119 related articles for article (PubMed ID: 17431793)
1. Conformational change in the active center region of GST P1-1, due to binding of a synthetic conjugate of DXR with GSH, enhanced JNK-mediated apoptosis.
Asakura T; Sasagawa A; Takeuchi H; Shibata S; Marushima H; Mamori S; Ohkawa K
Apoptosis; 2007 Jul; 12(7):1269-80. PubMed ID: 17431793
[TBL] [Abstract][Full Text] [Related]
2. The association of deamidation of Bcl-xL and translocation of Bax to the mitochondria through activation of JNK in the induction of apoptosis by treatment with GSH-conjugated DXR.
Asakura T; Maeda K; Omi H; Matsudaira H; Ohkawa K
Int J Oncol; 2008 Aug; 33(2):389-95. PubMed ID: 18636161
[TBL] [Abstract][Full Text] [Related]
3. Caspase-3 activation during apoptosis caused by glutathione-doxorubicin conjugate.
Asakura T; Sawai T; Hashidume Y; Ohkawa Y; Yokoyama S; Ohkawa K
Br J Cancer; 1999 May; 80(5-6):711-5. PubMed ID: 10360648
[TBL] [Abstract][Full Text] [Related]
4. Peptide-bond modified glutathione conjugate analogs modulate GSTpi function in GSH-conjugation, drug sensitivity and JNK signaling.
Burg D; Riepsaame J; Pont C; Mulder G; van de Water B
Biochem Pharmacol; 2006 Jan; 71(3):268-77. PubMed ID: 16337611
[TBL] [Abstract][Full Text] [Related]
5. Suppression of GST-P by treatment with glutathione-doxorubicin conjugate induces potent apoptosis in rat hepatoma cells.
Asakura T; Hashizume Y; Tashiro K; Searashi Y; Ohkawa K; Nishihira J; Sakai M; Shibasaki T
Int J Cancer; 2001 Oct; 94(2):171-7. PubMed ID: 11668494
[TBL] [Abstract][Full Text] [Related]
6. Critical role of oxidative stress and sustained JNK activation in aloe-emodin-mediated apoptotic cell death in human hepatoma cells.
Lu GD; Shen HM; Chung MC; Ong CN
Carcinogenesis; 2007 Sep; 28(9):1937-45. PubMed ID: 17698970
[TBL] [Abstract][Full Text] [Related]
7. The anti-cancer drug chlorambucil as a substrate for the human polymorphic enzyme glutathione transferase P1-1: kinetic properties and crystallographic characterisation of allelic variants.
Parker LJ; Ciccone S; Italiano LC; Primavera A; Oakley AJ; Morton CJ; Hancock NC; Bello ML; Parker MW
J Mol Biol; 2008 Jun; 380(1):131-44. PubMed ID: 18511072
[TBL] [Abstract][Full Text] [Related]
8. Prx1 suppresses radiation-induced c-Jun NH2-terminal kinase signaling in lung cancer cells through interaction with the glutathione S-transferase Pi/c-Jun NH2-terminal kinase complex.
Kim YJ; Lee WS; Ip C; Chae HZ; Park EM; Park YM
Cancer Res; 2006 Jul; 66(14):7136-42. PubMed ID: 16849559
[TBL] [Abstract][Full Text] [Related]
9. Glutathione S-transferase pi regulates UV-induced JNK signaling in SH-SY5Y neuroblastoma cells.
Castro-Caldas M; Milagre I; Rodrigues E; Gama MJ
Neurosci Lett; 2009 Feb; 451(3):241-5. PubMed ID: 19159663
[TBL] [Abstract][Full Text] [Related]
10. Glutamine attenuates tubular cell apoptosis in acute kidney injury via inhibition of the c-Jun N-terminal kinase phosphorylation of 14-3-3.
Kim YS; Jung MH; Choi MY; Kim YH; Sheverdin V; Kim JH; Ha HJ; Park DJ; Kang SS; Cho GJ; Choi WS; Chang SH
Crit Care Med; 2009 Jun; 37(6):2033-44. PubMed ID: 19384198
[TBL] [Abstract][Full Text] [Related]
11. 4-Aryl-1,3,2-oxathiazolylium-5-olate: a novel GST inhibitor to release JNK and activate c-Jun for cancer therapy.
Cui H; Shen J; Lu D; Zhang T; Zhang W; Sun D; Wang PG
Cancer Chemother Pharmacol; 2008 Aug; 62(3):509-15. PubMed ID: 18008069
[TBL] [Abstract][Full Text] [Related]
12. Glutathione-S-transferase-pi expression regulates sensitivity to glutathione-doxorubicin conjugate.
Tashiro K; Asakura T; Fujiwara C; Ohkawa K; Ishibashi Y
Anticancer Drugs; 2001 Sep; 12(8):707-12. PubMed ID: 11604559
[TBL] [Abstract][Full Text] [Related]
13. Brostallicin, a novel anticancer agent whose activity is enhanced upon binding to glutathione.
Geroni C; Marchini S; Cozzi P; Galliera E; Ragg E; Colombo T; Battaglia R; Howard M; D'Incalci M; Broggini M
Cancer Res; 2002 Apr; 62(8):2332-6. PubMed ID: 11956092
[TBL] [Abstract][Full Text] [Related]
14. Relationship between cytocidal activity and glutathione-S-transferase inhibition using doxorubicin coupled to stereoisomers of glutathione with different substrate specificity.
Hashizume Y; Asakura T; Oikawa T; Yamauchi T; Soda K; Ohkawa K
Anticancer Drugs; 2001 Jul; 12(6):549-54. PubMed ID: 11460002
[TBL] [Abstract][Full Text] [Related]
15. Proapoptotic activity of new glutathione S-transferase inhibitors.
Turella P; Cerella C; Filomeni G; Bullo A; De Maria F; Ghibelli L; Ciriolo MR; Cianfriglia M; Mattei M; Federici G; Ricci G; Caccuri AM
Cancer Res; 2005 May; 65(9):3751-61. PubMed ID: 15867371
[TBL] [Abstract][Full Text] [Related]
16. Downregulation of GSTpi expression by tryptanthrin contributing to sensitization of doxorubicin-resistant MCF-7 cells through c-jun NH2-terminal kinase-mediated apoptosis.
Yu ST; Chen TM; Chern JW; Tseng SY; Chen YH
Anticancer Drugs; 2009 Jun; 20(5):382-8. PubMed ID: 19318911
[TBL] [Abstract][Full Text] [Related]
17. Class Pi glutathione transferase unfolds via a dimeric and not monomeric intermediate: functional implications for an unstable monomer.
Gildenhuys S; Wallace LA; Burke JP; Balchin D; Sayed Y; Dirr HW
Biochemistry; 2010 Jun; 49(24):5074-81. PubMed ID: 20481548
[TBL] [Abstract][Full Text] [Related]
18. Chronic high-dose morphine treatment promotes SH-SY5Y cell apoptosis via c-Jun N-terminal kinase-mediated activation of mitochondria-dependent pathway.
Lin X; Wang YJ; Li Q; Hou YY; Hong MH; Cao YL; Chi ZQ; Liu JG
FEBS J; 2009 Apr; 276(7):2022-36. PubMed ID: 19292871
[TBL] [Abstract][Full Text] [Related]
19. Diuretic drug binding to human glutathione transferase P1-1: potential role of Cys-101 revealed in the double mutant C47S/Y108V.
Quesada-Soriano I; Parker LJ; Primavera A; Wielens J; Holien JK; Casas-Solvas JM; Vargas-Berenguel A; Aguilera AM; Nuccetelli M; Mazzetti AP; Lo Bello M; Parker MW; García-Fuentes L
J Mol Recognit; 2011; 24(2):220-34. PubMed ID: 20540076
[TBL] [Abstract][Full Text] [Related]
20. Ionizing radiation utilizes c-Jun N-terminal kinase for amplification of mitochondrial apoptotic cell death in human cervical cancer cells.
Kim MJ; Lee KH; Lee SJ
FEBS J; 2008 May; 275(9):2096-108. PubMed ID: 18373696
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
