BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

465 related articles for article (PubMed ID: 17393136)

  • 1. Pancreatic deletion of insulin receptor substrate 2 reduces beta and alpha cell mass and impairs glucose homeostasis in mice.
    Cantley J; Choudhury AI; Asare-Anane H; Selman C; Lingard S; Heffron H; Herrera P; Persaud SJ; Withers DJ
    Diabetologia; 2007 Jun; 50(6):1248-56. PubMed ID: 17393136
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice.
    da Silva Xavier G; Mondragon A; Sun G; Chen L; McGinty JA; French PM; Rutter GA
    Diabetologia; 2012 Oct; 55(10):2667-2676. PubMed ID: 22717537
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Liver-specific deletion of insulin receptor substrate 2 does not impair hepatic glucose and lipid metabolism in mice.
    Simmgen M; Knauf C; Lopez M; Choudhury AI; Charalambous M; Cantley J; Bedford DC; Claret M; Iglesias MA; Heffron H; Cani PD; Vidal-Puig A; Burcelin R; Withers DJ
    Diabetologia; 2006 Mar; 49(3):552-61. PubMed ID: 16404553
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of insulin receptor substrate 2 in hypothalamic and beta cell function.
    Choudhury AI; Heffron H; Smith MA; Al-Qassab H; Xu AW; Selman C; Simmgen M; Clements M; Claret M; Maccoll G; Bedford DC; Hisadome K; Diakonov I; Moosajee V; Bell JD; Speakman JR; Batterham RL; Barsh GS; Ashford ML; Withers DJ
    J Clin Invest; 2005 Apr; 115(4):940-50. PubMed ID: 15841180
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SIRT6-mediated transcriptional suppression of Txnip is critical for pancreatic beta cell function and survival in mice.
    Qin K; Zhang N; Zhang Z; Nipper M; Zhu Z; Leighton J; Xu K; Musi N; Wang P
    Diabetologia; 2018 Apr; 61(4):906-918. PubMed ID: 29322219
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Receptors for insulin and insulin-like growth factor-1 and insulin receptor substrate-1 mediate pathways that regulate islet function.
    Kulkarni RN
    Biochem Soc Trans; 2002 Apr; 30(2):317-22. PubMed ID: 12023872
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TCF7L2 in mouse pancreatic beta cells plays a crucial role in glucose homeostasis by regulating beta cell mass.
    Takamoto I; Kubota N; Nakaya K; Kumagai K; Hashimoto S; Kubota T; Inoue M; Kajiwara E; Katsuyama H; Obata A; Sakurai Y; Iwamoto M; Kitamura T; Ueki K; Kadowaki T
    Diabetologia; 2014 Mar; 57(3):542-53. PubMed ID: 24317852
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Alterations of pancreatic beta-cell mass and islet number due to Ins2-controlled expression of Cre recombinase: RIP-Cre revisited; part 2.
    Pomplun D; Florian S; Schulz T; Pfeiffer AF; Ristow M
    Horm Metab Res; 2007 May; 39(5):336-40. PubMed ID: 17533574
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Retinoic acid receptor signaling is required to maintain glucose-stimulated insulin secretion and β-cell mass.
    Brun PJ; Grijalva A; Rausch R; Watson E; Yuen JJ; Das BC; Shudo K; Kagechika H; Leibel RL; Blaner WS
    FASEB J; 2015 Feb; 29(2):671-83. PubMed ID: 25389133
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Exendin-4 uses Irs2 signaling to mediate pancreatic beta cell growth and function.
    Park S; Dong X; Fisher TL; Dunn S; Omer AK; Weir G; White MF
    J Biol Chem; 2006 Jan; 281(2):1159-68. PubMed ID: 16272563
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus.
    Kubota N; Terauchi Y; Tobe K; Yano W; Suzuki R; Ueki K; Takamoto I; Satoh H; Maki T; Kubota T; Moroi M; Okada-Iwabu M; Ezaki O; Nagai R; Ueta Y; Kadowaki T; Noda T
    J Clin Invest; 2004 Oct; 114(7):917-27. PubMed ID: 15467830
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice.
    Bao S; Jacobson DA; Wohltmann M; Bohrer A; Jin W; Philipson LH; Turk J
    Am J Physiol Endocrinol Metab; 2008 Feb; 294(2):E217-29. PubMed ID: 17895289
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Islet secretory defect in insulin receptor substrate 1 null mice is linked with reduced calcium signaling and expression of sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA)-2b and -3.
    Kulkarni RN; Roper MG; Dahlgren G; Shih DQ; Kauri LM; Peters JL; Stoffel M; Kennedy RT
    Diabetes; 2004 Jun; 53(6):1517-25. PubMed ID: 15161756
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pancreatic, but not myeloid-cell, expression of interleukin-1alpha is required for maintenance of insulin secretion and whole body glucose homeostasis.
    Collier JJ; Batdorf HM; Martin TM; Rohli KE; Burk DH; Lu D; Cooley CR; Karlstad MD; Jackson JW; Sparer TE; Zhang J; Mynatt RL; Burke SJ
    Mol Metab; 2021 Feb; 44():101140. PubMed ID: 33285301
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Essential role of chicken ovalbumin upstream promoter-transcription factor II in insulin secretion and insulin sensitivity revealed by conditional gene knockout.
    Bardoux P; Zhang P; Flamez D; Perilhou A; Lavin TA; Tanti JF; Hellemans K; Gomas E; Godard C; Andreelli F; Buccheri MA; Kahn A; Le Marchand-Brustel Y; Burcelin R; Schuit F; Vasseur-Cognet M
    Diabetes; 2005 May; 54(5):1357-63. PubMed ID: 15855320
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phosphatase and tensin homolog regulation of islet growth and glucose homeostasis.
    Kushner JA; Simpson L; Wartschow LM; Guo S; Rankin MM; Parsons R; White MF
    J Biol Chem; 2005 Nov; 280(47):39388-93. PubMed ID: 16170201
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes.
    Lin X; Taguchi A; Park S; Kushner JA; Li F; Li Y; White MF
    J Clin Invest; 2004 Oct; 114(7):908-16. PubMed ID: 15467829
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Beta-cell-specific ablation of the hepatocyte growth factor receptor results in reduced islet size, impaired insulin secretion, and glucose intolerance.
    Dai C; Huh CG; Thorgeirsson SS; Liu Y
    Am J Pathol; 2005 Aug; 167(2):429-36. PubMed ID: 16049329
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pdx1 restores beta cell function in Irs2 knockout mice.
    Kushner JA; Ye J; Schubert M; Burks DJ; Dow MA; Flint CL; Dutta S; Wright CV; Montminy MR; White MF
    J Clin Invest; 2002 May; 109(9):1193-201. PubMed ID: 11994408
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transgenic mice expressing Shb adaptor protein under the control of rat insulin promoter exhibit altered viability of pancreatic islet cells.
    Welsh M; Christmansson L; Karlsson T; Sandler S; Welsh N
    Mol Med; 1999 Mar; 5(3):169-80. PubMed ID: 10404514
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.