These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 17427948)

  • 1. Targeted molecular dynamics simulation studies of binding and conformational changes in E. coli MurD.
    Perdih A; Kotnik M; Hodoscek M; Solmajer T
    Proteins; 2007 Jul; 68(1):243-54. PubMed ID: 17427948
    [TBL] [Abstract][Full Text] [Related]  

  • 2. "Open" structures of MurD: domain movements and structural similarities with folylpolyglutamate synthetase.
    Bertrand JA; Fanchon E; Martin L; Chantalat L; Auger G; Blanot D; van Heijenoort J; Dideberg O
    J Mol Biol; 2000 Sep; 301(5):1257-66. PubMed ID: 10966819
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibitor design strategy based on an enzyme structural flexibility: a case of bacterial MurD ligase.
    Perdih A; Hrast M; Barreteau H; Gobec S; Wolber G; Solmajer T
    J Chem Inf Model; 2014 May; 54(5):1451-66. PubMed ID: 24724969
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structure of Escherichia coli UDPMurNAc-tripeptide d-alanyl-d-alanine-adding enzyme (MurF) at 2.3 A resolution.
    Yan Y; Munshi S; Leiting B; Anderson MS; Chrzas J; Chen Z
    J Mol Biol; 2000 Dec; 304(3):435-45. PubMed ID: 11090285
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MurD ligase from E. coli: Tetrahedral intermediate formation study by hybrid quantum mechanical/molecular mechanical replica path method.
    Perdih A; Hodoscek M; Solmajer T
    Proteins; 2009 Feb; 74(3):744-59. PubMed ID: 18704940
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Invariant amino acids in the Mur peptide synthetases of bacterial peptidoglycan synthesis and their modification by site-directed mutagenesis in the UDP-MurNAc:L-alanine ligase from Escherichia coli.
    Bouhss A; Mengin-Lecreulx D; Blanot D; van Heijenoort J; Parquet C
    Biochemistry; 1997 Sep; 36(39):11556-63. PubMed ID: 9305945
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure of Escherichia coli UDP-N-acetylmuramoyl:L-alanine ligase (MurC).
    Deva T; Baker EN; Squire CJ; Smith CA
    Acta Crystallogr D Biol Crystallogr; 2006 Dec; 62(Pt 12):1466-74. PubMed ID: 17139082
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modeling of Enterococcus faecalis D-alanine:D-alanine ligase: structure-based study of the active site in the wild-type enzyme and in glycopeptide-dependent mutants.
    Prévost M; Van Belle D; Tulkens PM; Courvalin P; Van Bambeke F
    J Mol Microbiol Biotechnol; 2000 Jul; 2(3):321-30. PubMed ID: 10937441
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel naphthalene-N-sulfonyl-D-glutamic acid derivatives as inhibitors of MurD, a key peptidoglycan biosynthesis enzyme.
    Humljan J; Kotnik M; Contreras-Martel C; Blanot D; Urleb U; Dessen A; Solmajer T; Gobec S
    J Med Chem; 2008 Dec; 51(23):7486-94. PubMed ID: 19007109
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and structure-activity relationships of new phosphinate inhibitors of MurD.
    Strancar K; Blanot D; Gobec S
    Bioorg Med Chem Lett; 2006 Jan; 16(2):343-8. PubMed ID: 16271472
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Peptide inhibitors of MurD and MurE, essential enzymes of bacterial cell wall biosynthesis.
    Bratkovic T; Lunder M; Urleb U; Strukelj B
    J Basic Microbiol; 2008 Jun; 48(3):202-6. PubMed ID: 18506905
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NMR and molecular dynamics study of the binding mode of naphthalene-N-sulfonyl-D-glutamic acid derivatives: novel MurD ligase inhibitors.
    Simcic M; Hodoscek M; Humljan J; Kristan K; Urleb U; Kocjan D; Grdadolnik SG
    J Med Chem; 2009 May; 52(9):2899-908. PubMed ID: 19358612
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MurD enzymes from different bacteria: evaluation of inhibitors.
    Barreteau H; Sosič I; Turk S; Humljan J; Tomašić T; Zidar N; Hervé M; Boniface A; Peterlin-Mašič L; Kikelj D; Mengin-Lecreulx D; Gobec S; Blanot D
    Biochem Pharmacol; 2012 Sep; 84(5):625-32. PubMed ID: 22705647
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design.
    Krajewski WW; Collins R; Holmberg-Schiavone L; Jones TA; Karlberg T; Mowbray SL
    J Mol Biol; 2008 Jan; 375(1):217-28. PubMed ID: 18005987
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Catalytic mechanism of l,l-diaminopimelic acid with diaminopimelate epimerase by molecular docking simulations.
    Brunetti L; Galeazzi R; Orena M; Bottoni A
    J Mol Graph Model; 2008 Apr; 26(7):1082-90. PubMed ID: 18023379
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A novel 2-oxoindolinylidene inhibitor of bacterial MurD ligase: Enzyme kinetics, protein-inhibitor binding by NMR and a molecular dynamics study.
    Simčič M; Pureber K; Kristan K; Urleb U; Kocjan D; Grdadolnik SG
    Eur J Med Chem; 2014 Aug; 83():92-101. PubMed ID: 24952377
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crystallographic Study of Peptidoglycan Biosynthesis Enzyme MurD: Domain Movement Revisited.
    Šink R; Kotnik M; Zega A; Barreteau H; Gobec S; Blanot D; Dessen A; Contreras-Martel C
    PLoS One; 2016; 11(3):e0152075. PubMed ID: 27031227
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of new inhibitors of the bacterial peptidoglycan biosynthesis enzymes MurD and MurF by structure-based virtual screening.
    Turk S; Kovac A; Boniface A; Bostock JM; Chopra I; Blanot D; Gobec S
    Bioorg Med Chem; 2009 Mar; 17(5):1884-9. PubMed ID: 19223185
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Exploring the conformational changes of the ATP binding site of gyrase B from Escherichia coli complexed with different established inhibitors by using molecular dynamics simulation: protein-ligand interactions in the light of the alanine scanning and free energy decomposition methods.
    Saíz-Urra L; Cabrera MA; Froeyen M
    J Mol Graph Model; 2011 Feb; 29(5):726-39. PubMed ID: 21216167
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-based design of a new series of D-glutamic acid based inhibitors of bacterial UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (MurD).
    Tomasić T; Zidar N; Sink R; Kovac A; Blanot D; Contreras-Martel C; Dessen A; Müller-Premru M; Zega A; Gobec S; Kikelj D; Masic LP
    J Med Chem; 2011 Jul; 54(13):4600-10. PubMed ID: 21591605
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.