BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

305 related articles for article (PubMed ID: 17426345)

  • 1. Metabolic targeting as an anticancer strategy: dawn of a new era?
    Pan JG; Mak TW
    Sci STKE; 2007 Apr; 2007(381):pe14. PubMed ID: 17426345
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors.
    Zhang W; Hu X; Zhou W; Tam KY
    J Proteome Res; 2018 Sep; 17(9):3012-3021. PubMed ID: 30028142
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metabolic Modulation of Clear-cell Renal Cell Carcinoma with Dichloroacetate, an Inhibitor of Pyruvate Dehydrogenase Kinase.
    Kinnaird A; Dromparis P; Saleme B; Gurtu V; Watson K; Paulin R; Zervopoulos S; Stenson T; Sutendra G; Pink DB; Carmine-Simmen K; Moore R; Lewis JD; Michelakis ED
    Eur Urol; 2016 Apr; 69(4):734-744. PubMed ID: 26433571
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Therapeutic Targeting of the Pyruvate Dehydrogenase Complex/Pyruvate Dehydrogenase Kinase (PDC/PDK) Axis in Cancer.
    Stacpoole PW
    J Natl Cancer Inst; 2017 Nov; 109(11):. PubMed ID: 29059435
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism.
    Pathania D; Millard M; Neamati N
    Adv Drug Deliv Rev; 2009 Nov; 61(14):1250-75. PubMed ID: 19716393
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sodium dichloroacetate selectively targets cells with defects in the mitochondrial ETC.
    Stockwin LH; Yu SX; Borgel S; Hancock C; Wolfe TL; Phillips LR; Hollingshead MG; Newton DL
    Int J Cancer; 2010 Dec; 127(11):2510-9. PubMed ID: 20533281
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of mitochondrial oxidation by PDK2 inhibition reverses cisplatin resistance in head and neck cancer.
    Roh JL; Park JY; Kim EH; Jang HJ; Kwon M
    Cancer Lett; 2016 Feb; 371(1):20-9. PubMed ID: 26607904
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer.
    Michelakis ED; Webster L; Mackey JR
    Br J Cancer; 2008 Oct; 99(7):989-94. PubMed ID: 18766181
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Multi-modality imaging to assess metabolic response to dichloroacetate treatment in tumor models.
    Neveu MA; De Preter G; Joudiou N; Bol A; Brender JR; Saito K; Kishimoto S; Grégoire V; Jordan BF; Krishna MC; Feron O; Gallez B
    Oncotarget; 2016 Dec; 7(49):81741-81749. PubMed ID: 28082726
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeted reversal and phosphorescence lifetime imaging of cancer cell metabolism via a theranostic rhenium(I)-DCA conjugate.
    Yang J; Cao Q; Zhang H; Hao L; Zhou D; Gan Z; Li Z; Tong YX; Ji LN; Mao ZW
    Biomaterials; 2018 Sep; 176():94-105. PubMed ID: 29870900
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis.
    Li X; Jiang Y; Meisenhelder J; Yang W; Hawke DH; Zheng Y; Xia Y; Aldape K; He J; Hunter T; Wang L; Lu Z
    Mol Cell; 2016 Mar; 61(5):705-719. PubMed ID: 26942675
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Vitamin C activates pyruvate dehydrogenase (PDH) targeting the mitochondrial tricarboxylic acid (TCA) cycle in hypoxic
    Cenigaonandia-Campillo A; Serna-Blasco R; Gómez-Ocabo L; Solanes-Casado S; Baños-Herraiz N; Puerto-Nevado LD; Cañas JA; Aceñero MJ; García-Foncillas J; Aguilera Ó
    Theranostics; 2021; 11(8):3595-3606. PubMed ID: 33664850
    [No Abstract]   [Full Text] [Related]  

  • 13. Dichloroacetate, a selective mitochondria-targeting drug for oral squamous cell carcinoma: a metabolic perspective of treatment.
    Ruggieri V; Agriesti F; Scrima R; Laurenzana I; Perrone D; Tataranni T; Mazzoccoli C; Lo Muzio L; Capitanio N; Piccoli C
    Oncotarget; 2015 Jan; 6(2):1217-30. PubMed ID: 25544754
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Influence of dichloroacetate (DCA) on lactate production and oxygen consumption in neuroblastoma cells: is DCA a suitable drug for neuroblastoma therapy?
    Niewisch MR; Kuçi Z; Wolburg H; Sautter M; Krampen L; Deubzer B; Handgretinger R; Bruchelt G
    Cell Physiol Biochem; 2012; 29(3-4):373-80. PubMed ID: 22508045
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antitumor and chemosensitizing action of dichloroacetate implicates modulation of tumor microenvironment: a role of reorganized glucose metabolism, cell survival regulation and macrophage differentiation.
    Kumar A; Kant S; Singh SM
    Toxicol Appl Pharmacol; 2013 Nov; 273(1):196-208. PubMed ID: 24051182
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting of two aspects of metabolism in breast cancer treatment.
    Gang BP; Dilda PJ; Hogg PJ; Blackburn AC
    Cancer Biol Ther; 2014; 15(11):1533-41. PubMed ID: 25482950
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dichloroacetate Affects Mitochondrial Function and Stemness-Associated Properties in Pancreatic Cancer Cell Lines.
    Tataranni T; Agriesti F; Pacelli C; Ruggieri V; Laurenzana I; Mazzoccoli C; Sala GD; Panebianco C; Pazienza V; Capitanio N; Piccoli C
    Cells; 2019 May; 8(5):. PubMed ID: 31109089
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dichloroacetate, an inhibitor of pyruvate dehydrogenase kinases, inhibits platelet aggregation and arterial thrombosis.
    Nayak MK; Dhanesha N; Doddapattar P; Rodriguez O; Sonkar VK; Dayal S; Chauhan AK
    Blood Adv; 2018 Aug; 2(15):2029-2038. PubMed ID: 30108111
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect.
    Chen Y; Cairns R; Papandreou I; Koong A; Denko NC
    PLoS One; 2009 Sep; 4(9):e7033. PubMed ID: 19753307
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Acidosis-induced metabolic reprogramming in tumor cells enhances the anti-proliferative activity of the PDK inhibitor dichloroacetate.
    Schoonjans CA; Joudiou N; Brusa D; Corbet C; Feron O; Gallez B
    Cancer Lett; 2020 Feb; 470():18-28. PubMed ID: 31812695
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.