309 related articles for article (PubMed ID: 17419604)
1. In vitro optimization of non-small cell lung cancer activity with troxacitabine, L-1,3-dioxolane-cytidine, prodrugs.
Radi M; Adema AD; Daft JR; Cho JH; Hoebe EK; Alexander LE; Peters GJ; Chu CK
J Med Chem; 2007 May; 50(9):2249-53. PubMed ID: 17419604
[TBL] [Abstract][Full Text] [Related]
2. Troxacitabine prodrugs for pancreatic cancer.
Adema AD; Radi M; Daft J; Narayanasamy J; Hoebe EK; Alexander LE; Chu CK; Peters GJ
Nucleosides Nucleotides Nucleic Acids; 2007; 26(8-9):1073-7. PubMed ID: 18058539
[TBL] [Abstract][Full Text] [Related]
3. Anticancer activity of beta-L-dioxolane-cytidine, a novel nucleoside analogue with the unnatural L configuration.
Grove KL; Guo X; Liu SH; Gao Z; Chu CK; Cheng YC
Cancer Res; 1995 Jul; 55(14):3008-11. PubMed ID: 7606719
[TBL] [Abstract][Full Text] [Related]
4. Novel prodrugs of tegafur that display improved anticancer activity and antiangiogenic properties.
Engel D; Nudelman A; Tarasenko N; Levovich I; Makarovsky I; Sochotnikov S; Tarasenko I; Rephaeli A
J Med Chem; 2008 Jan; 51(2):314-23. PubMed ID: 18163551
[TBL] [Abstract][Full Text] [Related]
5. Potent antitumor activity of a novel nucleoside analogue, BCH-4556 (beta-L-dioxolane-cytidine), in human renal cell carcinoma xenograft tumor models.
Kadhim SA; Bowlin TL; Waud WR; Angers EG; Bibeau L; DeMuys JM; Bednarski K; Cimpoia A; Attardo G
Cancer Res; 1997 Nov; 57(21):4803-10. PubMed ID: 9354442
[TBL] [Abstract][Full Text] [Related]
6. N4-hydroxycytosine dioxolane nucleosides and their activity against hepatitis B virus.
Du J; Hollecker L; Shi J; Chun BK; Watanabe KA; Raymond FS; Nachman TY; Lostia S; Stuyver LJ; Otto MJ
Nucleosides Nucleotides Nucleic Acids; 2005; 24(8):1209-14. PubMed ID: 16270663
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and antitumor activity of CBI-bearing ester and carbamate prodrugs of CC-1065 analogue.
Wang Y; Li L; Tian Z; Jiang W; Larrick JW
Bioorg Med Chem; 2006 Dec; 14(23):7854-61. PubMed ID: 16908174
[TBL] [Abstract][Full Text] [Related]
8. Phosphoramidate and phosphate prodrugs of (-)-beta-D-(2R,4R)-dioxolane-thymine: synthesis, anti-HIV activity and stability studies.
Liang Y; Narayanasamy J; Schinazi RF; Chu CK
Bioorg Med Chem; 2006 Apr; 14(7):2178-89. PubMed ID: 16314108
[TBL] [Abstract][Full Text] [Related]
9. Troxacitabine (Shire Pharmaceuticals).
Ecker G
Curr Opin Investig Drugs; 2002 Oct; 3(10):1533-8. PubMed ID: 12431032
[TBL] [Abstract][Full Text] [Related]
10. Action of troxacitabine on cells transduced with human cytidine deaminase cDNA.
Boivin AJ; Gourdeau H; Momparler RL
Cancer Invest; 2004; 22(1):25-9. PubMed ID: 15069761
[TBL] [Abstract][Full Text] [Related]
11. Novel N-oxide of naphthalimides as prodrug leads against hypoxic solid tumor: synthesis and biological evaluation.
Yin H; Xu Y; Qian X; Li Y; Liu J
Bioorg Med Chem Lett; 2007 Apr; 17(8):2166-70. PubMed ID: 17331719
[TBL] [Abstract][Full Text] [Related]
12. Species differences in troxacitabine pharmacokinetics and pharmacodynamics: implications for clinical development.
Gourdeau H; Leblond L; Hamelin B; Dong K; Ouellet F; Boudreau C; Custeau D; Richard A; Gilbert MJ; Jolivet J
Clin Cancer Res; 2004 Nov; 10(22):7692-702. PubMed ID: 15570003
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and in vivo antitumor evaluation of 2-methoxyestradiol 3-phosphate, 17-phosphate, and 3,17-diphosphate.
Edsall AB; Agoston GE; Treston AM; Plum SM; McClanahan RH; Lu TS; Song W; Cushman M
J Med Chem; 2007 Dec; 50(26):6700-5. PubMed ID: 18052315
[TBL] [Abstract][Full Text] [Related]
14. Novel fluorinated prodrugs for activation by carboxypeptidase G2 showing good in vivo antitumor activity in gene-directed enzyme prodrug therapy.
Davies LC; Friedlos F; Hedley D; Martin J; Ogilvie LM; Scanlon IJ; Springer CJ
J Med Chem; 2005 Aug; 48(16):5321-8. PubMed ID: 16078849
[TBL] [Abstract][Full Text] [Related]
15. Population pharmacokinetics of troxacitabine, a novel dioxolane nucleoside analogue.
Lee CK; Rowinsky EK; Li J; Giles F; Moore MJ; Hidalgo M; Capparelli E; Jolivet J; Baker SD
Clin Cancer Res; 2006 Apr; 12(7 Pt 1):2158-65. PubMed ID: 16609029
[TBL] [Abstract][Full Text] [Related]
16. Sulfonyl-containing aldophosphamide analogues as novel anticancer prodrugs targeted against cyclophosphamide-resistant tumor cell lines.
Jain M; Fan J; Baturay NZ; Kwon CH
J Med Chem; 2004 Jul; 47(15):3843-52. PubMed ID: 15239662
[TBL] [Abstract][Full Text] [Related]
17. New Taxol (paclitaxel) prodrugs designed for ADEPT and PMT strategies in cancer chemotherapy.
Alaoui AE; Saha N; Schmidt F; Monneret C; Florent JC
Bioorg Med Chem; 2006 Jul; 14(14):5012-9. PubMed ID: 16554162
[TBL] [Abstract][Full Text] [Related]
18. Identification of CKD-516: a potent tubulin polymerization inhibitor with marked antitumor activity against murine and human solid tumors.
Lee J; Kim SJ; Choi H; Kim YH; Lim IT; Yang HM; Lee CS; Kang HR; Ahn SK; Moon SK; Kim DH; Lee S; Choi NS; Lee KJ
J Med Chem; 2010 Sep; 53(17):6337-54. PubMed ID: 20690624
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and biological activity of prodrug inhibitors of the thioredoxin-thioredoxin reductase system.
Wipf P; Lynch SM; Powis G; Birmingham A; Englund EE
Org Biomol Chem; 2005 Nov; 3(21):3880-2. PubMed ID: 16240002
[TBL] [Abstract][Full Text] [Related]
20. Effect of hypoxia on the expression of phosphoglycerate kinase and antitumor activity of troxacitabine and gemcitabine in non-small cell lung carcinoma.
Lam W; Bussom S; Cheng YC
Mol Cancer Ther; 2009 Feb; 8(2):415-23. PubMed ID: 19208827
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]