231 related articles for article (PubMed ID: 17418408)
1. Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway.
Pollard PJ; Spencer-Dene B; Shukla D; Howarth K; Nye E; El-Bahrawy M; Deheragoda M; Joannou M; McDonald S; Martin A; Igarashi P; Varsani-Brown S; Rosewell I; Poulsom R; Maxwell P; Stamp GW; Tomlinson IP
Cancer Cell; 2007 Apr; 11(4):311-9. PubMed ID: 17418408
[TBL] [Abstract][Full Text] [Related]
2. Fumarate hydratase deficiency and cancer: activation of hypoxia signaling?
Ratcliffe PJ
Cancer Cell; 2007 Apr; 11(4):303-5. PubMed ID: 17418405
[TBL] [Abstract][Full Text] [Related]
3. Expression profiling in progressive stages of fumarate-hydratase deficiency: the contribution of metabolic changes to tumorigenesis.
Ashrafian H; O'Flaherty L; Adam J; Steeples V; Chung YL; East P; Vanharanta S; Lehtonen H; Nye E; Hatipoglu E; Miranda M; Howarth K; Shukla D; Troy H; Griffiths J; Spencer-Dene B; Yusuf M; Volpi E; Maxwell PH; Stamp G; Poulsom R; Pugh CW; Costa B; Bardella C; Di Renzo MF; Kotlikoff MI; Launonen V; Aaltonen L; El-Bahrawy M; Tomlinson I; Pollard PJ
Cancer Res; 2010 Nov; 70(22):9153-65. PubMed ID: 20978192
[TBL] [Abstract][Full Text] [Related]
4. Over expression of hypoxia-inducible protein 2, hypoxia-inducible factor-1alpha and nuclear factor kappaB is putatively involved in acquired renal cyst formation and subsequent tumor transformation in patients with end stage renal failure.
Konda R; Sugimura J; Sohma F; Katagiri T; Nakamura Y; Fujioka T
J Urol; 2008 Aug; 180(2):481-5. PubMed ID: 18550099
[TBL] [Abstract][Full Text] [Related]
5. Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations.
Pollard PJ; Brière JJ; Alam NA; Barwell J; Barclay E; Wortham NC; Hunt T; Mitchell M; Olpin S; Moat SJ; Hargreaves IP; Heales SJ; Chung YL; Griffiths JR; Dalgleish A; McGrath JA; Gleeson MJ; Hodgson SV; Poulsom R; Rustin P; Tomlinson IP
Hum Mol Genet; 2005 Aug; 14(15):2231-9. PubMed ID: 15987702
[TBL] [Abstract][Full Text] [Related]
6. The hypoxia-inducible factor 2alpha N-terminal and C-terminal transactivation domains cooperate to promote renal tumorigenesis in vivo.
Yan Q; Bartz S; Mao M; Li L; Kaelin WG
Mol Cell Biol; 2007 Mar; 27(6):2092-102. PubMed ID: 17220275
[TBL] [Abstract][Full Text] [Related]
7. Kidney development and gene expression in the HIF2alpha knockout mouse.
Steenhard BM; Freeburg PB; Isom K; Stroganova L; Borza DB; Hudson BG; St John PL; Zelenchuk A; Abrahamson DR
Dev Dyn; 2007 Apr; 236(4):1115-25. PubMed ID: 17342756
[TBL] [Abstract][Full Text] [Related]
8. Evidence of increased microvessel density and activation of the hypoxia pathway in tumours from the hereditary leiomyomatosis and renal cell cancer syndrome.
Pollard P; Wortham N; Barclay E; Alam A; Elia G; Manek S; Poulsom R; Tomlinson I
J Pathol; 2005 Jan; 205(1):41-9. PubMed ID: 15586379
[TBL] [Abstract][Full Text] [Related]
9. HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability.
Isaacs JS; Jung YJ; Mole DR; Lee S; Torres-Cabala C; Chung YL; Merino M; Trepel J; Zbar B; Toro J; Ratcliffe PJ; Linehan WM; Neckers L
Cancer Cell; 2005 Aug; 8(2):143-53. PubMed ID: 16098467
[TBL] [Abstract][Full Text] [Related]
10. Immunohistochemical expression of hypoxia inducible factor-1alpha and its downstream molecules in sarcomatoid renal cell carcinoma.
Tickoo SK; Alden D; Olgac S; Fine SW; Russo P; Kondagunta GV; Motzer RJ; Reuter VE
J Urol; 2007 Apr; 177(4):1258-63. PubMed ID: 17382701
[TBL] [Abstract][Full Text] [Related]
11. Effect of endothelial PAS domain protein 1 and hypoxia inducible factor 1alpha on vascular endothelial growth factor expression in human pancreatic carcinoma.
Zhu DM; Li DC; Zhang ZX; Zhang XY
Chin Med J (Engl); 2008 Nov; 121(22):2258-64. PubMed ID: 19080330
[TBL] [Abstract][Full Text] [Related]
12. Glucose transporter-1 expression in renal cell carcinoma and its correlation with hypoxia inducible factor-1 alpha.
Lidgren A; Bergh A; Grankvist K; Rasmuson T; Ljungberg B
BJU Int; 2008 Feb; 101(4):480-4. PubMed ID: 17922867
[TBL] [Abstract][Full Text] [Related]
13. Short-term effects of pharmacologic HIF stabilization on vasoactive and cytotrophic factors in developing mouse brain.
Schneider C; Krischke G; Keller S; Walkinshaw G; Arend M; Rascher W; Gassmann M; Trollmann R
Brain Res; 2009 Jul; 1280():43-51. PubMed ID: 19450570
[TBL] [Abstract][Full Text] [Related]
14. Cells lacking the fumarase tumor suppressor are protected from apoptosis through a hypoxia-inducible factor-independent, AMPK-dependent mechanism.
Bardella C; Olivero M; Lorenzato A; Geuna M; Adam J; O'Flaherty L; Rustin P; Tomlinson I; Pollard PJ; Di Renzo MF
Mol Cell Biol; 2012 Aug; 32(15):3081-94. PubMed ID: 22645311
[TBL] [Abstract][Full Text] [Related]
15. Phosphorylated VEGFR2/KDR receptors are widely expressed in B-cell non-Hodgkin's lymphomas and correlate with hypoxia inducible factor activation.
Giatromanolaki A; Koukourakis MI; Pezzella F; Sivridis E; Turley H; Harris AL; Gatter KC
Hematol Oncol; 2008 Dec; 26(4):219-24. PubMed ID: 18461646
[TBL] [Abstract][Full Text] [Related]
16. Basic-helix-loop-helix (bHLH) transcription factor DEC2 negatively regulates vascular endothelial growth factor expression.
Sato F; Bhawal UK; Kawamoto T; Fujimoto K; Imaizumi T; Imanaka T; Kondo J; Koyanagi S; Noshiro M; Yoshida H; Kusumi T; Kato Y; Kijima H
Genes Cells; 2008 Feb; 13(2):131-44. PubMed ID: 18233956
[TBL] [Abstract][Full Text] [Related]
17. Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia.
Chen J; Futami K; Petillo D; Peng J; Wang P; Knol J; Li Y; Khoo SK; Huang D; Qian CN; Zhao P; Dykema K; Zhang R; Cao B; Yang XJ; Furge K; Williams BO; Teh BT
PLoS One; 2008; 3(10):e3581. PubMed ID: 18974783
[TBL] [Abstract][Full Text] [Related]
18. Hypoxia-inducible factor is expressed in giant cell tumour of bone and mediates paracrine effects of hypoxia on monocyte-osteoclast differentiation via induction of VEGF.
Knowles HJ; Athanasou NA
J Pathol; 2008 May; 215(1):56-66. PubMed ID: 18283716
[TBL] [Abstract][Full Text] [Related]
19. Expression of the forkhead transcription factor FOXP1 is associated both with hypoxia inducible factors (HIFs) and the androgen receptor in prostate cancer but is not directly regulated by androgens or hypoxia.
Banham AH; Boddy J; Launchbury R; Han C; Turley H; Malone PR; Harris AL; Fox SB
Prostate; 2007 Jul; 67(10):1091-8. PubMed ID: 17477366
[TBL] [Abstract][Full Text] [Related]
20. Formation of Renal Cysts and Tumors in Vhl/Trp53-Deficient Mice Requires HIF1α and HIF2α.
Schönenberger D; Harlander S; Rajski M; Jacobs RA; Lundby AK; Adlesic M; Hejhal T; Wild PJ; Lundby C; Frew IJ
Cancer Res; 2016 Apr; 76(7):2025-36. PubMed ID: 26759234
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
