BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

334 related articles for article (PubMed ID: 17403773)

  • 1. NBK/BIK antagonizes MCL-1 and BCL-XL and activates BAK-mediated apoptosis in response to protein synthesis inhibition.
    Shimazu T; Degenhardt K; Nur-E-Kamal A; Zhang J; Yoshida T; Zhang Y; Mathew R; White E; Inouye M
    Genes Dev; 2007 Apr; 21(8):929-41. PubMed ID: 17403773
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis.
    Gillissen B; Essmann F; Hemmati PG; Richter A; Richter A; Oztop I; Chinnadurai G; Dörken B; Daniel PT
    J Cell Biol; 2007 Nov; 179(4):701-15. PubMed ID: 18025305
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Caspase-independent induction of apoptosis in human melanoma cells by the proapoptotic Bcl-2-related protein Nbk / Bik.
    Oppermann M; Geilen CC; Fecker LF; Gillissen B; Daniel PT; Eberle J
    Oncogene; 2005 Nov; 24(49):7369-80. PubMed ID: 16007125
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.
    Kim H; Rafiuddin-Shah M; Tu HC; Jeffers JR; Zambetti GP; Hsieh JJ; Cheng EH
    Nat Cell Biol; 2006 Dec; 8(12):1348-58. PubMed ID: 17115033
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells.
    Sung ES; Park KJ; Choi HJ; Kim CH; Kim YS
    Exp Cell Res; 2012 Aug; 318(13):1564-76. PubMed ID: 22513214
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway.
    Gillissen B; Essmann F; Graupner V; Stärck L; Radetzki S; Dörken B; Schulze-Osthoff K; Daniel PT
    EMBO J; 2003 Jul; 22(14):3580-90. PubMed ID: 12853473
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evidence for involvement of BH3-only proapoptotic members in adenovirus-induced apoptosis.
    Subramanian T; Vijayalingam S; Lomonosova E; Zhao LJ; Chinnadurai G
    J Virol; 2007 Oct; 81(19):10486-95. PubMed ID: 17652400
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.
    Willis SN; Chen L; Dewson G; Wei A; Naik E; Fletcher JI; Adams JM; Huang DC
    Genes Dev; 2005 Jun; 19(11):1294-305. PubMed ID: 15901672
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In non-transformed cells Bak activates upon loss of anti-apoptotic Bcl-XL and Mcl-1 but in the absence of active BH3-only proteins.
    Senft D; Weber A; Saathoff F; Berking C; Heppt MV; Kammerbauer C; Rothenfusser S; Kellner S; Kurgyis Z; Besch R; Häcker G
    Cell Death Dis; 2015 Nov; 6(11):e1996. PubMed ID: 26610208
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The apoptosis promoting Bcl-2 homologues Bak and Nbk/Bik overcome drug resistance in Mdr-1-negative and Mdr-1-overexpressing breast cancer cell lines.
    Radetzki S; Köhne CH; von Haefen C; Gillissen B; Sturm I; Dörken B; Daniel PT
    Oncogene; 2002 Jan; 21(2):227-38. PubMed ID: 11803466
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak.
    Willis SN; Fletcher JI; Kaufmann T; van Delft MF; Chen L; Czabotar PE; Ierino H; Lee EF; Fairlie WD; Bouillet P; Strasser A; Kluck RM; Adams JM; Huang DC
    Science; 2007 Feb; 315(5813):856-9. PubMed ID: 17289999
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BH3-only proteins Noxa, Bik, Bmf, and Bid activate Bax and Bak indirectly when studied in yeast model.
    Gérecová G; Kopanicová J; Jaká P; Běhalová L; Juhásová B; Bhatia-Kiššová I; Forte M; Polčic P; Mentel M
    FEMS Yeast Res; 2013 Dec; 13(8):747-54. PubMed ID: 23991648
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax.
    Hockings C; Anwari K; Ninnis RL; Brouwer J; O'Hely M; Evangelista M; Hinds MG; Czabotar PE; Lee EF; Fairlie WD; Dewson G; Kluck RM
    Cell Death Dis; 2015 Apr; 6(4):e1735. PubMed ID: 25906158
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane.
    O'Neill KL; Huang K; Zhang J; Chen Y; Luo X
    Genes Dev; 2016 Apr; 30(8):973-88. PubMed ID: 27056669
    [TBL] [Abstract][Full Text] [Related]  

  • 15. p14(ARF)-induced apoptosis in p53 protein-deficient cells is mediated by BH3-only protein-independent derepression of Bak protein through down-regulation of Mcl-1 and Bcl-xL proteins.
    Müer A; Overkamp T; Gillissen B; Richter A; Pretzsch T; Milojkovic A; Dörken B; Daniel PT; Hemmati P
    J Biol Chem; 2012 May; 287(21):17343-17352. PubMed ID: 22354970
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mcl-1 and Bcl-x
    Hockings C; Alsop AE; Fennell SC; Lee EF; Fairlie WD; Dewson G; Kluck RM
    Cell Death Differ; 2018 Mar; 25(4):721-734. PubMed ID: 29459767
    [TBL] [Abstract][Full Text] [Related]  

  • 17. BH3-only proteins target BCL-xL/MCL-1, not BAX/BAK, to initiate apoptosis.
    Huang K; O'Neill KL; Li J; Zhou W; Han N; Pang X; Wu W; Struble L; Borgstahl G; Liu Z; Zhang L; Luo X
    Cell Res; 2019 Nov; 29(11):942-952. PubMed ID: 31551537
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synergistic induction of apoptosis by p53-inducible Bcl-2 family proteins Noxa and Puma.
    Nakajima W; Tanaka N
    J Nippon Med Sch; 2007 Apr; 74(2):148-57. PubMed ID: 17507791
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Noxa induces apoptosis in oncogene-expressing cells through catch-and-release mechanism operating between Puma and Mcl-1.
    Nakajima W; Tanaka N
    Biochem Biophys Res Commun; 2011 Oct; 413(4):643-8. PubMed ID: 21945433
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Induction and endoplasmic reticulum location of BIK/NBK in response to apoptotic signaling by E1A and p53.
    Mathai JP; Germain M; Marcellus RC; Shore GC
    Oncogene; 2002 Apr; 21(16):2534-44. PubMed ID: 11971188
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.