubMed ID: 17545623
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Selective involvement of BH3-only proteins and differential targets of Noxa in diverse apoptotic pathways.
    Zhang L; Lopez H; George NM; Liu X; Pang X; Luo X
    Cell Death Differ; 2011 May; 18(5):864-73. PubMed ID: 21113147
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Emerging role of Mcl-1 in actively counteracting BH3-only proteins in apoptosis.
    Zhuang J; Brady HJ
    Cell Death Differ; 2006 Aug; 13(8):1263-7. PubMed ID: 16676002
    [No Abstract]   [Full Text] [Related]  

  • 10. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.
    Kim H; Rafiuddin-Shah M; Tu HC; Jeffers JR; Zambetti GP; Hsieh JJ; Cheng EH
    Nat Cell Biol; 2006 Dec; 8(12):1348-58. PubMed ID: 17115033
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes.
    Fire E; Gullá SV; Grant RA; Keating AE
    Protein Sci; 2010 Mar; 19(3):507-19. PubMed ID: 20066663
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.
    Willis SN; Chen L; Dewson G; Wei A; Naik E; Fletcher JI; Adams JM; Huang DC
    Genes Dev; 2005 Jun; 19(11):1294-305. PubMed ID: 15901672
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular dynamics study of segment peptides of Bax, Bim, and Mcl-1 BH3 domain of the apoptosis-regulating proteins bound to the anti-apoptotic Mcl-1 protein.
    Zhao RN; Fan S; Han JG; Liu G
    J Biomol Struct Dyn; 2015; 33(5):1067-81. PubMed ID: 24865469
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential interactions between Beclin 1 and Bcl-2 family members.
    Erlich S; Mizrachy L; Segev O; Lindenboim L; Zmira O; Adi-Harel S; Hirsch JA; Stein R; Pinkas-Kramarski R
    Autophagy; 2007; 3(6):561-8. PubMed ID: 17643073
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Crosstalk among Bcl-2 family members in B-CLL: seliciclib acts via the Mcl-1/Noxa axis and gradual exhaustion of Bcl-2 protection.
    Hallaert DY; Spijker R; Jak M; Derks IA; Alves NL; Wensveen FM; de Boer JP; de Jong D; Green SR; van Oers MH; Eldering E
    Cell Death Differ; 2007 Nov; 14(11):1958-67. PubMed ID: 17703234
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis.
    Herrant M; Jacquel A; Marchetti S; Belhacène N; Colosetti P; Luciano F; Auberger P
    Oncogene; 2004 Oct; 23(47):7863-73. PubMed ID: 15378010
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Puma(*)Mcl-1 interaction is not sufficient to prevent rapid degradation of Mcl-1.
    Mei Y; Du W; Yang Y; Wu M
    Oncogene; 2005 Nov; 24(48):7224-37. PubMed ID: 16007132
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mouse Noxa uses only the C-terminal BH3-domain to inactivate Mcl-1.
    Weber A; Ausländer D; Häcker G
    Apoptosis; 2013 Sep; 18(9):1093-105. PubMed ID: 23733106
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A novel BH3 mimetic efficiently induces apoptosis in melanoma cells through direct binding to anti-apoptotic Bcl-2 family proteins, including phosphorylated Mcl-1.
    Liu Y; Xie M; Song T; Sheng H; Yu X; Zhang Z
    Pigment Cell Melanoma Res; 2015 Mar; 28(2):161-70. PubMed ID: 25324174
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluation of diverse α/β-backbone patterns for functional α-helix mimicry: analogues of the Bim BH3 domain.
    Boersma MD; Haase HS; Peterson-Kaufman KJ; Lee EF; Clarke OB; Colman PM; Smith BJ; Horne WS; Fairlie WD; Gellman SH
    J Am Chem Soc; 2012 Jan; 134(1):315-23. PubMed ID: 22040025
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.